Chapter 165: sAC cyclase undergoes clinical trials!
Compared to the melon-eating masses, compared to commercial competitors such as Durex, Tsingshan Pharmaceuticals was most excited after the news spread that Qingshan Pharmaceutical had made a breakthrough in the treatment of male "asthenozoospermia"
There are still many couples suffering from infertility.
Many people have left messages before, hoping that Qingshan Pharmaceutical can pay attention to their infertility group and develop infertility drugs. Now their wish has finally come true.
In the IVF patient groups in major hospitals, everyone is discussing this matter.
"The wait has finally come. Tsingshan Pharmaceutical has really started to develop infertility drugs. I am so happy!"
"Haha! This is the best news I have heard this year. Before Qingshan Pharmaceutical has not responded to this matter. I thought... great! What a surprise!"
"Yes, sisters, we finally see some hope. I was originally prepared. I will go to the hospital for in vitro fertilization next month. Now I I decided to wait. After all, my husband has asthenozoospermia, which is consistent with the research and development direction of Qingshan Pharmaceutical.”
“I also want to wait, but... I don’t know when Qingshan Pharmaceutical will actually go on the market. ! I can’t wait any longer!”
The news that Qingshan Pharmaceutical has achieved results in male “asthenozoospermia” has excited many infertile couples, but after a short period of excitement, the real problem has emerged. In front of everyone's eyes.
Tsingshan Pharmaceutical is currently only announcing the results of research and development, and it is still uncertain when it will actually be launched on the market.
Each family’s situation regarding having a child is different. Some families can still wait, but some families can no longer afford to wait.
After two years of preparing for pregnancy, Liu Qiang and his wife were diagnosed with severe teratozoospermia + asthenozoospermia and were not prepared to wait any longer.
After their period that month, Liu Qiang and his wife prepared 100,000 yuan and went to the hospital to prepare for their first test-tube baby.
Doing IVF is not as simple as treating ordinary diseases. After completing a series of physical examinations, Xu Min started to take ovulation injections, and then she needed to come to the hospital every day for B-ultrasound to monitor ovulation.
As we all know, normal women only release one egg per month, and the follicles in the ovaries only need to mature one egg per month.
But under the action of the ovulation needle, a woman will release more than a dozen mature eggs at one time, and then the mature eggs will be removed from the woman's body through surgery.
This is egg retrieval.
Xu Min was lucky. Although the egg retrieval process was a bit uncomfortable, fortunately everything went very smoothly.
After staying in the operating room for observation for half an hour, Xu Min walked out of the operating room with a pale face.
"Honey, how are you? Are you okay?"
Liu Qiang had been waiting outside the operating room for a long time. When he saw Xu Min walking out weakly, he hurried forward with a guilty look on his face.
A warmth surged in Xu Min's heart and she forced out a smile:
"It's okay. The doctor said everything went smoothly. A total of 14 mature eggs were retrieved."
< br>“The next step is to wait for the doctor’s notification to perform the embryo transfer.”
Hearing this, Liu Qiang felt even more guilty and whispered:
"Honey, you have worked hard."
"It's okay, it's all worth it to get pregnant."
>Egg retrieval is only the first step of IVF. The next step is to artificially inject sperm into the egg to form a fertilized egg, which then develops into an embryo in culture medium.
Finally, the well-developed embryo will be transplanted into the female uterus.
Ten days later, fourteen eggs produced ten well-developed embryos, and Xu Min came to the hospital again for embryo transplantation.
Under normal human pregnancy, there is only one embryo in the uterus. In order to improve the success rate of embryo transfer, IVF usually transplants two embryos.
After the operation, lying on the indwelling bed, doctor Feng Yan came to Xu Min in person:
"The operation went smoothly, and the two cultured embryos were successfully transplanted into the uterus."
“After you go back, you have to rest in bed for three days and try not to move, so that the embryo can implant well, and remember to take medicine!”
"If there is any problem, especially bleeding, remember to come to the hospital for examination in time."
Xu Min nodded heavily, feeling very excited.
She also knows that this is the last step of IVF. If the embryo implants successfully and develops smoothly, it means success, and it means she can be a mother!
"Well, doctor, I will definitely have a good rest."
Not only Xu Min was very excited, the smooth operation also made Liu Qiang excited. The two of them swept away the previous haze and were immersed in hope. .
