Chapter 229 Let’s fight side by side! (Please vote for me, please subscribe!)
cure?
Acute myeloid leukemia?
Zhang Yang couldn't help but get excited. As early as six years ago, when Tsingshan Pharmaceutical launched "ITG human myelopoietin" to cure aplastic anemia, he had learned about leukemia by the way.
Of course he knows that "acute myeloid leukemia" is the most malignant among the many types of leukemia, and there is no drug that can effectively control it!
The only way is to kill the leukemia cancer cells through chemotherapy and complete the bone marrow transplant as soon as possible!
Therefore, when he handed over all the information on "ITG human myelopoietin" to the first project team, he also hoped that they could use it to develop drugs that can cure or control leukemia!
Unexpectedly, in just a few years, the first project team actually found a target related to "acute myeloid leukemia".
But after getting excited, he immediately thought of what Wei Tian said just now: In thousands of experiments, all "leukemia cancer cells" accidentally happened twice.
Then he nodded heavily and agreed:
"Wei Tian, you have done a good job. Now it is really necessary to gather the R&D backbones for an all-out sprint!"
"As you just said, although we are already certain that we can develop drugs to control 'acute leukemia', since we have discovered that there was an accident in the experiment, we must do everything we can to find out this one thousandth There is no doubt that our ultimate goal is to completely cure 'acute myeloid leukemia'!"
As he spoke, he paused specifically:
"Don't listen to what is said on the Internet, which medicine should be taken for a long time to be a good medicine; I don't have such an idea, not now, and never in the future!"
"Our Qingshan Pharmaceutical is no less good at this!"
"Yeah."
Wei Tian and Dr. Zhou looked happy.
At this moment, Zhang Yang's excited heart calmed down, and he suddenly thought of the message Director Hu had just sent to him.
Soon, he thought about drug simulators.
Since the last update of the simulator from version 1.0 to version 2.0, version 2.0 has added a "drug rapid simulation function", which allows you to quickly screen out more effective organic compounds and related targets by paying a certain "energy value" .
"Do you want to intervene at this time? Use the simulator to quickly complete the research and development of this leukemia drug?"
The idea first came to mind, but he quickly threw it away.
First, after the last rapid simulation to develop "Fei Du Qing Granules", the energy value in the simulator was only over 240 points;
With this energy value, it would be difficult to simulate and screen out meaningful compounds and precise targets. Even if there is a slight breakthrough, it will not be of great significance.
Secondly,
In the simulator version 2.0, there is also a function that can obtain energy value by selling drug patent data.
He remembered that he had shared the "sAC male contraceptive pill" independently developed by Qingshan Pharmaceutical to the simulator. It was eventually rated as a C-level auxiliary drug and he exchanged a total of 300 energy points.
Later, he specifically checked and found out that the rarer the drug, the more it treats severe and terminal diseases, the higher the score, and the more energy it can be exchanged for!
And there is another thing, the energy value of the shared drug patent will be higher if it is not exchanged with the help of the simulator!
In this case, since the drug for treating leukemia has made breakthrough progress anyway, it is better to just let the first project team develop it normally.
Thinking of this, he raised his head slightly and looked at Wei Tian.
Oh, by the way, there is a more practical question!
Wei Tian has now mobilized the R&D backbone of the entire drug R&D center. It would be unsightly for him to intervene at this time!
Zhang Yang had made up his mind, but he had no intention of staying out of the matter completely.
After looking at Wei Tian, his eyes finally fell on Dr. Zhou and said in a deep voice:
"Zhou Bo, I have a request."
"I also want to join our research and development team, and I also want to contribute to this leukemia drug."
Zhang Yang originally thought that his request would not be rejected, but as soon as he finished speaking, Dr. Zhou suddenly looked slightly stunned. After hesitating for a moment, he hesitated and said:
"Mr. Zhang, you...you also want to join the R&D team?"
"Yeah."
Zhang Yang nodded, and then noticed the inexplicable hesitation and dodge in Dr. Zhou's eyes.
At this moment, Wei Tian on the side showed a wry smile and said to him:
"Boss... you are usually so busy. If you want me to tell you, just leave it to Dr. Zhou and the first project team!"
"Besides, I have mobilized almost all the top researchers in the R&D center, and Dr. Zhou has also laid out all the R&D plans. Don't worry, I believe there will be significant progress in three to five months."
"If there is no breakthrough by then, how about you join again?"
Zhang Yang was so smart. Seeing the evasion and hesitation in Dr. Zhou's eyes, and listening to Wei Tian's polite words, he instantly understood the subtleties.
