Chapter 387 First Pass Effect


Chapter 387 First Pass Effect

“Then the patient also has to pay for this bottle of glucose?”

“That’s for sure, I’ve done it in the hospital, let alone a A bottle of candy, even a piece of thread, is worth it. There must be a source of reimbursement."

"That's not good, look at that era, it was nothing. It’s better to take a needle and a thread from the masses.”

“What’s the matter with a drink? How much is a bottle of glucose worth? I’ll give it to Director Wu.”< br>


"The environment in China has been ruined by you people. Do you want patients to reimburse you? You are just criticizing here. Why, you all know it? To say the least, even if you really want patients to reimburse you, , we are also willing, what are you doing?"

...

For a time, the incident about a bottle of glucose directly triggered a barrage storm.

Wu Xiaofu also didn’t expect that drinking a bottle of glucose would lead to so many things. He is tall and heavy. As a young man, he eats a lot and gets hungry quickly, especially when he works hard. , Sometimes, when I am working in the operating room and feel uncomfortable with an empty stomach, I drink a bottle of candy.

This glucose really doesn’t taste good, but Wu Xiaofu is not picky. It’s better than the feeling of an empty stomach.

This gradually became a habit.

Between operations, you might just open a bottle and do it. Generally speaking, no one else knows about what happens in the operating room. People in the operating room don’t do nothing but take pictures of things. Post, especially Wu Xiaofu’s video.

This time, the program team sent it, otherwise, this segment would not be broadcast at all.

However, it is still unclear whether this was approved by the hospital, because the main shot of this paragraph is not here, but on Cheng Shi's sutures. When it came to Wu Xiaofu, no one looked at Cheng Shi anymore, and Wu Xiaofu became the protagonist.

Is it an unintentional mistake by the program team, something went wrong during the review of the film in the hospital, or is there something wrong with some joint in the middle?

Ordinarily, a film containing such controversial footage should not be released.

Unless someone wants to mess with Wu Xiaofu, because after such a film is released, no matter how you explain it, people who are stubborn will not listen. They cannot see or listen to some professional remarks. The next time they saw Wu Xiaofu, they had only one impression, that is, Wu Xiaofu ate and took the patient's things for free.

Impression is something that is really difficult to erase.

So, at this time, Wu Xiaofu couldn't help but frowned when he saw all this. The most important thing was that no one contacted him after the program was broadcast last night for such a big thing.

The show is still going on, Wu Xiaofu is not in a hurry to do anything, just watching quietly.

Because the program is broadcast on Donghai Satellite TV, or broadcast live, and there are no barrages when watching it on TV. Only people like Wu Xiaofu, who watch it with video software, can have barrages. When it was broadcast, Jiang Ruonan They couldn't see these barrages, so in this clip, everything passed so smoothly.

It seems that no one noticed the scene of Wu Xiaofu drinking glucose.

Everything seems to be just a coincidence. Only the audience divided into two groups on the barrage, arguing against each other, represents that this detail has been infinitely magnified.

“I don’t know if you have noticed a small detail, that is, when classmate Cheng Shi was doing sutures, Teacher Wu also entered the country later.”

“Well, yes We really didn’t pay much attention to it, but it was normal for the surgeon, Teacher Wu, to enter the country. Could there be something interesting happening?”

A total of two floating guests were invited to this program. One of them was named "Fengtong", a traffic niche who had just debuted. When the clips of the interns were almost played, Fengtong suddenly spoke, and the other guests seemed to also As if waking up from a dream, Jiang Ruonan immediately asked, which could be said to have completely brought the topic here.

For this reason, the program replayed the clip. Now, I can see everything clearly.

"This, Teacher Wu, seems to be drinking glucose?"

Jiang Ruonan said slowly, and the other guests nodded quickly, "You are indeed drinking glucose. "It should be that Teacher Wu was too tired during the operation and may have had low blood sugar. He did this in order to replenish sugar in time. After all, the food didn't taste good. If it wasn't an emergency, no one would drink it."

Bai Xiaoyan answered Jiang Ruonan's words, and everyone was surprised when they heard the words.

"Teacher Bai seems to have experience. Has he also drank glucose?"

Hearing this, Bai Xiaoyan did not hide anything and said frankly, "To be honest with you, I I actually drank it. It was when I was a teenager. I was getting an infusion when I was sick. I disliked how slow the infusion was. I said it was going to be infusing one at a time. How long would it take for the infusion to take place? So I just took the bottle. I picked it up, cut it open with scissors, and drank it.

When my mother found out, I had already taken a big sip, and she quickly grabbed it.

But even she didn't. Damn, I won't drink it anymore. It's really unpleasant to drink. Someone told me before that it was sugar water. I thought it was the same as a drink. It should be sweet and delicious, but I didn't realize it until I drank it. , it’s completely different, the sweetness is almost unnoticeable, and it also has a astringent taste, which feels weird.

It was really weird, so I still remember it vividly. "

What a tiger!

When everyone heard this, they couldn't help but think, after all, although they all said that losing is too slow, it is better to drink directly, but no one actually drank it directly. .

However, for a child, this behavior is considered normal.

Everyone laughed, and the show was very happy.

"By the way, talking about this matter, I really have a question to ask. Is there really any difference between the effect of this infusion and the effect of drinking it directly?"

Everyone also looked at Lin Wei after hearing this. , after all, there is only such a professional among the guests in the program group.

The audience is also a little curious. In their concept, it seems that the effect of infusion is better than drinking it directly. Otherwise, they would drink it directly, and there is no point in losing it slowly. But the reason What it is, it doesn’t seem to be that clear.

Lin Wei also smiled when everyone looked at her.

“When talking about this issue, we have to mention a word called ‘first pass elimination’, also known as the first pass effect. I don’t know if you have heard of it. It means that certain drugs are eliminated for the first time. When passing through the intestinal mucosa and liver, it is partially metabolized and inactivated, reducing the amount of drug entering the systemic circulation.

For example, the first-pass effect of nitroglycerin is over 90%, so oral administration has poor efficacy.

It’s like collecting tolls. You can obviously earn more, but after being tolled one after another, you won’t end up with that much.

The same principle applies to medication. If you drink the liquid directly, the absorption site is in the stomach and small intestine. From the entrance to here, there are too many intermediate links. If you want to be 100% Absorption and utilization are simply impossible, and are also affected by factors such as fasting, gastrointestinal motility, gastrointestinal pH, drug dissolution and release rate, etc.

Intravenous administration is different. It directly eliminates the intermediate link and is 100% absorbed. This is the main reason why hospitals choose infusion for treatment. ”

(End of this chapter)

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