Chapter 145 Becoming famous! (Please subscribe)
The sales volume of "Kidney Toxin Clear Dialysis Replacement Injection" in foreign markets has quickly increased. Westerners already advocate freedom and are more receptive to new things, so the promotion was extremely smooth.
Although domestic patients have low acceptance and some are worried about treatment effects, side effects and other issues, many patients have begun to try the "Kenduqing dialysis needle" under the advice of doctors.
In just one month, 103,000 prescriptions for "Shenduqing" have been issued in major domestic hospitals, and the sales volume exceeded 100 million yuan!
You must know that the current global hemodialysis market sales of consumables are US$14 billion, of which the US market accounts for the largest share, reaching 29%, totaling US$4.06 billion.
The European Union is second, accounting for 25% of approximately US$3.5 billion.
China is the third largest hemodialysis market in the world, with annual sales reaching US$2.9 billion, accounting for 20.5% of global sales.
USD 2.9 billion is equivalent to 20.3 billion yuan, which translates into monthly hemodialysis market sales of 1.69 billion yuan.
The sales of Qingshan Pharmaceutical’s “Kenduqing dialysis replacement needle” exceeded 100 million yuan within one month of its launch, which means that the market sales share of “Kenduqing” in the domestic “hemodialysis market” reached 100 million yuan in just one month. 5.9%!
The situation abroad is similar.
Ignoring GlaxoSmithKline's sales since it has not yet fully launched in the European market, the single-month sales data reported by Novartis in the United States is very gratifying.
In one month, major hospitals in the United States issued a total of 126,000 "Kidney Clear Dialysis Injections". At a cost of US$500 per injection, the sales amount reached US$63 million.
The total annual hemodialysis market sales in the United States is US$4 billion, which is about 330 million per month. Calculated,
The first month of sales of "Kidney Toxin Clearing Dialysis Needle" in the United States The market penetration rate has reached 2%!
Zhang Yang is very satisfied with such data. According to the development of the first month's sales data, he is very confident that the domestic market share will increase to 25-30% within half a year!
The foreign market should also reach a market share of about 15% within half a year. By then, the global market share of "Shenduqing" may reach 20%!
Just when Zhang Yang asked "Hehua Pharmaceutical" to increase production capacity, what he didn't know was that Lin Xiang, director of the Department of Nephrology at Chengcheng Third People's Hospital, had already begun trying to apply the "Kidney Toxin Clearing Dialysis Needle" in in non-dialysis patients.
That is, patients like young Luo Hao who do not fully meet the uremia standards, but are already in stage four kidney disease and require dialysis.
At 5 pm on September 10, the door to the classroom of the inpatient department of nephrology was closed.
Two chief physicians, four deputy chief physicians, seven attending physicians and three resident physicians from the Department of Nephrology were all present.
Director Lin Xiang stood on the podium at the top of the conference room. Behind him was a teaching screen, which was displaying the content of the cases discussed today.
Below, all the nephrology doctors, regardless of their position, were looking at the screen seriously, and from time to time they were recording in their notebooks.
“In the past month, we have tried to use the ‘Kidney Clear Dialysis Needle’ on three patients with ‘stage four kidney disease’;
The glomerular filtration rate of these three patients They are 25%, 28%, and 24% respectively, which does not meet the uremia requirement of less than 15% filtration rate! ”
< br>"According to the treatment plan in the "National Guidelines for the Treatment of Chronic Kidney Disease", the conventional plan is to first use diuretics to eliminate edema in the body, and then take hormones and nephrology drugs to control kidney inflammation while slowly draining the body's blood. The toxins in it are discharged, thereby achieving the purpose of lowering creatinine! ”
"But!"
"We are all experienced clinicians, and we all know that it is easy to remove water after taking diuretics, but it is actually difficult to reduce the toxins in the blood and the patient's creatinine. ”
“Have better luck Taking medicine can prolong the patient's life to uremia in one or two years; for unlucky patients, most patients will have their glomerular filtration rate drop below 15% after half a year and become uremic, and then they will have to undergo dialysis! ”
The doctors nodded in agreement.
At the stage of "Kidney Stage IV", the glomerular filtration rate is only 25%, and it is no longer possible to completely remove toxins from the body.
Whether you take hormone drugs or kidney-protecting drugs that lower creatinine, they can only relieve kidney inflammation and protect the kidneys, but they cannot help the kidneys complete their function of filtering toxins.
The kidneys continue to work without rest, and if they are slightly damaged again, 99% of patients will become uremic.
It can be said that once you reach the "fourth stage of kidney disease", you basically need to take some medicine and do your best to follow fate.
“So.”
Lin Xiang continued:
"I tried to use the 'Kidney Clear Dialysis Injection' on three young patients with stage four kidney disease. After one month of continuous follow-up, the results were surprising."