Firstly, this is because he is afraid that after joining the R&D team, he will forcibly interfere in the R&D project and disrupt the original R&D plan.
Secondly, from Dr. Zhou’s perspective, who wouldn’t want to be the independent R&D leader of this drug that will surely go down in the history of human medicine?
Even if you leave Tsingshan Pharmaceuticals in the future, you can become a leader in the field of leukemia drug research and development with this resume!
Zhang Yang smiled and didn't point it out.
He looked at Dr. Zhou, and then pointed at the R&D personnel who were registering in the meeting.
"Zhou Bo, don't worry, I just want to be a part of this drug development like them and do my part for this drug!"
"I will not interfere with your R&D progress and projects."
Dr. Zhou's face suddenly turned red and he said hurriedly:
"Mr. Zhang, that's not what I meant..."
"Your status and reputation in the field of drug research and development are self-evident. If you give us some guidance, our leukemia drugs may progress even faster!"
"I'd love for you to join in."
Zhang Yang smiled and shook his head:
"Zhou Bo, I am serious! I believe in your ability and the strength of our Qingshan Pharmaceutical R&D team!"
"Besides, the current results of this leukemia drug are entirely the result of you and your first project team spending six or seven years, staying up many nights and doing countless experiments!
Who am I to point fingers at you? Intervene with you? ”
As he spoke, Zhang Yang's tone became more sincere and his expression became more solemn.
"So, Zhou Bo, just treat yourself as an ordinary drug developer, don't worry about the rest!"
Dr. Zhou was deeply moved by Zhang Yang's sincerity, and a look of shame appeared on his face.
Soon, he took a deep breath and said:
"Mr. Zhang, are you sure you really want to participate?"
"After all, you have to manage all the affairs of our entire Qingshan Pharmaceutical. Are you too busy?"
"I'm fine!"
Zhang Yang nodded firmly.
"Don't worry, whatever R&D tasks you arrange for other colleagues, you also arrange R&D tasks for me! Even if I am busy with something, I will definitely make up for the day's experimental tasks after get off work!"
"Don't forget... In addition to being the boss of Qingshan Pharmaceutical, I am also a drug developer. I also want to contribute my share to this potentially curable leukemia drug!"
"So, I want to fight side by side with everyone to fight side by side for mankind to conquer terminal leukemia!"
Dr. Zhou was completely stunned. At this moment, he seemed to see some kind of human brilliance in Zhang Yang!
Fight side by side and fight side by side for mankind to conquer terminal leukemia!
In an instant, the original intention that had been hidden in his heart for decades, and when he entered the biopharmaceutical industry in ignorance suddenly came to mind!
When I entered the pharmaceutical industry, wasn't it because I was passionate and wanted to conquer various diseases in humans? !
Don’t you just want to develop a variety of drugs to cure diseases and relieve patients from pain?
Over the years, as I have grown older, gained higher status in the industry, and experienced too much, I have completely lost my original intention!
But at this moment, his blood surged, and his original intention was back!
After a while, Dr. Zhou looked at Zhang Yang sincerely and said excitedly: "Mr. Zhang, I admire you!"
"I sincerely welcome to join our team and let us fight together to defeat the terminally ill leukemia in humans!"
"Okay, let's fight to defeat leukemia!"
……
On the other side,
Department of Hematology, Third People's Hospital, Chenggong.
Xia Xue, who was in bed 39, had her head shaved and was wearing a blue and white checkered hospital gown. She was weak and propped up beside the bed and kept vomiting.
Lao Xia stood aside holding a trash can while gently patting her daughter on the back, with pain and helplessness in her eyes.
He knew that this was a side effect of chemotherapy.
Actually,
Five years ago, after his daughter Xia Xue was diagnosed with "memory-associated leukemia" for the first time, he accompanied her through chemotherapy and experienced these things.
I remember that the first time, he rushed to consult a doctor anxiously because he couldn't stop vomiting, but the doctor was not surprised. Until now... he has become accustomed to it.
Even,
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Five years ago, when he first heard that his daughter was going to undergo chemotherapy, he thought that chemotherapy would be administered on a certain machine.
Later I learned that chemotherapy is not much different from infusion, that is, chemotherapy drugs are injected into the patient's body through infusion.
If there is any difference, it is that chemotherapy has a more precise treatment cycle than ordinary infusion therapy. For example, his daughter’s chemotherapy regimen is the standard regimen for the treatment of “acute myeloid leukemia”:
"3+7" treatment plan for a total of ten days.
