It has been more than four years since I returned from rebirth.
In these four years, different people have different concepts.
For Wang Donglai, the past four years have been far more exciting than his previous life.
The top scorer in the college entrance examination, snatched by colleges and universities, a rising academic star, shocked the world of mathematics, won important international awards, founded a company worth hundreds of billions, was elected as an academician, and gained both fame and fortune.
The most important thing is that when Wang Donglai completed these things, he was still young.
With a mental age and social experience of nearly thirty years old, Wang Donglai took a path that ordinary reborn people would not take.
Wang Donglai dare not say how much influence he has on the entire world.
However, it also had some influence.
For example, there is the early rise of domestic smartphones and the explosion of the new energy vehicle market.
Another example is that China announced the closure of P2P platforms across the country, several years earlier than in the original history. It saved a lot of detours and avoided countless mistakes.
For example, Wang Donglai's advanced packaging design scheme has promoted the level of domestic semiconductor technology and mastered the 28nm chip process earlier.
These are only things that can be found on the surface.
Secretly, Wang Donglai has made a lot of contributions. Just like in the South China Sea incident in July, it was Wang Donglai's algorithm program that cracked the bald eagle's military communication code and found the He found the location of the Bald Eagle's aircraft carrier and forced the Bald Eagle back.
This credit will definitely not be made public, but the higher-ups will not forget this.
At this moment.
The reason why Wang Donglai is preparing to launch Changqing Liquid is because of this.
Now he has the energy to keep a golden chicken like Changqing Ye.
Even if he comes up with more disruptive products in the future, he doesn’t have to worry too much.
Previously, Wang Donglai told Zhang Bye and Zhou Rui and other Galaxy Technology executives that Changqing Liquid was developed by the company's research laboratory, which was actually a lie to them.
The research and development of a new drug takes an average of 12 years. From the final laboratory research to the final launch, on average, it takes 6.6 billion Chinese dollars, 6587 experiments, and 423 experimenters to finally get A drug.
Another data shows that in the fourteen years from 1997 to 2011, the average research and development cost of each new drug by internationally renowned pharmaceutical companies was about US$5 billion.
Just like the drug 'Gleevec', the prototype of 'Glenin' in "I'm Not the God of Medicine", from the discovery of the target to its launch in 2001, Novartis of Switzerland spent 50 years and invested more than 5 billion US dollars.
From 1997 to 2011, Novartis invested US$83.6 billion in new drug research and development, of which only 21 drugs were approved for marketing, with each new drug costing an average of US$4 billion.
It is no exaggeration to say that the birth of a new drug is completely from scratch, which is more difficult than winning the jackpot in the Chinese lottery.
From new drug project approval to product launch, the success rate is less than 2%, and other projects will naturally lose all their money.
The process from research and development to marketing of new drugs includes drug preclinical research (drug synthesis methods, extraction methods, physical and chemical properties, purity, dosage form selection, prescription screening, preparation technology, inspection methods, quality indicators, stability, pharmacology, toxicology, stability Pharmacokinetic studies, etc.), apply for clinical trial approval, conduct clinical trials (including bioequivalence experiments) research, apply for new drugs, obtain new drug certificates and drug approval numbers, conduct drug production, and post-market testing.
This set of processes is complex and cumbersome, and no mistakes can be made in every link, otherwise all the efforts will be wasted and the money invested will be wasted.
First of all, the very beginning is to find new compounds with potential, which takes two to three years, which is similar to finding a needle in a haystack.
The next step is to identify the target and synthesize compounds. In this process, researchers need to create thousands of new synthetic compounds and then screen them. Among more than 5,000 new synthetic compounds, Generally, only a maximum of 5 can enter clinical trials, and in the end, only 1 can be approved for clinical treatment of patients and become a real drug.
Clinical trial approval process is complicated and involves many departments. It requires stamps and approvals from multiple departments. You can imagine the difficulty. The failure rate at this step is almost 90%.
After passing the above difficulties, clinical trials will take another 3 to 7 years, divided into phases 1, 2, 3, and 4, mainly to confirm and reveal the effects, adverse reactions, and effects of the experimental drugs. The purpose of absorption, distribution, metabolism and excretion is to determine the efficacy and safety of experimental drugs.