"Three patients The water in the body was discharged rapidly, and the blood creatinine also dropped rapidly. After the first injection, the creatinine of the three patients dropped to about 100, which means that the toxins in the body have been quickly eliminated.”
< br>“The most surprising thing is: perhaps the kidneys have been effectively rested. In combination with our hormone drugs and kidney-protecting drugs, after using 'Shenduqing' for one month, the glomerular filtration rate of the three patients did not continue to decline, but stabilized at 25% or even increased slightly. !
At the same time, important kidney indicators such as creatinine, urea, and uric acid have also dropped significantly, approaching normal!”
After the words fell, all the doctors present were stunned for a moment, waiting to see the screen clearly. After viewing the one-month tracking data presented by Lin Xiang, all the doctors were shocked!
"This...is this without dialysis? The effect achieved by just using the 'Kidney Clearing Dialysis Needle'?"
"Does this make the renal function indicators of 'Kidney Stage IV' patients almost return to normal? !”
Listening to a doctor in the audience asking in surprise, Lin Xiang He nodded and confirmed:
“Yes, I didn’t expect this result!”
“At the beginning, I was thinking about removing toxins and water in the patient’s body quickly. Excretion, thereby better protecting the kidneys for treatment.”
"After I injected the patient with two injections of 'Kidoxin Dialysis Needle', he needed to undergo dialysis according to the medication guide, but the patient did not meet the standards for dialysis."
"I tried the injection After the third injection, the effect was still very good!”
"I guess the 'Kidney Toxin Clearing Dialysis Needle' seems to help the kidneys complete 80% of the work, while the patient's kidneys, which only have 25% function, do the remaining 20% of the work of removing toxins. There seems to be a subtle balance between the two. The balance. ”
Shenduqing has completed 80% of the work!
A delicate balance!
This explanation caused all the doctors present to start a brainstorming session. After a while, a deputy chief doctor suddenly stood up and said with excitement:
"Director Lin, I think your conjecture is completely possible! ”
“According to the drug information provided by Qingshan Pharmaceutical, ‘Kidney Toxin Clearing Dialysis Needle’ can achieve 80% toxin removal effect, and It has a remarkable effect on small molecule toxins. ”
“Why do they require hemodialysis after two injections? It’s because ‘Kenduqing’ cannot remove large molecule toxins!”
"Although patients with 'Kidney Stage IV' only have a filtration rate of about 25%, they can still barely work compared to those with uremia!"
"In this way, it is entirely possible that 'Kenduqing' first filters out a large number of small molecule toxins like a nanny, and the remaining 20% of large molecule toxins are filtered by the patient's kidneys!"
Like a nanny! !
This description is very appropriate!
"Kidney Toxin Clear" will do the big head as a nanny, and the damaged kidney will do the small head. After doing it, you can have a good rest! All the doctors in the conference room immediately realized the effect of "Shenduqing". Even Lin Xiang was slightly startled, then smiled and said:
"It is true that as Dr. Gao said, Shenduqing plays the role of 'kidney nanny'!"
"So next, I plan to try to apply 'Shenduqing' to more patients." In patients with 'Kidney Disease Stage 4' or even 'Kidney Disease Stage 3'!"
"Everyone knows that 'Kidney Disease Stage 3' is a glomerular filtration rate of 30%-59%. There are no effective drugs that can control the progression of stage III kidney disease. Many patients watched helplessly as stage III kidney disease progressed to stage IV, and finally developed into uremia!”
“If the ‘Kidney Clear Dialysis Injection’ could be used in advance for patients with stage III kidney disease! , there is the word 'Shenduqing' Will the nanny's help allow the patient's kidneys to rest better, thereby preventing the progression of 'Kidney Stage III'?"
"It's completely possible!"
Lin Xiang's hypothesis instantly made all the doctors excited!
Clinically, the reason why "stage three kidney disease" continues to worsen and is difficult to control is: even if you take medicine every day to protect your kidneys and suppress inflammation, your kidneys always have to work, and 50% of the glomeruli The filtration rate gives the kidneys almost no time to rest!
How is it possible to avoid sustained injuries under high-intensity work?
Now if there is a nanny called "Ken Du Qing" to help with the work, and the kidneys can only do the remaining 20% of the work, is there still a problem? !
"Director Lin, I think this clinical topic is very good, and I request that a department team be set up immediately to start clinical work!"
"I also agree that according to this idea, the 'Kidney Clearing Dialysis Injection' may become a routine treatment method for the treatment of 'stage three and stage four kidney disease'!"
"Yes, we should start immediately. If If the patient's long-term use of 'Shenduqing' can stabilize the condition and prevent it from progressing, is it better than deteriorating to the point of requiring dialysis?"
"Yes, if it can be prevented or delayed, right? "Chronic kidney disease" will develop into uremia in ten or twenty years. How many kidney patients will it bring hope to and how many families will it be saved? I can even feel that this award will win the Nobel Prize in Medicine!"< br>
“Okay!”
