Chapter 196 The plan has changed and must be reported
Making up his mind, Zhang Yang submitted an application to the P3 Laboratory of the Centers for Disease Control and Prevention the next day, applying to provide a large number of "pneumonia virus" samples again.
At present, he has only isolated the "T14-specific protein" from the "pneumonia virus", but he does not understand the specific mechanism of action and protein characteristics of the "T14-specific protein" in the virus.
So the next step is to isolate more "T14-specific proteins" from the "pneumonia virus", and then conduct in-depth analysis of the proteins to find ways to find compounds that can remove the "T14 protein" .
What needs to be noted here is that
Although Zhang Yang completed the pathway research on the "T14-specific protein" in the simulator, there is a difference between the "T14-specific protein" carried in the virus and the "T14 protein" in the "lung adenocarcinoma cells" that has completed inducing carcinogenesis. Different.
Needs to be re-researched.
However.
At ten o'clock in the morning the day after he submitted his application, when he came to the laboratory after handling company affairs, Team Leader Huang Qihuang had been waiting outside the P3 laboratory for a long time.
“Team Leader Huang, morning!”
Outside the P3 laboratory, Zhang Yang immediately noticed Huang Qi, who was standing at the door of the laboratory with a bright head.
"Mr. Zhang, it's ten o'clock, so it's not too early."
As he spoke, he paused:
"I have something I want to talk to you about. Let’s chat, can you take a step to talk?”
“Huh?”
Zhang Yang was slightly startled.
To be honest, the relationship between him and Huang Qi is not bad. They even greet each other politely every day when they meet.
But he knew very well that the friendship between the two parties was only at work, and was far from being acquaintance.
Soon, he reacted:
“Is it about my application for a ‘pneumonia virus’ sample yesterday?”
"Yeah."
Huang Qi nodded.
Seeing this, Zhang Yang also stopped entering the laboratory, and then followed Huang Qi to the office.
As soon as he sat down on the chair, Huang Qi did not hesitate, subconsciously touched the top of his bald head, and then went straight to the point:
"Mr. Zhang, I remember when you applied to use the laboratory. At that time, the application was based on studying the pathological mechanism of 'pneumonia virus' and developing a drug that can treat 'pneumonia', right?"
"Huh? What's wrong?"
"Nothing!"
Huang Qi stared at Zhang Yang:
"I saw the application you submitted yesterday. Time has provided you with a sufficient number of 'pneumonia virus' samples. It hasn't been long now, right? Do you need more virus samples?"
"Also, the virus samples you applied for this time? Is the quantity too much? ”
Is it too much?
After the words fell, Zhang Yang felt a chill in his heart.
In fact, the virus samples in the laboratory are different from the viruses circulating in the air.
Laboratory virus samples are usually cultured from animals or cell culture dishes with extremely high purity.
Viruses in the air or circulating outside are often mixed with various droplets, dust, microorganisms and other chemicals, which will lead to certain deviations in experimental results and analytical data.
Therefore, all relevant research uses higher purity virus samples to ensure the accuracy of the research.
In addition, the virus samples in the laboratory are not stored one by one, but are mostly stored in the form of "virus liquid".
When necessary, the researcher takes out the "virus liquid" and dilutes or concentrates it to determine the required amount of virus.
For basic research on virus samples, such as studying the replication mechanism and gene sequence of "pneumonia virus", the required virus samples generally only require about 1 ml.
Only when there is a huge demand for virus samples when a large number of animal experiments are required for vaccine and drug research and development in the later stages, a large number of virus samples will be applied for.
This time, Zhang Yang is not only preparing to isolate a large amount of "T14-specific protein" from the "pneumonia virus" for analysis and research, he is also preparing to culture the "T14 protein" in cells to speed up the research and development progress.
In this way, a large number of virus samples are needed.
After thinking for a moment, Zhang Yang raised his head and said seriously:
"Team Leader Huang, it's like this. I have completed the basic analysis of 'pneumonia virus'. Next, I am going to conduct cell culture and animal testing. Experiment, so... the number of virus samples requested is larger."
"Huh?"
"Have you completed the analysis of the 'pneumonia virus'?"
Zhang Yang's words made Huang Qi slightly stunned. He had not expected this answer.
