Chapter 110 The devil will never let you down! (Please subscribe)
Xiao Xiba’s attitude of never giving up made it clear that he was asking for a slap in the face, so Zhang Wei decided to meet his request.
So Zhang Wei asked: "Is the solvent you used methanol or acetonitrile?"
"It's methanol!" the female assistant researcher replied.
"What about the concentration? 50% or 55%?" Zhang Wei continued to ask.
"55%." The female assistant researcher's tone has become serious.
Being able to ask whether the solvent is methanol or acetonitrile, and also asking whether the concentration is 50% or 55%, this is definitely knowledge that only an expert can master.
“It’s not that 55% methanol solvent cannot be used, but in your experiment, using 55% methanol will not achieve the best experimental results. If I read it correctly, your experiment is Do you need to maintain the activity of the enzyme?" Zhang Wei continued.
"How do you know? Do you conduct this experiment?"
The female assistant researcher's rhetorical question also confirmed that what Zhang Wei said was correct.
Zhang Wei did not answer, but said; "In DESI experiments, the best solvent or solvent combination depends on the specific analyte and experimental conditions. Since you want to maintain the activity of the enzyme, you should choose non-volatile solvents with high salt content." The solution serves as a solvent!”
“Are you talking about sodium chloride?” the female assistant researcher asked with a frown.
Zhang Wei shook his head: "Although sodium chloride is better than methanol, it is not the best choice. I think the best solvent should be sodium sulfate."
The female assistant researcher immediately fell silent. She was thinking about whether what Zhang Wei said was right.
Seeing that the situation was not good, Huang Junji immediately spoke up to disrupt the situation: "You said to use sodium sulfate, then you have to use sodium sulfate! You must be right!
You are just an exchange student from China, and you are not an industry authority! There are so many outstanding researchers at Lawrence Berkeley National Laboratory, are they not as good as you? ”
“He is right! "A voice suddenly sounded, and everyone looked in the direction of the voice. A Chinese man in his fifties, wearing glasses and looking a little thin, was walking towards this way.
Seeing this man When they came, several researchers who were sitting in front of the computer immediately stood up, looking very respectful.
"Director, why are you here!" "Someone immediately came up to him.
The Chinese man waved his hand and then looked at Zhang Wei: "This classmate is right. If you want to retain the best activity of the enzyme, a non-volatile solution with high salt content should be used. , is indeed a better solvent choice. Using sodium sulfate is also more effective than sodium chloride! ”
"Chinese people are against Chinese people!" Huang Junji muttered dissatisfiedly.
The researcher next to him said: "Let me introduce to you, this is Steven Chu, the director of Lawrence Berkeley Laboratory!"
"It turns out to be him!" Zhang Wei showed a sudden realization. expression.
"Do you know him? Are you an acquaintance?" Ye Haotian asked in a low voice.
Ye Haotian felt that the person who suddenly came out and spoke for the big devil was probably an acquaintance.
"Don't you want to meet the Nobel Prize winner? He is it! Steven Chu, the 1997 Nobel Prize winner in Physics!" Zhang Wei said.
"Chinese Nobel Prize winner? I seem to have some impression." Ye Haotian said.
"The fifth Chinese scientist to win the Nobel Prize after Yang Zhenning, Li Zhengdao, Ting Zhaozhong, and Li Yuanzhe." Zhang Wei went on to explain.
The memory of an ordinary person like Zhang Wei is not enough to remember every Nobel Prize winner. But this Steven Chu is indeed a bit special. In addition to being Chinese, he will also become the Secretary of Energy of the United States in the future, so he looks familiar to Zhang Wei.
Since 2004, Steven Chu has served as the director of Lawrence Berkeley Laboratory and is also the first Chinese-American head of the laboratory.
When the big leader arrived, all the researchers around him stopped what they were doing and stood up respectfully. The exchange students who came to visit also showed solemn expressions.
The female assistant researcher’s frown instantly relaxed. Since Zhu Diwen said that Zhang Wei’s solvent solution was right, then it must be right.
Huang Junji looked embarrassed again.
He just finished saying that you are not an authority in the industry! An industry authority really came right away.
And he is also a top authority with the right to speak. Not only is he a Nobel Prize winner, he is also the head of the entire Lawrence Berkeley National Laboratory!
The slap in the face was a little too fast, and Huang Junji himself didn't even react.
Zhu Diwen looked at Zhang Wei and asked: "This classmate, which university are you an exchange student at?"
"Hello, director, I am from Tsingta University in China. "My name is Zhang Wei." Zhang Wei replied.
"Tsinghua University! My father also graduated from Tsinghua University." Zhu Diwen smiled, probably because he felt that he had some connection with Zhang Wei.
Zhu Diwen's father graduated from the Chemistry Department of Tsinghua University in 1940, and then studied in the United States and received a PhD in chemistry from MIT. Zhu Diwen's grandfather, Li Shutian, served as the Minister of Education during the Republic of China.
Those who could stay in the United States in those days were either rich or noble.
Zhu Diwen then asked: "Classmate Zhang, how did you come up with the idea of using a non-volatile solution with high salt content as a solvent?"
"Knowing the principle of EDSI, it should not be difficult to think of it. Come on!" Zhang Wei said with a smile.
"This is not easy. All the researchers here know the principles of EDSI, but no one has ever thought of using sodium sulfate as a solvent."
