Pan Ye distributed the paper information of these two medicines to the first person present.
The overseas doctors from the two hospitals took the information with confusion and browsed it quickly, wanting to see what tricks the traditional Chinese medicine hospital could do.
Lin Sanqi continued to cheat:
"To be honest, I have a medical team with very strong scientific research capabilities behind me. Don't ask where it is.
According to research by our team, if the isoniazid + streptomycin model is used alone, the tuberculosis treatment rate is only 33%, less than half, and the side effects are very serious.
For example, operations on the liver and kidneys can cause strong ototoxicity, which can easily lead to deafness in patients, especially children.
In order to continue selling the drug, the manufacturer of streptomycin has been covering up this serious side effect. If you just go to the pediatrician and ask around, you can find out this amazing inside story.
Not only the side effects, but also the course of this dual therapy takes about 24 months.
If you encounter refractory pulmonary tuberculosis, the course of the disease will be prolonged, which not only increases the financial burden on the patient, but also makes it difficult for some patients to bear the risks of related complications. After all, the longer the medication is taken, the more toxic the drug will be. ”
The doctors studying abroad nodded one after another, obviously having no objections to these points put forward by Lin Sanqi.
As Lin Sanqi explained, he moved slowly among the crowd, ensuring that everyone could hear his words.
“So our team carried out a comprehensive reform based on isoniazid + streptomycin and discovered the use of quadruple therapy of isoniazid, rifampicin, pyrazinamide, and ethambutol.
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We found that when these four drugs are used together, the effect is better and the course of treatment is shorter. Of course, this is not just an empty talk. We have relevant data and have written it down in the information. ”
(The data is absolutely real, Lin Sanqi copied all ready-made information)
However, as people who have studied abroad and have rigorous modern medical attitudes, the 20 doctors present at the Union Medical College and Digital Hospital were all dubious. They did not just believe what Lin Sanqi said.
Lin Sanqi didn't take it seriously. Anyway, every word he said and every information he gave has been tested for decades. It is absolutely authoritative, credible, and can withstand time and clinical testing. , so I am full of confidence:
"About the two new drugs rifampicin and ethambutol, let me briefly explain here:
Lifuco is a broad-spectrum antibiotic drug that has a strong antibacterial effect against Mycobacterium tuberculosis and is also effective against Gram-positive or negative bacteria and viruses. It is mainly used to treat tuberculosis, meningitis and Staphylococcus aureus infections.
Ethambutol is a bacteriostatic and anti-tuberculosis drug. Its mechanism of action is that it can penetrate into mycobacteria and interfere with RNA synthesis to inhibit bacterial reproduction. It has a very clear inhibitory effect on mycobacteria in the growth and reproduction period.
Let me use another analogy. The four drugs, isoniazid, rifampicin, pyrazinamide, and ethambutol, have their own responsibilities and functions when treating tuberculosis. I will use the word "war" to describe it:
For example, "isoniazid" is a pioneer in the fight against tuberculosis.
As a powerful anti-tuberculosis drug is currently on the market, we first use isoniazid to attack the tuberculosis bacilli, bombing them violently, and suppressing the enemy's arrogance first.
As for "rifampicin", it can be regarded as the main force in the treatment of tuberculosis.
Because rifampicin has a more comprehensive bactericidal effect and even has a certain killing effect on some bacteria that are already broad-spectrum drug-resistant, this drug relies on killing the large army of Mycobacterium tuberculosis.
"Ethambutol" is the blocking force in the anti-tuberculosis program.
Mainly because it does not produce poor resistance to other anti-tuberculosis drugs, that is, the regimen with its presence can enhance the efficacy of the entire treatment regimen while delaying the development of bacterial resistance.
If during treatment, you encounter stubborn Mycobacterium tuberculosis that wants to escape, ethambutol can be used to remove it at a targeted location to prevent the breakthrough.
Finally, "pyrazinamide" is a scavenger among anti-tuberculosis drugs. Its biggest feature is that it can kill intracellular tuberculosis bacteria.
Because tuberculosis bacteria are so tenacious, even if they are phagocytosed by macrophages, the single king soldiers of the immune system, they may survive and proliferate tenaciously, and even burst and kill macrophages.
This is a quite terrifying ability, which means that tuberculosis bacteria can travel in the blood and spread throughout the body with the help of macrophages. It can spread to the brain and cause meningitis, which may be fatal.
