Chapter 100 The Dilemma of Liver Disease in the United States! (Please subscribe)
Chen Yifei, 42 years old.
Chief physician and professor of the Department of Infectious Diseases, West China Hospital, Doctor of Medicine in Liver Diseases at the University of California;
Member of the International Association of Surgery, Gastroenterology and Oncology (IASGO), member of the Sichuan Provincial Liver Disease Committee...< br>
After a tiring day's work, Chen Yifei went to the vegetable market near his home and bought a pound of shrimp, half a pound of lean meat and some vegetables.
This is his daily life. After coming home from get off work, he cooks his own meals and then waits for his wife, who is also a doctor, to come home.
Forty minutes later, boiled prawns, fish-flavored shredded pork and seasonal vegetables were served on the table. It just so happened that his wife Xu Lan also returned home.
"Director Chen, thank you for your hard work. You, a returned doctor, can cook every day. I don't know how lucky I have been in my lifetime."
The speaker was Xu Lan, who is also a tertiary hospital. An obstetrician and gynecologist, the two have been married for more than ten years and have always had a good relationship.
Chen Yifei smiled:
"Eat, Director Chen, he's just the deputy director..."
"The deputy director is also the director!"
Chen Yifei shook his head and didn't answer any more. When the rice was served, he took a few bites, and Xu Lan suddenly said:
"Old Chen "You told me yesterday that you wanted to leave Huaxi and go to the Third People's Hospital. How have you considered it?"
Chen Yifei paused while picking up the prawns. Put it in the bowl, and then he slowly said:
"After thinking about it for a day, I still want to change jobs and go to the Third People's Hospital."
Xu Lan lowered her head and did not take it immediately.
During dinner last night, Chen Yifei suddenly told her that she wanted to change jobs from West China to Chengdu Third People's Hospital.
She couldn’t believe it when she heard the news!
You know, this is West China, a hospital that many doctors dream of getting into.
After carefully asking the reason, I found out that Dean Zhou of the Third People's Hospital of Chengdu had extended an invitation to him. More importantly...
A company called Qingshan Pharmaceutical recently announced a scientific research result on the liver. , and the first clinical phase of the new drug developed as a result was placed in the Third People's Hospital.
“Is this scientific research result, or this new drug, so important to you?”
“You are even willing to switch jobs from West China?”
There was a silence. Yes, Xu Lan couldn't help but ask.
"Important, very important."
Chen Yifei put down his chopsticks and answered without hesitation.
“As you know, after returning from studying abroad, I have always hoped to make greater progress in the academic field of liver disease.”
“There are indeed many patients in West China, but in recent times, I already feel that our department is gradually lagging behind in the latest clinical research in the field of liver.”
“In other words, it is not far behind, but it is not at the forefront...
For example, it is said that three doctors are already trying to apply it to patients with liver cirrhosis, but we do not have any relevant clinical trials here. This is the gap. ”
“The ‘hepatocyte activator’ recently announced by Tsingshan Pharmaceutical is even more incomparable to ‘Ecofovir’. I think this drug can even subvert the entire field of liver disease! "
"If I continue to stay here, it will be tantamount to staying away from the world's most cutting-edge liver clinical research. "
"You know, I can't accept this kind of thing..."
Xu Lan sighed slightly. As a doctor, she can understand Chen Yifei's thoughts.
It's just...it would be a pity to leave Huaxi.
After a moment, she whispered:
"Are you sure that Qingshan Pharmaceutical's drug is really so effective? What if their research and development fails..."
< br>Chen Yifei picked up his chopsticks again:
“I have carefully learned about Qingshan Pharmaceutical. In the past few years, all the drugs they have announced have achieved great success!”
"And..."
Chen Yifei suddenly said seriously:
"And, it is no exaggeration to say that their boss Zhang Yang is not only a role model for the times, but also my idol. I believe in him."< br>
“Idol?”
“Hmm.”
...
Chen Yifei's decision was submitted to the department director the next day, and then appeared in the dean's office.
Dean Gan Weiguo frowned as he looked at the resignation application in his hand.
Although the Department of Infectious Diseases is not a star department in West China, Chen Yifei, a doctor of liver disease who returned from abroad, still attaches great importance to him.
I just didn’t expect that this doctor who had been the key to training young people would resolutely choose to change jobs, and the one he switched to was the Third People’s Hospital of Chengdu.
Of course he guessed the reason.
Chengcheng Third People's Hospital has been very popular in the past two years. Starting from "ITG human myelopoietin" to "Icofenprofovir" for curing hepatitis B, it has been the most breakthrough in China in the past few years. Both of the clinical projects were carried out in Chengdu Third People's Hospital!
Such a situation will undoubtedly attract many outstanding clinicians to join. After all, the more you are at the top clinical frontier, the more you can write high-quality top papers, and the more you can participate in the top clinical treatment plans. !
Of course, he also knows that it is not how awesome the Third People's Hospital is, but...
There is Qingshan Pharmaceutical behind it!
Thinking of this, he couldn't help but rub his temples.
Chen Yifei's job change had little impact on Hua Xi, but this kind of thing made him feel a little pressure.
"It seems that we have to spend some money to improve our relationship with Qingshan Pharmaceutical..."
...