Lin Xiang was very excited to see everyone’s enthusiasm. This is also the purpose of convening department doctors for a seminar today!
"Since everyone has no objection, we will divide the department into two groups and officially start the research on the clinical effect of 'Kidney Clearing Dialysis Needle' in treating patients with 'stage three and stage four kidney disease'!"< br>
As he said that, he paused!
“This requires everyone’s concerted cooperation and a large number of clinical trials and patient tracking!”
“Only in this way can we get the ‘Kidney Clearing Dialysis Needle’ that is most effective for kidney disease patients at all stages. Accurate data on dosage, medication method, etc. can provide a more accurate plan to treat every subsequent kidney patient in the future!”
"Of course, everyone in our department has a share in the results of the project, and the journals we publish will be published in the name of the entire department. Come on, everyone!"
After the words fell, the eyes of the doctors present became completely excited.
......
The task of Qingshan Pharmaceutical to develop the "Kidney Toxin Clearing Dialysis Injection" has been completed, but front-line clinicians such as Director Lin Xiang have begun new explorations.
They need to make this replacement needle, originally used for dialysis patients, more widely available to more kidney disease patients.
Of course, this is a long process.
It may take three or five years to finally form a treatment plan that is recognized by everyone in the medical community and better serve every kidney disease patient in the future.
This is the great thing about clinicians.
A week later, the Department of Nephrology of the Third People's Hospital of Chengdu suddenly published an article titled "The Feasibility of Shenduqing Dialysis Needle in Patients with Stage IV Kidneys" in the well-known domestic renal journal - Chinese Journal of Nephrology. Report".
For the first time, the report fully announced the therapeutic effects and clinical data of "Shenduqing" applied to patients with stage III and stage IV kidney disease!
As soon as the article was published, it immediately caused a strong shock in the domestic nephrology medical community!
Everyone knows that stage one and stage two kidney disease can be barely controlled!
Stages III and IV of kidney disease are almost a process of chronic progression to uremia. Kidney disease has been studied around the world for 100 years!
No medical institution or pharmaceutical company in the world can stop or significantly delay the progress of phases three and four!
No one questions it. Everyone knows that the Third People's Hospital of Chengdu is the largest clinical trial center for "Kidney Toxin Clearing Dialysis Injection" and has mastered a large amount of clinical usage data!
For a time, major domestic hospitals such as Zhejiang University, Ruijin and even Xiehe began to contact Third Person Medical, hoping to send doctors to the Nephrology Department of Third Person Medical to study and learn the clinical use plan of Shenduqing!
The news soon spread abroad,
When the Department of Nephrology of Renren Medical published the "Feasibility Report on the Application of 'Kidney Clear Dialysis Needle' in Patients with Stage IV Kidneys", it was published by the top medical journal After "The Lancet" reprinted it,
the foreign medical community, especially the foreign nephrology medical community, also caused a strong shock!
After hesitating for less than three seconds, Hopps, chief doctor of the nephrology department at the Royal Hospital in London, UK,
William, the top nephrologist at the Mayo Clinic in the United States, Müller at the Charité National Hospital in Berlin, Germany, and Li Mingyan at the National Hospital in Singapore, among other sixty-seven top nephrology hospitals, have all taken the initiative to propose I hope to have a half-month academic exchange at the Department of Nephrology, Chengdu Third People’s Hospital!
Everyone knows!
If "Shenduqing" really has a delaying effect in controlling chronic kidney disease, it will undoubtedly completely change all current treatment options for "chronic kidney disease"!
This is a historic subversion!
The feasibility report of Chengdu Third People's Hospital on the application of "Kidney Clearing Dialysis Needle" in "Chronic Kidney Disease" has completely ignited hundreds of millions of kidney patients around the world who suffer from kidney disease, as well as countless top nephrology doctors. Strong attention to Shenduqing!
Zhang Yang was still immersed in the excitement of the gratifying sales volume in the first month of the market. When calls came from one hospital after another and after reading the shocking report published by the three doctors, Zhang Yang knew that " "Shen Du Qing" is going to be popular!
A week after the news spread around the world, Tsingshan Pharmaceutical’s “Kidney Toxic Clear Dialysis Replacement Injection” has become famous in the global kidney disease circle!
Those patients with chronic kidney disease may still be waiting and watching, still doubting, but dialysis patients have completely taken action!
"Although I am already uremic, is it possible to save it?!"
Suddenly, the usage rate of kidney dialysis replacement needles began to skyrocket!
……
PS: This paragraph does not count money.
I decided not to stay up late and write during the day.
From now on, one chapter will be updated at 6 pm every day, and another chapter will be updated at 10 pm for double updates.
Everyone, take care of yourself.
(End of this chapter)