Pyrazinamide is a kind of tuberculosis bacteria that can kill the tuberculosis bacteria in the corners of the body, preventing deserters or any lurking troublemakers. It is a real scavenger.
Our research shows that if these four drugs are used in combination, the average patient can be completely cured in just 6 months, with a cure rate of almost 95%.
Of course you will say, didn’t you say it can be cured 100%?
You are all Western medicine doctors. You know that if you use too much antibiotics, resistance will develop over time. Of the four drugs I just mentioned, three are bactericidal drugs and one is antibacterial. Over time, resistance will easily develop.
At this time, it is time to use second-line drugs. We will talk about this second-line drug later. As long as we master this quadruple therapy, we can cure the vast majority of tuberculosis. This is where I feel confident. ”
After listening to this, the doctors studying abroad were all silent for a long time.
Everyone was evaluating the logic and medical and pharmacological loopholes of these four medicines, but after thinking for a long time, they all felt that what Lin Sanqi said seemed very reliable.
At this time Yang Guang couldn't help raising his hand and asked:
"Director Lin, we have understood your explanation, so now there is only one question left. How many cases of clinical cure data did you write in it, but you were unable to provide the source of the data, so even if you publish the paper, it will not be recognized. .
So we need your domestic data, such as how many patients you have treated, what is the cure rate, etc. Of course, it’s not just what you say. This requires the patient’s medical records, including chest X-rays, sputum culture reports, etc. ”
As soon as Yang Guang said this, the other doctors nodded.
Lin Sanqi thought to herself, these 20 doctors are not as easy to fool as freshly graduated college students and apprentices. No wonder these people are miserable in the end, because they will question everything others say and do not believe in authority. And be brave enough to raise objections.
Perhaps in this era, people who are too sober are not popular.
But Lin Sanqi has received modern education and knows what tolerance is, so he didn't feel offended at all by Yang Guang's outspokenness.
Lin Sanqi knew that on the first day of contact with them, there was no way he could convince them, and there was no way he could establish his authority in one day.
What's more, he doesn't need this kind of authority worship. Everyone is a doctor and an independent individual. There is no need to engage in personality worship, as long as everyone does his or her best.
"Dr. Yang asked this question well. Let me tell you about the current situation first. The current situation is in China. So far, I have treated 11 people with quadruple therapy. One of them is my future father-in-law and the father of Comrade Pan Ye next to me. .
The result of this first case can be judged as recovery. Both the X-ray and subsequent sputum examination confirmed that there is no tuberculosis. I have all the specific cases and checklists here, and you can check them at any time.
Of course, I know that one case does not mean anything. Tuberculosis has a rare phenomenon of self-healing.
So in our tuberculosis department, oh, by the way, it is best for everyone in the hospital to call themselves tuberculosis. Don’t open your mouth or shut up and say it is tuberculosis. There is no way. After all, we are a traditional Chinese medicine hospital. We must listen to whoever eats. We still have to reflect Come out with the characteristics of traditional Chinese medicine. ”
Hehehe~~~
Everyone in the yard chuckled.
A Western medicine department has been established in a traditional Chinese medicine hospital. This is the first time this has happened in China, and everyone is quite surprised.
"At present, our tuberculosis department has temporarily admitted eight patients, two of whom are Ma Lianliang and Zhao Yanxia, both famous actors. The other eight are employees of our traditional Chinese medicine hospital. After one month of treatment, they have achieved very good results.
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Among them, Ma Lianliang's condition is more serious, reaching type II hematogenous pulmonary tuberculosis, so the course of treatment needs to be longer; while Zhao Yanxia has almost no clinical symptoms and is equivalent to an asymptomatic virus carrier. ”
At this time Bi Xinglong suddenly interrupted:
"Wait a minute, Director Lin, what did you just say about type II hematogenous pulmonary tuberculosis? What kind of tuberculosis is this? We have never heard of it before."
Lin Sanqi blinked and looked at the other doctors: "Have you never heard of type II blood-borne pulmonary tuberculosis?"
"No!"
"Is there type II and type III and IV?"
Lin Sanqi nodded: "It's true!"
Both sides looked at each other with big eyes and small eyes, and then Lin Sanqi understood that this should be caused by the information gap between the two eras. In this era, the classification of tuberculosis should not have been available, or it has not yet been formed?
