Chapter 308 WPG0307: How to make Wugengtian become a world-class pharmaceutical giant? 134K
After An Wuyang secretly decided to use the character rating subsystem, he did not think about Gu Mingyue's intention. He responded to Gu Mingyue's cousin Zhan Chunfeng, "You're welcome, we help each other!"
An Wuyang added a reminder, "We have very high quality control requirements for white peony on the fifth watch day, and we hope that Brother Chunfeng will pay more attention to it."
Zhan Chunfeng said with assurance, "Brother Wu Yao, please rest assured!"
This guy is obviously older than An Wuyang, but he calls him 'brother' quite smoothly.
While An Wuyang and Zhan Chunfeng were chatting, Gu Mingyue walked directly to Yang Yuxin, moved her chair to get closer to Yang Yuxin, and then sat next to Yang Yuxin.
Yang Yuxin's expression was a bit embarrassed.
Zhan Chunfeng's expression was even more embarrassing. He couldn't help shouting in reminder, "Cousin!"
However, Gu Mingyue didn't pay attention to Zhan Chunfeng's intention. She took the initiative to ask Yang Yuxin, "Yuxin, what method did you use to get Mr. An to give your Ping An Xingtian Group an additional quota of 1 million Shuxin Pills?"
After Gu Mingyue's question came out, everyone looked at Yang Yuxin.
This Yang Yuxin actually asked An Wuyang to increase the quota of 1 million Shuxin Pills for Ping An Xingtian Group?
Lin Qianli looked at Yang Yuxin in surprise, because Lin Qianli's girlfriend Yang Yuting was Yang Yuxin's cousin, and he knew Yang Yuxin's character.
An Wuyang came to the rescue instead of Yang Yuxin, "This time we replenished Ping An Xingtian Group's share of 1 million bottles of Shuxin Pills on the fifth day of the night. That is to commend Ping An Xingtian Group's past performance. Don't let your imagination run wild."
Chen Hongzhi teased, "Oh~~~I understand!"
Xu Le also started cheering, ‘Haha, I understand too! ’
Lin Qianli also agreed, "Anyway, Brother Wuyou said it, so I believe it!"
Yang Yuxin's face turned red, and she responded to Gu Mingyue, "Our Ping An Xingtian has sold all 1 million copies of Shuxin Pills in North China, but the other four dealers on Wugengtian are playing tricks and are preparing to sell their products overseas. .”
"In view of this reason, Mr. An specially replenished the quota of 1 million bottles of Shuxin Pills for our Ping An Xingtian Group." Yang Yuxin added.
Gu Mingyue looked at An Wuyang, "Is this the performance of Ping An Xingtian Group worthy of commendation?"
An Wuyang didn't want to talk about this topic anymore. He skipped Gu Mingyue's inquiry and looked at Chen Hongzhi and asked, "Brother Hongzhi, how is the recent situation of the Carbon Change team?"
Chen Hongzhi complained, "No, buddy, haven't you figured it out yet?"
"Aren't you a pharmaceutical R&D company on Wugengtian? Why do you want to invest in the chip field?" Chen Hongzhi asked doubtfully.
Gu Mingyue heard the topic of the Carbon Change team, and she didn't ask about the previous topic for a while.
"Is everyone curious about this?" An Wuyang asked.
Lin Qianli responded affirmatively, "I am indeed curious!"
"Logically speaking, your Wugengtian Pharmaceutical Group should focus on the pharmaceutical field. Even if you want to invest, you should invest in Professor Wei Zhenghong's team to continue to develop the lupus erythematosus project, rather than focusing on the carbon change team." Lin Qianli explained.
An Wuyang responded affirmatively, "We are also very interested in Professor Wei Zhenghong's team and projects during the fifth watch."
"As for the Carbon Change team." An Wuyang was silent for a moment.
Xu Le spoke first, "Could it be that Brother Wu Yang wants to break the restrictions in the chip field?"
When Gu Mingyue listened to Xu Le's words, she couldn't help but raise her eyebrows.
An Wuyang shook his head, "That's not the reason."
"Although many netizens like to fantasize about this statement on the Internet, such fantasies are too unrealistic." An Wuyang sighed.
"You may wonder why we invested in the carbon change team on the fifth day of the week. It's actually because you don't understand the field of medical research and development." An Wuyang added.
