Chapter 182 Durex, do we want to fight back? (Please subscribe)
Qingshan Pharmaceutical.
After having fun with Zhou Xiaomei during the noon break, Ren Xiaomin came to Zhang Yang's office just after going to work at two o'clock in the afternoon.
Unexpectedly, the first thing I talked about was the "Male Essence Strengthening Oral Liquid".
“Zhang Yang, our ‘Qiangjing Guben Oral Liquid’ has only two or three days left to complete the Phase III clinical trial. Judging from the current results, our probability of passing the clinical trial is very high, and it is basically a sure thing. .”
"My colleagues in the market research department have also completed various market research before the drug is launched, and the preliminary pricing plan has been handed over to me. When will you have time to take a look?"
After the words fell, Zhang Yang said Only then did he notice that Brother Ren was holding a piece of paper information in his hand.
With the rapid development of Qingshan Pharmaceutical, the company's scale is getting larger and larger, and Zhang Yang can no longer put drugs on the market by estimating a rough price as before.
Tsingshan Pharmaceutical has established a special "Price Strategy Department". Professional colleagues first conduct research and analysis on the market demand for innovative drugs, competitive products, etc., and finally issue a detailed pricing strategy.
Such an approach will undoubtedly make the pricing of each drug of Tsingshan Pharmaceutical more reasonable and commercial.
Of course, the final price of each drug still has absolute pricing power!
“Okay Brother Ren, let me take a look.”
Zhang Yang immediately took the pricing information from Ren Xiaomin’s hand and started flipping through it while Ren Xiaomin explained in detail:
“The marketing department’s pricing plan is mainly based on drug effects, drug taking cycles, and market competition. It is considered from the four dimensions of product and drug cost.”
“Let’s talk about the effect first. This time, we have recruited a total of 740 patients in the first, second and third phases of the ‘Qiangjing Guben Oral Liquid’ clinical trial. Excluding 50% of the control group, 370 male patients actually took the drug. ”
"After 3 months to half a year of clinical medication, 74% of the 370 subjects saw their sperm activity increase from less than 3% initially to 12%, reaching the minimum medical requirement for normal male sperm activity. "
" For another 26% of patients, although their sperm activity still did not meet the target, it also improved to the 7-10% range. "
"It can be said that the overall effect is very good."
Zhang Yang nodded in approval.
Whether a man’s sperm quality is good depends on sperm activity and sperm deformity rate.
Qiangjingguben Oral Liquid is only designed to improve sperm activity. It can significantly improve sperm activity and return it to normal, which is enough to be called a significant effect.
Ren Xiaomin continued:
"As for the medication period..."
"Actually, our original idea of taking the medication was to take the medication for at least three months, because the laboratory data It takes three to six months of long-term use for male sperm activity to gradually return to above 12% and return to normal.”
“But as you know, many subjects actually became pregnant after just one or two months of use. Having a baby..."
Saying that, Ren Xiaomin couldn't help but paused, and said with a smile:
"I have to say that the human body is really amazing. 12% is just a medical standard. In fact, many patients have 6% or 7% of their sperm. Activity, as long as the frequency is a little more frequent, you can still get pregnant.”
“So... judging from the data collected by our entire clinical trial, the subjects. The pregnancy cycle is far shorter than the cycle for sperm activity to return to normal. The average cycle from taking the medicine to pregnancy is only two months and one week. "
"So, colleagues in the price department calculated the average for each patient. The medication cycle is set at two months and one week, which coincides with the pregnancy cycle. I think it is more reasonable."
Zhang Yang thought for a moment, then nodded.
He had noticed before that patients taking "Qiangjing Oral Liquid" were different from patients with traditional diseases.
Traditional disease patients are judged by whether their biological indicators have returned to normal, while the only criterion for patients taking "Qiangjing Oral Liquid" is whether they are pregnant.
If someone is pregnant, even if the sperm activity is not up to standard, who still needs to take medicine.
“The third aspect is competing products.”
Ren Xiaomin continued:
“Currently, there is no similar type of drug on the market that can improve male sperm activity, so we are unique.”
“If we have to talk about competitors, in vitro fertilization can barely be regarded as our competitor. Ordinary first-generation test tubes About 20,000 to 30,000, and the second generation is about 30,000 to 50,000.”
“However, it also includes some other medical services, and its price can only give us a reluctant reference.”
“The last one is the cost of drugs.”
< br>Hearing this, Zhang Yang's eyes also fell on the cost area corresponding to the plan.
"Because our 'Qiangjing Guben Oral Liquid' is an oral liquid in a glass bottle, the cost is higher than that of tablets. The cost of each medicine is about 6 yuan, but this is only the production cost."