Thinking of this, Lin Sanqi quietly took out a 2022 edition of "Infectious Diseases" from his backpack, turned to the fifteenth section of "Tuberculosis", and found this passage in the textbook:
"Based on the pathogenesis and clinical characteristics of tuberculosis, the Tuberculosis Branch of the Chinese Medical Association revised and formulated a new classification of tuberculosis in my country in 1998."
There are five types in total. Primary pulmonary tuberculosis (type Ⅰ), hematogenous pulmonary tuberculosis (type Ⅱ), secondary pulmonary tuberculosis (type Ⅲ), tuberculous pleurisy (type Ⅳ), extrapulmonary tuberculosis (type V).
Lin Sanqi could recite these five types of classifications, but this was the first time he knew that the original classifications were formulated decades later.
Seeing that Lin Sanqi was in a daze, Pan Ye sat next to him and gave him a gentle push:
"Everyone is looking at you, why are you in a daze?"
Lin Sanqi suddenly slapped her thigh:
"Okay, okay, okay, it's good to work with professionals. No, we can publish several papers in today's chat. For example, the research group on tuberculosis classification can publish more than ten papers."
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Then Lin Sanqi was a little worried, how could he publish his paper? These days, he didn't communicate with developed countries, and he didn't even have a way to submit his paper.
When the doctors from the two hospitals present heard the paper, their eyes widened.
Ordinary doctors only think about how to treat diseases, while doctors with higher levels only think about how to summarize the experience gained from treating diseases, or summarize the abnormal phenomena discovered in clinical practice through scientific research.
Then publish the paper.
The significance of the paper is not only that it can be remembered in history, but more importantly, it can be seen by all doctors around the world, so that everyone can learn new knowledge and new skills, and then apply them clinically to jointly promote the development of medicine.
Of course, the number of papers published and the quality of medical journals can also reflect a doctor's status in the medical community.
Each of the 20 doctors present hopes to have their own research group and publish their own papers.
Bi Xinglong asked excitedly: "Director Lin, can we set up our own research group at the Hospital of Traditional Chinese Medicine? Will the hospital allow it and will it allocate funds?"
Lin Sanqi waved her hands and shook her head:
"Don't be anxious, don't be anxious. We will definitely set up a research group, but not now, and it doesn't require the hospital's consent. As long as our department organizes it ourselves. The most important thing now is to treat diseases. In your words, it requires a large patient base. ”
As soon as these words came out, everyone calmed down.
Yes, it’s that easy to do scientific research. You need equipment, funds, and support from leaders. It’s better to be down-to-earth and work as a “wage earner.”
Yang Guang stood up for a moment, and then nine doctors including Cong Sheng, Fu Jinsheng, and Jin Yuchun also stood up:
"Please give the order, Director Lin, and we will ensure that we complete the task."
The doctor at Xiehe was very embarrassed and quickly stood up: "Director Lin, we will do whatever you say."
Lin Sanqi knew that the people in the Digital Hospital may not be convinced by him, but they were more disciplined and obedient, so they were willing to listen to his orders.
The doctors at Union Medical College Hospital were under the roof, so they had to lower their heads, wondering why they were complaining.
The establishment of trust requires a process and an opportunity.
"Okay, since we are all colleagues and senior doctors, I won't be polite.
In this way, our 20 doctors are divided into 4 wards, with 5 doctors in each ward. In a while, you will form your own team and elect a department director. I am thick-skinned and will temporarily serve as the director of the large ward.
In addition, I have 7 college students who have just been assigned here. They are both interns and department employees. Among them, Comrade Pan Ye is my fiancée. I will take care of them personally. The remaining 6 college students will be divided among the four departments.
There are also these 24 junior soldiers from our Traditional Chinese Medicine Hospital, one department is divided into 6.
This group of young soldiers is equivalent to trainees. They have no current medical knowledge and have zero basic knowledge. I also hope that you can take on the responsibility of teaching teachers and strive to enable them to become excellent medical workers. ”
The 20 overseas doctors all nodded in agreement.
Both Union Medical College Hospital and Digital Hospital have their own "medical schools", and these doctors usually take care of students, so this is not a difficult matter for them.
Yang Guang asked: "Then how will our next work be carried out?"
Lin Sanqi gestured to Pan Ye again, and Pan Ye started distributing information again:
"You should be able to operate X-ray machines, blood cell analyzers, coagulation analyzers, and biochemical analyzers, right? I don't need to hire extra people to do it, right?"