After a moment, he frowned and said in a deep voice:
"Why so fast? I remember it was only about ten days before you really started analyzing the virus, right?"
After the words fell, Zhang Yang's heart skipped a beat.
Huang Qi's words are correct. Although it has been a month since he entered the P3 laboratory, he spent the first half month getting familiar with the experimental equipment and experimental procedures. It has only been in the past ten days that he has really started to isolate the "T14-specific protein"!
It’s just...
Why does Huang Qi know so well?
Have you been paying attention to the progress of your experiment?
Suddenly, a strong sense of vigilance suddenly arose in his heart, but his expression did not waver at all, and he even smiled:
"Team Leader Huang, I have not been conducting virus analysis for a long time!"
"But I have indeed completed the preliminary 'virus analysis' and am preparing for cell culture, so I need more virus samples."
After getting Zhang Yang's affirmative reply again, Huang Qi was silent for a few seconds this time.
After a while, he spoke again:
"Okay, Mr. Zhang, I understand!"
"Since you are ready to start animal experiments, I will submit your application to the virus database. If everything goes well, you will be able to get the virus sample tomorrow."
A smile appeared on Zhang Yang's face again:
"Thank you. If there is nothing else, I will go into the laboratory. I have an important experiment to complete today."
"Okay! You are busy!"
After the interlude, Zhang Yang walked out of Huang Qi's office.
After completing a series of disinfection procedures and entering the P3 laboratory, the bright smile on his face gradually disappeared, and a stronger alert arose in his heart.
At this moment, he suddenly felt like he was being targeted;
For the first time, he thought of the decision he made with Ren Xiaomin a few days ago!
"No! The previous idea was too risky!"
"Although I had thought that Huang Qi might discover the secret of the 'T14 protein' before, I thought it would be possible to hide it secretly! ”
"But now Huang Qi is obviously extremely concerned about the progress of his experiment. He even knows that he only spent ten days analyzing the 'virus'!"
"The next step is to isolate and cultivate the 'T14 protein' in large quantities. ', Huang Qi is so concerned, it is absolutely difficult to guarantee that he will not be discovered!"
"As Brother Ren said, once the secret of the 'T14-specific protein' is discovered, it will be difficult for me to explain it clearly!"
While thinking, Zhang Yang slowly sat in front of the experimental table.
For a long time, a glimmer of light flashed in his eyes, and he had other plans in mind. "It seems that this matter cannot be completely concealed. It must be reported, at least in advance!"
“Otherwise, I will never be able to explain it when the ‘T14 protein’ is discovered!”
“It’s just...”
“It’s just that the previous idea was not complete. No! Once reported to the CDC headquarters, there is a high probability that the news will be leaked!"
"The best way is..."
"Report to the National Security Bureau?"
Soon, Zhang Yang rejected the idea.
National Security mainly targets intelligence. I am afraid that they are not too familiar with this highly professional medical risk, and the process of understanding it is very likely to be leaked.
So,
the safest way is...
Directly contact a big person who can really control the overall situation, and then tell them all about your discovery and your next plan to develop a drug that can clear "T14 protein"!
In this way, not only do you no longer have to take any risks, but you also don’t have to worry about the possibility of the news being leaked!
Even, with the response plan provided by himself, the big man should be able to deal with this matter with a more stable mentality and take control of it!
"Yes! That's it!"
Zhang Yang nodded, his thoughts becoming clearer.
But who is this big shot looking for?
Zhang Yang’s mind was racing, and blurry characters flashed before his eyes one after another.
He has been a role model of the times before, and has won many honors such as the National Outstanding Youth and the May 1st Labor Medal. He has also met many great leaders.
CDC, no.
Medical Insurance Bureau, no.
Health Commission, no.
Suddenly, an old man flashed in his mind.
Two days later, Zhang Yang came to the capital in person with the compiled information and a travel bag.
After waiting all night, he took a plane back to Chengdu the next day, but his travel bag was empty and the virus information he carried was missing.
The short two-day trip to the capital allowed Zhang Yang to completely let go of his psychological burden, and the other party’s reply only included a few sentences:
First, we promise to immediately arrange for professionals to carefully verify this matter.