After passing this level, we cannot take it lightly. Next, we need to face the approval of new drugs.
Even in the previous experiment, I felt that the new drug was very effective and there were no problems, but it still could not pass easily.
Approval However, the previous efforts still need to be reset to zero, and all the investment will be in vain.
The approval of new drugs is the most stringent and time-consuming of all processes. When submitting a new drug application, you must provide all the scientific information that can be collected. How much information is there?
Over 100,000 pages!
Due to the excessive amount of materials, if some places are not standardized, the approval time will also be lengthened.
Fortunately, it passed the approval of the new drug. After it is launched, it still needs to face supervision.
If serious adverse reactions that were not discovered in the study are discovered, the new drug will still be forced to be removed from the shelves.
Precisely because the research and development cycle of new drugs is long, the risks are high, and the investment is huge, it will go bankrupt if you are not careful.
Therefore, the number of domestic pharmaceutical companies that dare to develop new drugs is extremely rare, and the number is terrifyingly rare.
It is precisely because of this that my country has become a barren land for new drug research and development.
Except for Tu Aao’s artemisinin, there is no internationally recognized new chemical drug.
In 2013, the Tufts Drug Development Research Center announced a statistic that the R&D investment of the top ten pharmaceutical companies in the world accounted for 17.8% of sales, up to US$60.3 billion, while the top ten domestic pharmaceutical companies Pharmaceutical companies invest only 1% of sales in R&D, which is approximately US$300 million.
Everyone knows how much water there is in this 1% drug research and development.
According to a data in 2015, 95% of chemical drugs in my country are generic drugs. Even if they are generic drugs, the quality is not optimistic.
So, faced with this domestic situation.
In fact, it is no wonder that Huang Zheng, Zhang Bye and others expressed doubts about the Evergreen Liquid that Wang Donglai brought out.
Wang Donglai has known this for a long time, so he has already thought of countermeasures.
That is to push research and development into the laboratory.
The specific data is there, so there is no need to worry.
Anyone who checks it will find it to be flawless.
The emergence of Evergreen Liquid is not accidental.
Wang Donglai had obtained two magical skills before.
【Golden Finger】
[Alchemy]
These two magical skills are absolutely terrifying increases for Wang Donglai.
After acquiring these two skills, Wang Donglai was not in a hurry to show them off.
But it is accumulating silently.
Evergreen Liquid is one of the results.
Now, he thought the time had come, so he came up with the product Changqing Liquid.
In the office, Wang Donglai muttered to himself, opened the system panel, and checked his information.
[Player: Wang Donglai]
[Attributes: Physique 11, Wisdom 11]
[Occupation: Scholar, Businessman]
[Level: Level 5 (42158/50000)] [Reading types: high school compulsory courses, computers, economics, physical education]
[Skills: photographic memory, brain overclocking, insight, Celestial phenomena, preaching and teaching, living Bole, golden finger, alchemy】< br>
[Ability: sense of direction, speed reading, mental arithmetic, language proficiency, maneuvering, gifted student, memory palace]
[Subject]: Mathematics lv8 (58467/1000000), Chinese lv7 (14241/ 30000), English: lv7 (1 2142/20000), geography: lv7 (10258/20000), politics: lv7 (10010/20000), history: lv7 (11154/20000), chemistry: lv6 (14758/30000), physics: lv6 (1 4975/30000), Biology: lv6 (13472/30000), Computer: lv6 (28457/50000), Economics: lv6 (31485/50000), Sports: LV6 (8451/30000)
[Main mission: Business Empire]
[Business Empire: It is detected that the player created a company, start this mission, and the mission rewards are based on the market value of the player's company. The higher the market value, the heavier the reward. 】
[Progress: Market value exceeds 100 billion]
[Side mission: Attack of the top students! 】
[Attack of the Academic Master: Knowledge is the ladder of human progress, and books are the carrier of knowledge. Players can get one point for every one hundred books they read. 】
[Progress: 51470]
[Available points: 21]
Looking at his system panel, which had not changed much for a long time, Wang Donglai frowned slightly.
He has indeed neglected the system and his own data growth recently.
However, this is mainly because I have pushed each discipline to a relatively high level, which makes upgrading more difficult. It is no longer a simple matter of upgrading again.