The crowd chuckled again: "Don't worry, Director Lin, we all know how to operate it. As long as we have parts, we will repair it ourselves."
Hehehe~~~
"Okay, as long as everyone knows how to operate it, it will be simple. The process of admitting patients is the same. After admission, a comprehensive examination will be carried out, and then the condition will be assessed. However, the treatment plan is different from other hospitals.
First, everyone is using this four-in-one medicine. Don’t look at it as a traditional Chinese medicine pill. In fact, the real secret inside is a western medicine. This is called ethylamine pyrazine, rifusin and smoke tablets. I combined the four ingredients into Four anti-tuberculosis drugs in one.
Taking Ethylamine Pyrazine Rifaisonium Tablets is very simple, just take one tablet a day. When the time comes, you will give the doctor's order, and the nurse will deliver it to the patient's bedside regularly every day.
In addition, the rifampicin and ethambutol in the ethamopyrazine, rifampicin, and ethambutol tablets are my personal patented drugs, and they are still in the application process, so it is best for everyone to keep them secret, and to announce to the outside that they are collectively called "Feilong Pills". Prevent research from being stolen by malicious patients.
Therefore, nurses and interns will have to work hard to watch patients swallow it with their own eyes and not let them take it out of the hospital without permission. If it goes overseas, I will suffer heavy losses and your paper will also be ruined.
Even more seriously, if our tuberculosis department can no longer run, I can pat my butt and continue to be the head of my purchasing department, while all of you here will be sent to farmers to farm and herd sheep. ”
Lin Sanqi said with a smile, but her meaning was not polite at all.
People's hearts are unpredictable, and some ugly things have to be said beforehand.
“In addition, my ethylamine pyrazine, rifaison smoke tablets also have very serious side effects, such as damage to liver and kidney function, gastrointestinal reactions, effects on the nervous system, etc.
What Pan Ye just distributed is the instruction manual for Ethylamine Pyrazine Rifusin Tablets. You can read it carefully. You are all senior doctors and should know how to identify and treat it.
Oh, regarding treatment, we must give full play to the role of traditional Chinese medicine. For example, for the most common and serious liver injuries, such as a sharp increase in alanine aminotransferase, aspartate aminotransferase, and jaundice, we can seek help from traditional Chinese medicine.
I know some of you don’t believe in Chinese medicine and think Chinese medicine is witchcraft. I don’t think it’s necessary to be so extreme. Western medicine is as good as Western medicine, and traditional Chinese medicine is as useful as traditional Chinese medicine. We must give full play to the advantages of both medicines in order to better serve patients. ”
In fact, even in 2023, Western medicine does not have particularly good liver-protecting products. Polyene phosphatidylcholine, adenosylmethionine, tiopronin enteric-coated tablets, etc. are generally used.
There are also mainstream Western medicines such as ursodeoxycholic acid, liver protection tablets, silibinin capsules, compound glycyrrhizin injection, etc., all of which are inextricably related to traditional Chinese medicine.
Therefore, Chinese patent medicines account for a large part of the liver-protecting drugs, such as Gastrodia Qufeng Tonic, Qiju Dihuang Pills, Fuzheng Huayu Capsules, Ganluoxin Pills, etc.
However, the quality of Chinese patent medicines varies. Taking many liver-protecting medicines actually increases the burden on the liver. This has also caused many people to lose trust in traditional Chinese medicine.
Now that Lin Sanqi has the best "Twelve Days of Traditional Chinese Medicine for Men", it would be a waste of talent to not use it.
When the time comes, Western medicine sterilizes, and Chinese medicine preserves health; Western medicine treats the root cause, and Chinese medicine treats the symptoms;
This is definitely the best way to combine traditional Chinese and Western medicine.
Soon, 20 doctors formed four tuberculosis wards.
Among them, the director of the first ward is Bi Xinglong of Xiehe, the director of the second ward is Cai Chunhua, the director of the third ward is Yang Guang of Digital Hospital, and the director of the fourth ward is Fu Jinsheng.
These four directors are elected by the doctors themselves, including the head nurse and director of the nursing department. This free management style is very popular among the doctors and nurses of the two hospitals.
But there is a question mark in every doctor's mind as to how good the medical skills of Lin Sanqi, director of the ward, are.
Then an accidental incident directly led Lin Sanqi to become a god in the health system and quickly established his authority.
In the master bedroom on the second floor of the Nordic Snow Country Embassy, there were violent coughing sounds... (End of Chapter)