Xu Min specifically took leave to raise the baby at home for one or two days, but on the fifth day, a slight abdominal pain hit her, and then, some bright red blood stained her underwear.
Her heart skipped a beat.
The two hurriedly came to the Third People's Hospital of Chengdu. After informing the doctor of the symptoms of bleeding, Feng Yan's face darkened, vaguely knowing that something was wrong.
Sure enough, the B-ultrasound results came out quickly. Looking at the examination sheet in his hand, Feng Yan sighed helplessly:
“According to the B-ultrasound results, neither embryo was left. Neither implanted successfully.”
"That is to say, this test tube surgery failed."
"Does this mean it failed?"
Although Liu Qiang and his wife were mentally prepared, Feng Yan's words were still It was like a basin of cold water that directly extinguished the last trace of luck in their hearts.
It took a long while for the two of them to recover.
Xu Min forced a smile:
"Doctor, you have said before that it is difficult to succeed in a situation like ours at one time, so... we are also mentally prepared!"
"We are going to do another test tube test!"< br>
“Well, okay!”
After a brief period of disappointment, Liu Qiang and his wife quickly decided to conduct a second test-tube baby.
Thanks to the advancement of medical science, after Xu Min retrieved fourteen eggs last time and cultivated ten, the remaining eight embryos have been frozen.
If you perform in vitro fertilization again, you don’t need to retrieve eggs again. You only need to implant the frozen embryos into your body.
After IVF failure, you don’t have to wait too long for the next transplantation period. You can try transplantation again in the second month after failure.
Time passed quickly, and after having the first transplant experience, Xu Min successfully transplanted two embryos again in the second month.
This time she specifically asked for half a month's leave and lay down carefully on the bed.
The first week passed smoothly, but before the two of them could be happy, the unfortunate news came again.
The transplanted embryo fell out again and still failed to implant.
In the consulting room.
Hearing the result, Liu Qiang couldn't accept it:
"Doctor, didn't you say before the operation that the embryo was developing well? Why did it fall out after just a few days without even successful implantation? ..."
Feng Yan can understand Liu Qiang's mood.
Continuous failures bring not only psychological pressure to patients, but also financial pressure!
After a slight pause, he patiently explained:
“We do think that the cultured embryos are good, because their development and appearance are almost the same as those of normally developing embryos.”< br>
“But this is just the standard we think of. The human body system has its own set of screening judgment standards, among which During the process of laying, the human body will automatically determine whether the DNA fragments in the embryo are complete, whether the genome carried is complete, etc..."
"If the quality of your sperm is not very good, the cultured embryo will be prone to DNA. The loss of fragments can easily cause the human body’s elimination mechanism to be eliminated naturally.”
"As for these contents, with the current medical methods, we have no way to intervene manually... We can only continue to try, hoping to have a good embryo that can implant and develop!" Liu Qiang was silent for a long time, and said heavily Sighed.
In the final analysis, the quality of my sperm is not good.
Although Xu Min on the side was also very disappointed, looking at her husband who was blaming himself and feeling sad, he still forced a smile and comforted him:
"Husband, it's okay, didn't we all think about it in advance? Okay, you won’t succeed in one or two attempts!”
"We will definitely get pregnant if we do another test tube transplant."
Xu Min's encouragement cheered up Liu Qiang, but the 100,000 yuan he originally prepared had been spent after two test tube transplants.
As a last resort, the two raised another 50,000 yuan and started their third IVF attempt.
Xu Min was more careful this time, and even bought some miscarriage pills and miscarriage supplements through the recommendations of many pregnant mothers in the patient group...
One week, two weeks, three weeks week.
The situation this time seemed to be much better than the previous two transplants, but just when the two of them turned from anxiety to anticipation, fate seemed to play a cruel joke on them again.
On the twenty-first day, bleeding occurred again, exactly the same as the previous two times!
The embryo failed to implant again.
Looking at the two silent people in front of her, doctor Feng Yan didn't know what to say for a moment.
This is what IVF is like. Many infertile couples conceive children through IVF, but what many people don’t know is that
The process is so difficult and stressful that people who have never experienced it cannot understand it.
After a long while, Feng Yan sighed and handed the inspection information to Xu Min.