“In 1994, an [International Protein Structure Prediction Competition] was held internationally. This competition is held every two years. In the previous 12 competitions, all [human contestants] participated, so the performance gap between them is not big. ." An Wuyang explained.
"Three years ago, Google's artificial intelligence system AlphaFold participated in the 13th [International Protein Structure Prediction Competition] for the first time. Can you guess the result?" An Wuyang asked everyone to guess.
Before anyone spoke, An Wuyang continued, "In the past, the general public's attention to the Alpha series of artificial intelligence systems tended to focus on AlphaGo, thinking that the so-called artificial intelligence system could only play Go, but in fact, artificial intelligence systems are very important in the medical field. Already a sudden rise.”
Chen Hongzhi asked curiously, "Did AlphaFold defeat humans?"
"Of course!" An Wuyang replied affirmatively, "This artificial intelligence system directly defeated all human contestants for the first time and won first place."
An Wuyang continued to add, "Last year, in 2020, the AlphaFold artificial intelligence system was updated to the second generation, AlphaFold2, and once again participated in the International Protein Structure Prediction Competition."
"The results this time are even more exaggerated!" An Wuyang sighed, "In this competition, the scoring range of human players ranged from 40 to 60 points, but Google's AlphaFold2 artificial intelligence system directly scored 90 points points, thus taking the lead and winning the championship.”
"Perhaps you don't know much about [proteins]. The [proteins] in this [International Protein Structure Prediction Competition] are not [proteins] in the popular sense." An Wuyang reminded in particular.
"The [protein] in this competition is the basic component of all living things on earth. It is a very basic and very small unit of life." An Wuyang explained. "Just like in physics, physical substances are composed of different atoms in different arrangements to form various molecules, and then to form substances, different proteins are combined to form different cells, and then to form different life forms." An Wuyang gave an example. illustrate.
Everyone listened to An Wuyang's explanation.
"Take us humans as an example. Each human body has approximately 40 trillion cells, which together form a human being. This shows how subtle a cell is, right?" An Wuyang took humans as an example.
"However, such a tiny cell contains tens of billions of [proteins]. This [protein] is the protein mentioned in the [International Protein Structure Prediction Competition]." An Wuyang explained the specific meaning of the protein in the competition.
"Can you imagine how small a protein is?" An Wuyang asked.
Everyone fell into silence, maybe they were doing mental calculations?
A human being is composed of approximately 40 trillion cells, and a cell is composed of tens of billions of proteins. Which human being is composed of more than 40 trillion proteins?
‘Trillions of trillions’?
What a niche counting unit!
"There are hundreds of thousands of different types of proteins among the tens of billions of proteins in a cell. If you add this order of magnitude up again, what is the concept?" An Wuyang asked teasingly.
“This [International Protein Structure Prediction Competition] takes out several or dozens of proteins at a time, and allows contestants to predict the three-dimensional structure information of the corresponding proteins, and then compares the predicted information with the actual information to judge who is more powerful. Predict the corresponding three-dimensional protein structure information accurately and quickly." An Wuyang also explained the rules of the competition.
"We just said that proteins are equivalent to molecules. If you refine it down from the protein level, you can refine it to the amino acid level. Currently, there are about 500 known types of amino acids, but there are only three types of amino acids that make up life. Twenty fixed types." An Wuyang continued to explain.
"I won't tell you the specific types. You won't understand even if I do, even though I can't remember them myself." An Wuyang chuckled.
Check out the 16-9 book bar and see the correct version!
He only knew some basic information because of the family business, but he didn't actually remember more specific things when it came to in-depth detailed information.
"A protein can be composed of a few amino acids or dozens, or even hundreds or thousands of amino acids, and proteins folded out of different amino acid chains will have different three-dimensional structures." An Wuyang explained.
(↑Protein three-dimensional structure concept diagram)
"Different three-dimensional structures determine different functions of proteins. Even small changes in the structure of the amino acid chain can make the final function of the protein significantly different." An Wuyang continued.
"For example, the famous Alzheimer's disease is caused by problems with the protein folding structure, which leads to the corresponding dementia." An Wuyang gave an easy-to-understand example.
"There is an important knowledge point about proteins, that is, the protein folded out by a string of amino acid chains with the same sequence in the same environment will always be the same. This involves knowledge of physics, because they all need to achieve a relatively stable structure. The lowest energy state." An Wuyang explained.