A doctor who has the same ideas and pursuits as Chen Yifei Quite often, when Tsingshan Pharmaceutical announced that the first clinical phase of its "liver cell regeneration-promoting activating agent" would be placed in the Third People's Hospital of Chengdu, many doctors took the initiative to learn about the department's salary, recruitment status, etc. of the Third People's Hospital.
Of course, the most excited people are the liver cirrhosis patients who saw the news. Immediately, patients with liver cirrhosis from all over the country poured into the Hepatology Department of the Third People's Hospital. Everyone hoped to use Qingshan Pharmaceutical's innovative drug as soon as possible.
However.
While liver disease patients in China are rejoicing, the news has quietly spread abroad.
To be precise, it is because of the strong social influence of "Icofenprovir" that has historically cured the hepatitis B virus that all pharmaceutical companies around the world have known about Tsingshan Pharmaceuticals in a short period of time.
Therefore,
When Tsingshan Pharmaceutical announced the news of "hepatocyte activator", many well-known pharmaceutical companies around the world took notice of the news.
Reactions from major pharmaceutical companies have been mixed, with Novartis having the most intense reaction.
Novartis is one of the world's largest pharmaceutical companies. Its most famous drug is Gleevec for the treatment of chronic myelogenous leukemia.
On the third day after Tsingshan Pharmaceutical officially announced the “hepatocyte activator”, a heated discussion started in a small conference room in the Novartis headquarters building.
David Friedman, executive vice president of Novartis, is responsible for Novartis’ sales and marketing operations in the U.S. market.
The other people sitting in the conference room are:
President Mr. Green, Vice President Klein and Coles from the Institute of Drug Research.
Looking at everyone arriving, Friedman touched his unique aquiline nose, a hint of excitement flashed in his eyes.
"Mr. President, and Klein, I'm very sorry to disturb your vacation."
"But I can be sure that after you listen to my thoughts in detail, you will definitely think that everything is worth it."
President Green nodded slightly. He was on vacation in the UK and did not expect Friedman to call. Come and ask him to stop his vacation and come back quickly.
He has become accustomed to Friedman's almost paranoid character. This may be the gene in his Jewish bones.
"Friedman, it's okay, you can start.
"Okay. ”
Friedman stopped talking, pressed the button, and a clear screenshot appeared on the screen in the conference room.
He introduced:
“Everyone, this is the announcement released by the Chinese pharmaceutical company Tsingshan Pharmaceutical on its official website. They have clearly announced that they have discovered an activator that can effectively promote liver cell regeneration. ”
“As for the details of Qingshan Pharmaceutical, we learned about it carefully when they developed Icofenprovir last time, so we will not describe it here.”
Everyone nodded slightly.
Everyone is no stranger to Qingshan Pharmaceutical. This is a newly emerging Chinese pharmaceutical company with good drug research and development capabilities.
Seeing that no one spoke, Friedman pressed the button again, and another picture appeared on the screen.
“This is another piece of news.”
“Last night, the ‘animal clinical trial’ data they submitted could be found on the website of the China Food and Drug Administration. In other words, they We have indeed begun to promote the first phase of clinical trials of this 'hepatocellular regeneration activating agent'!"
"So!"
"I hope the company will talk to Tsingshan Pharmaceutical immediately. We need to simultaneously conduct FDA clinical trials of this drug in the United States."
After the words fell, the three executives present were stunned.
Immediately afterwards, President Green shook his head slightly, obviously dissatisfied.
Klein, the other vice president on the side, suddenly couldn't hold it in anymore and said:
"Friedman, isn't this the important thing you said on the phone? Right? ”
"You have already said that their drug has not yet started the first phase of clinical trials in China. Are you asking the company to talk to them now? Do you even want to introduce it to the United States to start FDA clinical trials?"
"Are you crazy? You know, any overseas drugs we introduce are only after seeing that their clinical trials in other markets have good results, at least they have reached the second phase of clinical trials..."
“Also, I don’t think they will achieve any results with this drug. After all, Gilead, GlaxoSmithKline, and even Pfizer have invested a lot in liver cirrhosis activators. Funds, but it has no effect at all."
Facing Klein's denial, Friedman's expression did not change at all, and there was even a glint of excitement in his eyes.
"Mr. President, Klein, don't worry."
"Let's close our eyes and think about it first. Think about how big our liver disease market is in the United States!"
As he spoke, Friedman didn't even wait for the three of them to react, and his voice rose one degree, and he said passionately :
“Sir!”
"We have 270 million adults in the United States. Recent statistics show that 40% of adults are obese and 18% are severely obese!"
"In other words, there are more than 50 million adults in our country. I have severe fatty liver!”
"In addition, we also have a large group of alcoholics who consume large amounts of alcohol every day.
Total, there are nearly 70 million people who have strong needs for liver disease treatment!"
"Wow. , these are shining gold Library!”
Friedman became even more emotional:
“The best thing for these people is to give up alcohol and sugar, and go on a diet to lose weight! However, no one in the United States can refuse Coke! Chicken drumsticks, burgers and a variety of milkshakes! ”
"So, gentlemen, think about it. If this drug comes out successfully, even if it has only a little effect, we can write in the hospital treatment guidelines:
You don't need to quit sugar, you don't need to lose weight. You only need to keep taking this 'liver cell regeneration activator' to enjoy a healthy liver. Guess how popular this drug will be!"
(End of Chapter)