After using "daunorubicin" for three consecutive days, use "cytarabine" for seven consecutive days.
Of course, this is just a course of treatment.
They need to perform this kind of treatment at least four times, and they have to decide whether to increase the number of chemotherapy treatments based on the last one.
Fortunately, each chemotherapy cycle needs to be separated by 30 days,
In other words, they still have at least 4 months to prepare for the bone marrow transplant.
Thinking of this, Lao Xia gradually recovered his thoughts. Seeing that Xia Xue stopped vomiting, he hurriedly put down the trash can in his hand, and then carefully handed the water glass on the bedside table to his mouth.
"Xiaoxue, drink some water and rinse it out."
"Yeah."
Xia Xue weakly took a sip with a straw, and Lao Xia finally breathed a sigh of relief.
After a while, he put the water glass back on the bedside table, then opened the drawer and took out two different potions.
"Xiaoxue, it's time to take medicine."
"Okay."
As he said that, Xia Xue's eyes fell on the two potions in his hand, and she suddenly became dazed.
The biggest difference between chemotherapy and ordinary infusion therapy is that although chemotherapy drugs can destroy cancer cells, they can also cause huge damage to normal cells and normal organs of the human body.
For example, platelets are significantly reduced.
For example, liver and kidney indicators are significantly abnormal.
Therefore, during chemotherapy, in addition to injecting chemotherapy drugs, doctors will also inject nutritional drugs, stomach-protecting drugs, and kidney-protecting drugs into the body through liquids.
The white pill in front of me is "Tsingshan Avatrombopag" from Tsingshan Pharmaceuticals.
Xia Xue suddenly sighed softly.
In fact, she had already taken Tsingshan Pharmaceutical's "Tsingshan Avatrombopag Tablets" when she underwent her first chemotherapy five years ago.
This first-line drug, which was originally most commonly used in patients with aplastic anemia, is rarely used in patients with aplastic anemia with the emergence of "ITG human myelopoietin". Instead, it has become a necessary drug for countless cancer patients.
Because every cancer patient needs to undergo chemotherapy, chemotherapy will inevitably cause a large decrease in platelets.
After thinking about it, she suddenly said:
"Dad, how much does a box of Qingshan Avatrombopag tablets cost?"
Lao Xia was stunned for a moment and shook his head:
"This medicine doesn't seem expensive, right? You ran a special outpatient clinic, and the reimbursement seems to be several dozen yuan?"
"Oh."
Xia Xue's eyes fell on another green capsule.
She had not used this drug during chemotherapy five years ago, but she knew the name of this drug during her first chemotherapy treatment after relapse last month.
"Activating agent that promotes liver cell regeneration".
The one that protects liver is also from Qingshan Pharmaceutical.
She specifically asked about the price of this medicine last month, and it was much more expensive than Qingshan Ava. After reimbursement, a box was as high as 2,500 yuan!
But fortunately, one chemotherapy cycle only requires one pill per day, ten pills in total. One box of pills can be used for three chemotherapy cycles!
"Hey, although Qingshan Pharmaceutical failed to develop a drug to treat 'leukemia', at least these two drugs also protected my body."
“Especially Qingshan Afa, it used to cost seven to eight thousand per box!”
Thinking silently in her mind, she immediately put the two potions into her mouth and swallowed them skillfully.
Lao Xia on the side showed a rare smile when he saw this. While handing over the water glass, he comforted:
"Xiaoxue, Director Hu also said that the results of your two chemotherapy treatments are good. After four courses of treatment, we will perform stem cell transplantation. You must be stronger!"
"Yeah."
Xia Xue nodded and lay on the bed.
Not long after, she suddenly said:
"Dad..."
But as soon as she said the words, she suddenly stopped and turned her head slightly.
Lao Xia was stunned for a moment, and then felt Xia Xue's sensitivity.
Knowing his daughter Mo Ruofu, he instantly guessed what Xia Xue wanted to ask.
"Xiaoxue, don't worry about the bone marrow stem cell matching. Your mother called me yesterday. She went to your uncle's and aunt's houses today to explain the situation to them. Your uncle and the others can't ignore you."
"Don't worry."
As soon as he finished speaking, the mobile phone in Lao Xia's bag suddenly rang.
At first glance, it was Xia Xue's mother calling.
Could it be that they are willing to match the donation?
"This is a call from your mother. I'll go out and pick it up."
Lao Xia ignored her daughter and hurriedly walked out of the ward.
(End of chapter)