At this point, An Wuyang asked teasingly, "Don't you laymen understand it anymore?"
Chen Hongzhi nodded, "I really don't understand!"
"It doesn't matter, you will soon know what I am talking about and why I want to invest in the Carbon Change team again!" An Wuyang responded.
"The [International Protein Structure Prediction Competition] was established based on this important knowledge point. After all, the folding conditions of amino acid chains are the same under the same conditions, which means that the corresponding proteins can be predicted." An Wuyang explained.
"So the rules of the competition are to tell the contestants a fixed sequence of amino acids, and through the known order of arrangement and combination, analyze and predict the three-dimensional structural information after they fold into proteins." An Wuyang introduced the rules of the competition.
"Through my explanation, everyone understood the meaning of protein, how tiny it is on a physical scale, and how exaggerated its quantity is. Now we bring the issue back to the artificial intelligence system AlphaFold2." An Wuyang began to wrap up. topic.
“Google is using the AlphaFold2 artificial intelligence system to conquer the entire protein information database. This so-called protein information database contains approximately 280 million pieces of protein sequence information. Currently, this artificial intelligence system has conquered the prediction of more than 200 million protein three-dimensional structure information. ." An Wuyang illustrates the extraordinary performance of the artificial intelligence system AlphaFold2.
"As for why only more than 200 million proteins were predicted, the answer is simple. Because the remaining sequences are either too short or redundant and have little research value, so they were screened out by AlphaFold2." An Wuyang explained. .
"What is this concept? Let me explain it in a way that is easier for everyone to understand." An Wuyang tried to explain the importance of artificial intelligence systems in the medical field in a simpler way.
"In this [International Protein Structure Prediction Competition], its question bank contains more than 200 million questions. Each competition only needs to take out a few questions or dozens of questions for the contestants to solve. If it is a traditional manual Analysis methods, such as problem-solving methods such as X-ray crystal diffraction, nuclear magnetic resonance, cryo-electron microscopy, etc." An Wuyang paused for a moment.
"Using these methods to analyze the three-dimensional structural information of complex proteins, even if only one complex protein is analyzed, will take several months." An Wuyang sighed.
"It is precisely because of this that each competition only needs to analyze the three-dimensional structure information of a few complex proteins or dozens of simple proteins, so as to avoid that the question makers have no time to study the correct answers." An Wuyang joked.
"However, Google's AlphaFold2 artificial intelligence system has broken the traditional limitations. For it, this competition has become its toy, because it has broken through all the question banks of this competition. For it, this competition It makes no sense." An Wuyang described the power of the AlphaFold2 artificial intelligence system.
"If there are no accidents, Google's AlphaFold2 artificial intelligence system is very likely to win a Nobel-level award, possibly in chemistry or medicine." An Wuyang added.
"In addition, there are billions or even tens of billions of protein types on the earth. If humans are allowed to slowly study them one by one, how long will it take to study them?" An Wuyang said about the relevant prospects.
"But if you use this AlphaFold2 artificial intelligence system, you can study proteins more easily and develop medical projects based on lower-level logic." An Wuyang explained the connection between proteins and the field of medicine.
"Our Wu Gengtian is relatively weak in these aspects, coupled with the related blockade in the chip field. If we Wu Gengtian wants to become a world-class pharmaceutical company, we can only find our own way." An Wuyang sighed.
"We can't be allowed to buy chips with backward performance and then use overseas system tools to conduct our own drug research and development, right?" An Wuyang complained.
Isn’t that half the result with half the effort?
More importantly, who knows if these things have backdoors?
Maybe some people think that if these devices are not connected to the network, then everything will be fine?
Is it possible that these devices have a certain information threshold preset inside them? When a certain information threshold is reached, the equipment will malfunction, so that relevant information can be extracted during door-to-door maintenance?
Don't ask how An Wuyang knew about this kind of thing.
It’s easy to make mistakes if you talk too much!
"Brother Hongzhi, do you understand now why I want to invest in the Carbon Change team?" An Wuyang looked at Chen Hongzhi.
An Wuyang's investment in the Carbon Change team is not to do traditional chip research and development work, but to promote Wugentian Pharmaceutical Group to become a world-class pharmaceutical giant!
(End of chapter)