Zhu Steven then asked: "Apart from solvents, do you What else came to mind? "
"Many, the existing EDSI technology is not mature yet, and there are many areas that can be improved." Zhang Wei said with confidence.
Now that the big boss Zhu Steven has appeared, Zhang Wei feels that it is time to show off, and there is no need to hide it.
Americans have always been accustomed to speaking from the standpoint of strength and status. Fist is the language that Americans can understand best. And showing your fists in front of a big boss is definitely more effective than showing your fists in front of ordinary researchers.
As expected, when Zhang Wei said that there are still many areas for improvement in desorption electrospray ionization technology, Zhu Steven immediately asked: "What about?"
"Optimization of spray solvent and conditions, such as the composition of spray solvent, spray voltage, spray flow rate and other parameters, can improve the ionization efficiency and desorption capacity.
The ion transmission efficiency can be improved, which will affect the ion transmission pipeline and The interface has been improved, using more efficient ion transmission pipeline materials and designs, reducing ion loss and diffusion, improving signal stability and sensitivity.
The treatment of the sample surface can be more refined, using specific coatings or Modifiers can change the properties of the sample surface, making it easier to interact with the spray solvent and ionize..."
Zhang Wei listed several areas that could be improved.
After 2010, these are the basic optimization plans for desorption electrospray ionization technology. Zhang Wei, an ordinary inspector, can propose them casually after becoming familiar with this technology.
However, in 2004, when desorption electrospray ionization technology first appeared, what Zhang Wei said was a revolutionary breakthrough in this technology!
When he first listened, Steven Chu still kept a smile on his face and acted as calm and calm as a Nobel Prize winner.
But as he listened, Steven Chu's smile froze, replaced by a solemn expression of serious thought.
Finally, when Zhang Wei finished speaking, Steven Chu could no longer maintain the stability of a Nobel Prize winner, and a shocked color appeared on his face!
Zhang Wei's speaking speed is not fast, so Zhu Diwen can listen and think and analyze whether what Zhang Wei said is feasible.
As a Nobel Prize-level scholar, Steven Chu responded quickly. His thinking and analysis could keep up with Zhang Wei's pace. It was also true that Chu Stevens immediately realized how important what Zhang Wei said was. important!
This is not improving technology, this is a technological revolution!
If we optimize according to what Zhang Wei said, the effect of desorption electrospray ionization technology will rise several levels, and the resulting breakthroughs in scientific research results will also jump by leaps and bounds. develop.
Not far away, Ye Haotian looked at the change in Zhu Xiwen's expression, with a proud smile on his face, and he was even happier than he was pretending to be.
“As expected of my great devil, he has never let me down!”
Half a minute later, Steven Chu gradually came back to his senses, and he said: "Classmate Zhang, what you said is enough to write a paper on improving EDSI technology."
"It's a pity that I don't have time. And I don’t have experimental equipment to prove my point!” Zhang Wei shrugged.
"Is Mr. Zhang interested in cooperating with our researchers to complete this paper?" Zhu Diwen asked immediately.
With Zhang Wei's current situation, it is really impossible to complete this paper independently.
Technical improvements in desorption electrospray ionization still require experiments to verify the results. Without verification of results, there are only dry plans. That is called conjecture, not a paper.
This new technology is currently only available at top scientific research institutions in the United States, and Zhang Wei can only cooperate with researchers here.
Zhang Wei thought for a moment and nodded: "The researchers at Lawrence Berkeley National Laboratory are all excellent, and I would love to be able to cooperate with the researchers here."
"In that case, Which of you is willing to cooperate with Zhang to complete this paper?" Zhu Diwen looked at the researchers around him.
“I can!” Someone immediately raised his hand, it was the female assistant researcher named Zhou.
"Hey! This girl is the first one to jump out!" Zhang Wei thought to himself.
The female assistant researcher said; "Classmate Zhang is from Tsinghua University in China. I also completed my bachelor's degree in China. I can communicate with Classmate Zhang in Chinese, which will make communication easier."
"Look Now that you can produce scientific research results, do you think of China?" Zhang Wei was filled with disdain.
Zhu Diwen looked at several other researchers. They looked at each other without any expression.
It’s not that these researchers are not interested in this paper, but they think that since Zhang Wei and the female assistant researcher are Chinese, there is no need for them to get involved.
"Classmate Zhang, what do you think about Linda Zhou cooperating with you to complete this paper?" Zhu Steven asked again.
The female assistant researcher immediately looked at Zhang Wei expectantly.
Zhang Wei didn't like this Runren in his heart, but the other researchers didn't say anything, so Zhang Wei could only choose her
So Zhang Wei had no choice but to nod and agree: "I still There are many tasks for exchange students to complete, and I usually don’t have that much time. I can only provide ideas and directions for improving technology, specific experimental steps, and writing papers. Only you can do it.”
“No. Question, you just need to provide ideas, I will do the experiments and write the paper!" Researcher Runren nodded immediately.
"What about the signature of the paper?" Zhang Wei asked again.
"Is that okay if we sign together?" Researcher Runren said immediately.
"Then I'll have no problem." Zhang Wei nodded.
Zhu Diwen continued: "When the paper is finished, show it to me for a look. I am also interested in the improvement of EDSI technology!"
……
In the corner, Huang Junji looked at Zhang Wei with a gloomy face, and then silently hid the recording pen.
"You're not the only one who can write it! Whoever writes the essay first gets it!"
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(End of this chapter)