After analyzing his panel information in detail, Wang Donglai closed the system panel.
……
Soon.
"I'm Not the God of Medicine" has been approved by relevant departments and has been officially released.
Because of Wang Donglai’s instructions, the plot of the movie has changed, becoming more realistic and dramatic.
Instead of choosing a prime time slot, it was released directly on a weekend nearby.
For this movie, people in the original theater chain were not very optimistic about it, and they were not interested in scheduling the film.
However, in order to achieve results, the people below finally decided to open advance screenings and invite film critics, theater directors and other relevant people to watch.
At the same time, Galaxy Technology's platforms have also tacitly promoted "The God of Medicine".
For example, Douyin, Neihan, Toutiao, etc.
As the movie trailer and promotional clips were released, it immediately caused a small discussion on the Internet.
After all, Galaxy Technology still has a certain reputation online.
But after seeing the released content, the amount of attention and discussion online gradually grew.
"Who can guarantee that you will not get sick in your life without meeting a patient? If you catch him, we all have to wait to die. I don't want to die, I want to live. Okay? ”
Among them, the video of this sick old lady with gray hair and looking extremely tired saying such lines is the most popular.
The lines are moving and the actors' acting skills are superb.
The helplessness, pain and pleading of a kind of patient are vividly interpreted.
Since then, "I'm Not the God of Medicine", which has not yet been released, has become a small hit.
“As a medical student, I dare to say that the scale of this movie is the largest in China in recent years!”
“The entry point of this movie is very good. I checked it out. It seems to be based on real events. I am looking forward to it and will buy tickets with my family to support it!”
"I can't say too much. I can only say that Galaxy Technology is awesome. It dares to invest in and release a movie like this."
"I strongly recommend everyone to watch this movie after it is released!"< br>
Comments one after another are promoting "I'm Not the God of Medicine" on the Internet, acting as tap water, and further pushing the popularity of the movie to a new level.
Soon.
Movie release.
On the first day of release, the box office exceeded 200 million!
You must know that this is the movie market in 2016, and there is a movie with a box office of 200 million in a single day.
This achievement immediately shocked the entire entertainment industry.
All the actors and staff who participated in this movie seemed to have been given a shot of blood and became extremely excited.
A few actors, especially those who have a lot of roles, are extremely active in promoting it, and even bought online for this movie, hoping to increase the popularity of this movie. .
As the box office exploded, the online reputation was even more impressive.
“There is only one disease in this world, and that is the disease of poverty. This sentence is really good!”
“Sickness without medicine is a natural disaster, medicine without money is a man-made disaster. After watching the movie, I suddenly discovered the true meaning of money. Only by making money can my family live a good life and wear nice clothes. By eating good food, you can get the best treatment and the best medicine when you are sick.”
“It’s really hard to imagine that the plot in the movie actually has real-life cases.”
< br>“I cried several times in the cinema. As a grown man, I couldn’t bear it, and tears flowed down my face.”
"I want to recommend this movie to my friends and let them all watch it!"
"I am suddenly worried now, for fear that this movie will be banned tomorrow. Such a big movie It’s unimaginable that the scale has been put on the silver screen!”
Every platform was flooded with comments about “I’m Not the God of Medicine”.
This is not a cookie-cutter rhetoric, but a genuine sentiment.
Medical, health.
This is something that many people care about and is closely related to everyone.
Seeing the plot in the movie, the audience easily got involved.
Looking at the price of 40,000 bottles of medicine in China, only a few families can afford it.
Ninety-nine point ninety-nine percent of families encountering such a disease can only wait for death after a period of time.
This further amplifies the empathy in the audience's hearts.
Subconsciously, I began to worry, what should I do if I, my family, or a relative got such a disease?
Reflected in practice, it is the strong recommendation and support for "I'm Not the God of Medicine".
So, even if it’s not a prime time period, it’s just an ordinary weekend.
Movie box office shows no sign of weakening at all. On the contrary, it is rising against the trend.
As the box office of "I'm Not the God of Medicine" is getting higher and higher, the amount of social discussion is getting bigger and bigger, and the word-of-mouth fermentation is getting faster and faster.
Soon, it attracted the attention of officials. (End of this chapter)