Second, I hope Zhang Yang will continue to speed up the research and development of drugs to eliminate "T14 protein".
Of course,
Zhang Yang still knows very well that although the relevant information about "T14 protein" has been reported, all research on "T14 protein" must still be highly confidential. Once the news is leaked, , it will undoubtedly be very troublesome!
In the following days, Zhang Yang was still very cautious. While isolating a large amount of "T14-specific protein" from the "pneumonia virus", he cautiously carried out analysis and research on the "T14 protein".
Thanks to his previous experience in studying the "T14-specific protein" in lung adenocarcinoma cells in a simulator, Zhang Yang's research on the "T14 protein" in the virus was very fast!
A week later, he began to try cell culture for the "T14-specific protein" to obtain more basic information!
Zhang Yang’s idea is simple.
After the medicine simulator was upgraded to version 2.0, a function was added that can use energy values to accelerate drug development.
The "Qiangjing Guben Oral Liquid" of Qingshan Pharmaceutical was quickly developed using hundreds of energy points.
Similarly, this time, time was urgent and the task was heavy, so he decided to use this function to quickly produce a granule that can remove "T14-specific protein".
It’s just that the “T14-specific protein” does not have any previous research data. Before using this function, he needs to provide the simulator with the initial protein structure and mechanism of action of the “T14-specific protein”.
Moreover, the more relevant protein information, the better. The more information you have, the faster you can find the best target!
Now, what he is doing is collecting a large amount of "T14 protein" information for the simulator!
In this way, Zhang Yang spent almost the whole day in the P3 laboratory for the next week.
And just when Zhang Yang was devoting himself to research and development, Huang Qi appeared in Director Cao's office again.
"Director Cao, are you free? I have something new to report to you!"
Seeing Huang Qi walk into his office, Director Cao stopped what he was doing.
"Team Leader Huang, what's wrong? Is there anything new?"
"It's Qingshan Pharmaceutical's publicity about Mr. Zhang!"
"Huh?"
Hearing this, Director Cao suddenly felt a headache. He remembered that Huang Qi had specifically talked to him about Zhang Yang's use of the laboratory not long ago.
But soon, he simply stood up, poured a glass of water for Huang Qi, and said:
"Okay, tell me what happened this time?"
"Yeah."
Huang Qi took the paper cup and said:
"Director Cao, more than a month ago, when Zhang Yang first entered the laboratory, he applied for a virus sample, about 1ML."
"Previous A few days later, he applied for a 'virus sample' again, and this time the amount requested reached 5ML."
"If it is just for virus analysis, there is no need to use so many virus samples!"
“Oh?”
Hearing this, Director Cao suddenly laughed:
"Huang Qi, I remember when you came to me last time, you said it was strange that Zhang Yang spent more than ten days getting familiar with the experimental equipment. Now he has started to conduct virus experiments. "What do you think is wrong?"
Huang Qi ignored the smile in Director Cao's words and said seriously:
"Director, I have communicated with Zhang Yang, and he has personally confirmed that they have completed the analysis of the 'pneumonia virus' and are ready to start cell culture and animal experiments!"
"In just ten years How many days did they complete the 'virus analysis'? I think it was too fast! "
Director Cao smiled noncommittally.
But just when he wanted to say that Zhang Yang was a genius, Huang Qi continued:
"Not only that, this week, I carefully checked the laboratory instrument data and experimental records. Asked the two assistants assigned to him"
"Zhang Yang is indeed proceeding. Cell culture, but what he cultured in the cells did not seem to be the 'pneumonia virus', but some other viral substance isolated from the 'pneumonia virus'!"
"What substance is it specifically? The assistants have no idea that all strains were isolated by Zhang Yang himself!”
"The most important thing is that Zhang Yang did not record the separated substance in the experimental records! No one knows what he extracted!"
After the words fell, even Director Cao's expression changed slightly. .
P3 laboratory is a high-risk laboratory, and all experimental processes and steps need to be recorded.
Details include virus inoculation volume, cell type, observation time, test results, etc.!
The purpose is not only to ensure the accuracy of the results but also to trace the source!
"So, Director, I think we need to find out what Zhang Yang is doing!"
(End of Chapter)