Chapter 831 Opening up a new era (second update, please subscribe)
Many times, only the 1% of people have a flash of inspiration that can change the world.
Human progress depends on these inspirations.
As the saying goes, the best way to solve a problem is to face it. The more problems you face, the more problems you can solve, and the more inspiration you will naturally get.
After an occasional inspiration, what do you need?
Of course it's sweat.
Under the light of the shadowless lamp, a special operation is being carried out nervously and orderly. The person on the operating table is not a human, but a deeply anesthetized orangutan. Zhang Wenguang is wearing a surgical suit, mask and gloves. Although there is sweat on his forehead, the movements in his hands are extremely skillful.
Soon, he took out a kidney from the orangutan's body. Under the light, it looked extremely fresh, as if it still had the warmth of life.
"Record, start organ transplantation."
When Zhang Wenguang spoke, the assistants cooperated tacitly, and every step of the operation was done carefully, for fear of causing any harm to the experimental subjects.
As the operation progressed, the atmosphere became increasingly tense. Beads of sweat began to form on their foreheads.
"Wipe the sweat."
The nurse quickly wiped his sweat. When the nurse wiped the sweat, Zhang Wenguang did not stop his movements, but focused more on the operation.
Finally, the operation was over, and the kidney of one orangutan was successfully implanted into another orangutan. Zhang Wenguang breathed a sigh of relief, but his face did not show much joy, because the success of the operation was only the first step, and the real challenge was yet to come.
"Doctor, was it successful?"
Facing the question from his colleague, Zhang Wenguang shook his head and said.
“Only when rejection is overcome can real success be achieved!”
Although medical scientists performed a series of kidney transplants on animals in 1912, due to rejection, , the test body can only last for a few days or months.
A few years ago, Zhang Wenguang, who was still a graduate student, turned his research direction to organ transplantation. Since then, he has conducted dozens of animal experiments. In order to overcome rejection, he A large number of drugs have also been tested in an attempt to use drugs to suppress rejection, but the results have always been unsatisfactory.
Although the effect is not ideal, through a large number of experiments, the principle of rejection reaction has been basically clarified, which is also a big progress.
"I know, doctor, I mean, does the drug tested this time have a chance?"
After thinking for a moment, Zhang Wenguang said.
“Last year, the US FDA approved mercaptopurine for the treatment of childhood leukemia. The effect of this drug is very good. The life expectancy of treated children with leukemia is about 3 months, but after taking mercaptopurine treatment , the median survival time increased to 12 months. The lymphocytes of leukemia are similar to the formation of lymphocytes during the inflammatory reaction, so I think that by taking it, the rejection reaction should be suppressed.”
A few months ago, after seeing the paper on the use of mercaptopurine in the treatment of childhood leukemia, Zhang Wenguang studied its working principle and finally came to the conclusion that this new drug, which was just approved for use last year, is very It has the potential to bring about earth-shaking changes in organ transplantation.
Of course, this is just an academic speculation, and it must be proven by experiments in the end.
Zhang Wenguang looked at the orangutan being pushed out by the nurse and said.
"Leave the rest to time."
After saying that, he looked at the time.
June 24, 3:11 in the morning.
Experimental record: The operation is completed and postoperative observation begins...
On the same day, although the operation was over, Zhang Wenguang did not leave the hospital. Instead, he kept observing the animals that had not yet awakened. In the following days, he would enter the laboratory to visit the two test subjects every day.
The test subject is slowly recovering.
One day, two days, three days...
Usually, kidney homografts stop functioning after 4-8 days, but after taking thiopurine daily, not only those who received a kidney transplant The orangutans are still alive, and even the orangutans with only one kidney are still alive and well.
After a full hundred days, the two orangutans, which had fully recovered, even began to behave like normal orangutans outdoors.
Facing the two orangutans that had fully recovered, Zhang Wenguang had a look of joy on his face all day long. "It's time to prepare the paper."
This paper will definitely shock the whole world and bring unprecedented shock to the medical community around the world.
......
As usual, Sun Zhiyu came to the hospital again. As soon as he got out of the elevator, a nurse said to him over there.
"Mr. Sun, you are finally here. Your brother went crazy again and smashed things everywhere. We finally tied him to the bed."
"I'm sorry for causing you trouble again."< br>
Sun Zhiyu apologized quickly.
"Go and see him, maybe he will be nicer to you."
Nodding, Sun Zhiyu's expression looked a little heavy. Last year, when his brother Sun Zhihe was working in the company , suddenly fell down without warning. When he arrived at the hospital, he discovered that his kidneys had suddenly failed. The doctor told him that there was no treatment for kidney failure and that he only had about 2 years left.
Sun Zhiyu couldn't accept the sudden bad news. After all, he had told his mother that he would take Zhihe home with him in the future.
But Zhihe's condition deteriorated faster than expected. By June of the following year, he could hardly walk. The condition is already very serious. The uremia affected his brain and made him very aggressive. He kept cursing the medical staff, wanted to pull out all the catheters on his body, and even trembled violently and had convulsions.
Are you really going to lose your brother?
Finally arrived at the ward. The messy ward had not had time to clean up. As soon as he entered the ward, before Sun Zhiyu could speak, Sun Zhihe, who was tied to the bed, had a ferocious look on his face and stared at him with red eyes. shouted.
“Get out, get out!”
Seeing his brother's irritable look, Sun Zhiyu couldn't believe that this was the third child who always smiled when he spoke.
"Zhihe, it's me, I'm your eldest brother, I'm the eldest brother!"
"Get out, get out quickly..."
Sun Zhihe didn't seem to recognize Sun Zhiyu felt extremely heartbroken when he came out and looked at his brother's appearance. After leaving the ward, he went to see the attending physician and told the doctor that he was willing to do everything possible to help his brother:
"Doctor, I would give him one of my kidneys if it would help, I know, we have two kidneys.”
The doctor told Sun Zhiyu.
"Mr. Sun, although you have a good idea, organ transplantation is not feasible because accepting other people's organs will cause the body's rejection. To put it simply, your own immune system cannot recognize the transplant. The organ was treated as a foreign body and destroyed."
But the doctor suddenly stopped because he remembered something he had heard from another classmate.
So he asked.
"Are you sure? Mr. Sun."
"I'm sure, Dr. Lin, when I left Tangshan, I told my mother that I would definitely take Zhihe home in the future. Please beg Doctor Qi. As long as I can save him, I will do anything."
For Sun Zhiyu In other words, as long as the brother is still alive, he still has his own relatives in this land. But if the brother dies. He was the only one left in this land.
In the future, when he returns to Tangshan one day, how will he explain all this to his mother?
"Doctor, give him mine. We are brothers. Give him mine. Please, you must save him! He is the only relative in Nanyang. If there is no more... I am left alone. When the time comes, how can I explain it to my mother?”
The doctor was moved by Sun Zhiyu’s pleading.
"Well, let me think about it..."
The doctor thought for a while and said.
"I can help you contact a doctor! He may have a solution."
(End of this chapter)