“I have told you many times about your situation. It is almost impossible to get pregnant normally.”
“There is a certain probability of doing in vitro fertilization, but it takes a lot of time. After three attempts, it seems that you may not even be able to get pregnant through IVF."
"I suggest you think about it carefully."
"..."
The doctor's words and the experience of three consecutive failures made the two of them completely exhausted. This time, the two of them were not as determined as before to start the next test-tube baby. They both needed to think carefully. think.
When I got home and looked at the empty room, the two of them looked at each other and fell silent. The atmosphere was horribly depressing!
Until half an hour later,
Xu Min was the first to speak:
"Husband, let's try our best one last time!"
"I heard from many sisters in the patient group that there is a Guanyin in the west of the city that is very effective in giving birth to children. Many couples who have not been pregnant for a long time go to worship Guanyin. I’m pregnant!”
“Let’s go and say goodbye before our last test tube!”
Liu Qiang didn’t believe this at first, but now he has no choice!
With the last hope, before the fourth in vitro fertilization, Liu Qiang and his wife came to the Guanyin Temple in the west of the city devoutly and worshiped the Guanyin in person.
Not only them, but even many patients in the group who had failed in vitro fertilization also came to pray for blessings, hoping that the Mother-Giving Lady could give them a child.
Perhaps it was because he worshiped the Empress who gave birth to children,
Xu Min’s fourth test-tube baby went extremely smoothly, and everything was normal until the third week after the transplant.
Xu Min even discussed it with Liu Qiang privately:
"The Queen who gave birth to a child is so clever! It is really possible that we are pregnant!"
But at the beginning of the fourth week, unfortunate news suddenly came.
Exactly the same as the first three times, still bleeding, still unable to implant, the fourth IVF failed again!
Looking at the extremely familiar B-ultrasound examination sheet, the two of them completely collapsed emotionally.
After returning home from the hospital, even Xu Min, who had always been optimistic, remained silent without saying a word.
The emotions of loss and despair spread in the hearts of the two of them. After it lasted for half an hour, Liu Qiang in the room suddenly sighed heavily and broke the silence:
"Xu Min, it's my problem. I don't want to drag you down anymore. Let's get a divorce."
Divorce?
Xu Min's heart skipped a beat and she had mixed feelings.
She raised her head and glanced at Liu Qiang, then lowered her eyes again.
Divorce, what a strange word!
She and Liu Qiang met at work and have always had a good relationship. She likes Liu Qiang's thoughtfulness, motivation and gentleness.
So, even if the first two test tubes failed, she has been encouraging Liu Qiang not to give up!
But at this moment, she also fell silent.
She loves Liu Qiang and she loves this family, but she also wants to be a mother and give birth to a lovely child!
Unknowingly, Xu Min's tears suddenly flowed down.
Seeing Xu Min's tears, Liu Qiang couldn't help crying.
"Honey, I'm sorry for you, it's my problem. I don't want to drag you down, you are still young..."
"Husband! I don't want to divorce, I don't want to leave you!"< br>
"God, why is it so easy for others to get pregnant and so difficult for us? Why don't you give us a child, Lady Sangzi?!"
The hoarse voice echoed in the room. , Xu Min's sudden emotional outburst made the two of them hug each other and cry!
They have worked really hard!
They really have tried their best!
Traditional Chinese medicine, in vitro fertilization, and even hope to give birth to a baby!
But there was no result!
The two hugged each other and cried, vaguely guessing each other's ending!
divorce.
I don’t know how long they cried. Their emotions gradually calmed down, but the real problem was once again placed in front of them.
No children, divorce?
Xu Min didn't want to think about this, so she subconsciously glanced at the patient group on her phone, and 99+ messages appeared in front of her.
When I clicked on it, a shocking news suddenly appeared in front of me!
"Tsingshan Pharmaceutical's 'sAC Cyclase Male Sperm Activator' has officially started clinical trials, and now recruits a large number of men with asthenozoospermia to participate in the trial!"
Tsingshan Pharmaceutical?
Asthenospermia? !
Xu Min looked startled, and then his eyes flashed with an astonishing look!
“Husband, do you remember Qingshan Pharmaceutical?”
"The drug they announced before to treat 'male asthenozoospermia' seems to have started clinical trials!"
(End of Chapter)