< br>"In the process of research and development, we also invested a lot of money and labor costs. Of course, since this drug was completed under your leadership, we saved a lot of research and development expenses, but the cost of biochemical experiments and The cost of animal experiments is still a lot, and the total research and development costs have reached 560 million yuan."
"This money must be included in the cost."
Zhang Yang nodded again, indicating to Ren. Xiao Min continued:
“So, after comprehensive calculation, the ‘Price Strategy Department’ gave a price of 800 yuan per box.”
"800 yuan per box?"
"Well, according to normal conditions, patients need to take four boxes per month, each box costs 800 yuan, and the monthly cost is 3,200 yuan."
"Based on normal conditions Calculated by the median number of people who can get pregnant after taking it for two months and one week, a patient can get pregnant after taking about 9 boxes, which costs 9*800 yuan. A patient’s expenditure is about 7,200 yuan.”
“This is equivalent to the cost of one artificial insemination, which I think is acceptable.”
“Of course, this is the median situation, if the patient is unlucky. If you are still not pregnant after taking it for two months, you need to continue taking it for three to six months to allow the sperm activity to return to the normal value of 12%. ”
"But even if it's six months, 24 boxes, it's only 19,000 yuan, it's still acceptable."
"Yeah."
Zhang Yang hummed and had to say, This is professionalism.
With complete market data and competitive product analysis, the price is very reasonable.
But this was not over yet. As he spoke, he had already noticed the next element of the plan - the payback cycle.
Based on the fact that there are currently about 50 million infertile families in China, of which men account for 40%, there are about 20 million men with male problems.
50% of men have problems with sperm activity, which means there are 10 million potential male patients.
The plan gives a very bold prediction. It is expected to sell 2 million boxes in the first year and treat no less than 200,000 male patients.
Based on the calculation of 800 yuan per box, the annual sales amount can reach 1.6 billion yuan!
After all, just half a year is enough for Qingshan Pharmaceutical to recover its research and development costs, and the rest is pure profit.
The huge profits made Zhang Yang excited, but he also knew that the cost, especially the reason why the research and development cost was so low, was because the "Qiangjing Guben Oral Liquid" was quickly developed by himself using the energy points in the simulator. of.
In reality, it is just some scrap work and animal experiments, etc. Otherwise, there would be no such high profits.
And.
These profits must also support the research and development funds for other innovative drugs at Qingshan Pharmaceutical Drug Research and Development Center. Only when other innovative drugs have results can he exchange them for energy points in the simulator to obtain more drugs.
This is the cycle.
Thinking of this, he was very satisfied with the price and basically agreed in principle.
But after a moment, he suddenly looked at Ren Xiaomin and said:
"By the way, Brother Ren, didn't anyone from the National Medical Insurance Bureau contact you?"
Ren Xiaomin was stunned. After a moment, he reacted immediately.
Under normal circumstances, once Tsingshan Pharmaceutical develops a new drug with good effects, even if the clinical trial has not been completed, people from the National Medical Insurance Administration will come in advance to understand Tsingshan Pharmaceutical’s price positioning of the new drug, which is convenient A subsequent decision will be made as to whether to include it in medical insurance. This can be regarded as a small tacit understanding between each other.
This time, "Qiangjing Oral Liquid" is about to finish clinical trials and apply for production approval. Colleagues from the Medical Insurance Bureau haven't come to give it a try, which is obviously due to lack of interest or no intention to include it in medical insurance.
He then smiled bitterly and said:
"Zhang Yang, the Medical Insurance Bureau should not include this drug in the medical insurance list."
"Come on. After all, medical insurance does not even include in vitro fertilization (IVF) reimbursement; secondly, the issue of not being able to have a child is not very universal, and most families can still have normal children.”
"According to the current medical insurance policy, we still hope to use more medical insurance funds on life-saving drugs and increase the reimbursement ratio of life-saving drugs and chronic drugs."
Zhang Yang thinks about it too.
And to be honest, "Qiangjing Guben Oral Liquid" can be regarded as a one-time drug and does not need to be taken for a long time. Calculating this, it costs 10,000 to 20,000 yuan to have a child, and most families can afford it at their own expense.
Not a big problem.
But just as he slowly closed the final plan and put it back on his desk, Ren Xiaomin suddenly changed the topic and continued:
“However, although domestic medical insurance does not pay much attention to this oral solution, our neighbors seem to be somewhat interested.”
“I received a business letter from South Korea’s Samsung Biotech a few days ago. They asked Is it possible for us to cooperate and introduce this drug to South Korea? "
"Korea? Samsung Biotech?"
Zhang Yang raised his eyes in surprise.
“Yes, it’s South Korea, it’s Samsung Bio.”
Ren Xiaomin confirmed:
“I carefully confirmed the business letter, it is Samsung Biologics, a subsidiary of Samsung Group.”
“They were founded in 2011. Over the years, they have cooperated with global companies such as Pfizer, Novartis, and GSK. Well-known multinational pharmaceutical companies have reached a number of cooperation. They want to introduce our 'Qiangjing Oral Liquid' and probably hope to improve some Korean products. Fertility rate. ”
“You may have heard that South Korea’s fertility rate is the lowest in the world. On the one hand, young people’s desire to have children is declining, and on the other hand, men’s sperm quality is reduced and they cannot have children. ”< br>
“If our oral solution can be introduced, it will give Korean men more possibilities to have children anyway.”
After hearing the end, Zhang Yang smiled bitterly.
It would be normal if the Samsung Group wanted to introduce the "Strengthening Essence Oral Liquid". The Samsung chaebols are eager to have more cows and horses in the country.
Even, not only South Korea, but also countries with declining birthrates and low fertility rates are expected to introduce "Qianjing Oral Liquid" in the future.
However, Zhang Yang did not continue to struggle with this matter. After thinking for a moment, he said:
"Okay Brother Ren, you will be directly responsible for this matter. I must have agreed to sell it overseas. As for the export price from South Korea, we can negotiate again at that time.”
"Okay."
After solving two things in one go, Zhang Yang originally thought that this meeting and exchange would be over.
Unexpectedly, Ren Xiaomin not only had no intention of leaving, but after taking a sip of tea, his face suddenly changed and his voice suddenly dropped:
"Zhang Yang, there is one more thing. Something happened!”
“Do you remember that after we launched the sAC male contraceptive pill, there was an inexplicable voice on the Internet criticizing the contraceptive pill that we should not develop?”
Zhang Yang also looked startled, and then the memories from two months ago quickly came to his mind.
He remembered that he had determined that someone was buying the male contraceptive pills from Qingshan Pharmaceutical on the Internet, and he even guessed that it might be a condom manufacturer!
He said anxiously:
"Brother Ren, have you found out who it is?"
Ren Xiaomin nodded heavily!
Zhang Yang's breathing involuntarily accelerated by two minutes. Although the person behind it did not cause any specific harm to Qingshan Pharmaceutical, it was so disgusting!
“Who is it?!”
“Durex!”
“It’s really him!”
Zhang Yang frowned, not too surprised .
China is the world's largest condom market, and Durex is the best-selling condom brand in the country. The launch of Qingshan Pharmaceutical's male contraceptive pill will inevitably cause Durex's sales to decline. It's strange that they don't worry!
I just didn’t expect to use such a shady method.
"Brother Ren, how did you know it was Durex?"
"Haha."
Speaking of this, Ren Xiaomin suddenly laughed, and Zhang Yang was suddenly confused.
He explained:
“It’s a coincidence, you still remember the big medical V who hacked us the most on Weibo, right? His name was Liu Zhiyuan.”
“Your name was When I was investigating him, I read his information carefully, so I was very impressed; a few months ago, when the list of patients for the Phase III clinical trial of 'Qiangjing Oral Liquid' was transferred to me for signature, I accidentally noticed this name!"
"After checking, I didn't expect it! It’s really him!”
Huh?
Zhang Yang couldn't help but be stunned:
"You mean this big V who is teasing us came to participate in the Phase III clinical trial of our 'Qiangjing Oral Liquid'? He can't give birth to a child either? Does he have asthenozoospermia? ”
“Hmm!”< br>
Ren Xiaomin couldn't help but laugh:
"His wife is nine years younger than him, and she loves her very much. However, she never got pregnant after getting married. After an examination, we found out that he has severe asthenozoospermia. ”
"I have read his test report. The sperm activity is only 1%, and there are almost no sperm moving forward. Even in vitro fertilization may not be successful!"
"His wife found out and wanted a divorce. He had no choice but to secretly come to Chengdu to apply for participation in our Phase III clinical trial!”
“I noticed this!”
Zhang Yang found it funny. But soon huge doubts appeared in my mind.
“Brother Ren, how do you understand the details so clearly!”
"Haha! Because I contacted him by phone immediately after knowing it and refused him to participate in our Phase III clinical trial!"
"In desperation, he told me everything, including finding him The financial backer is Durex’s business!”
Huh.
Zhang Yang exhaled, it turned out to be like this.
Gradually, his thoughts focused on Durex.
"Brother Ren, do you think we should fight back?"
(End of this chapter)