Chapter 204 Eat a Fat Man
Professor Shi looked at the paper handed over by Zhang Wei with a look of surprise on his face.
The paper has been written, which proves that the scientific research project has been completed. But it only took a few days, how could the project be completed?
Looking at the title of the paper, the phrase "induced pluripotent stem cells" caught Professor Shi's eyes. The emergence of the phrase induced pluripotent stem cells also means that the project has achieved results.
Professor Shi quickly opened the paper. He skipped the beginning and middle and went straight to the final conclusion.
"IPS cells differentiated nerves and muscle tissue? It really succeeded!"
While surprised, Professor Shi also took a breath of air. This is used to replace embryonic stem cells, so short. Time allowed Zhang Wei to do it.
"Brother, how about I briefly report the experimental steps of the project!" Zhang Wei gave a general introduction to the experimental process.
"Zhang Wei, are all your projects so smooth? Just do it step by step, and the results will be achieved? Are there no obstacles in the way?" Professor Shi asked with a curious look on his face. .
"What? You still expect me to encounter obstacles in my experiment!" Zhang Wei asked with a smile.
"That's not what I mean. What I mean is that when we usually do experiments, we always have to go through some processes of failure, and then we summarize the experience through failures, eliminate wrong options, and finally obtain the experimental results!" Professor Shi explained.
“So you are all conducting experiments like this!” Zhang Wei showed an expression of sudden realization.
“You’re not?”
“I’m not. I’ve never failed in experiments!”
Looking at Zhang Wei’s awesome and coaxing expression, Professor Shi was immediately relieved gas.
He is a genius scholar who has produced Nobel Prize-level results at the age of twenty. You, an ordinary scientist, can't compete with a genius!
"Okay, let me read this paper carefully and give you an answer." Professor Shi paused and then asked: "What about what you just said, asking for leave to return to China to take the college entrance examination? What's going on? "
"Didn't I drop out of Tsinghua University? Do I have to find a way to go back to college? I can't take the college entrance examination!" Zhang Wei replied with a smile.
"Do you still want to take the formal route? Let alone Tsinghua University. Even if you want to come to Princeton, you don't need to start as an assistant professor. I guess the school committee will give you at least one assistant professor."
< br>"The national conditions are different. Americans can get into good universities with letters of recommendation. It is not easy for domestic college students to pass the Qingbei exam. I can't be special!" Zhang Wei continued to talk nonsense.
"I really don't understand the thinking of you young people." Professor Shi shook his head helplessly, and then said:
"Also, what happened to that Sam? I told you before, this guy's I have some bad luck. I have already failed three projects in a row. If you ask him to be responsible for the subsequent experiments, are you not afraid that the project will be ruined by him again? "
"How about you arrange an obedient assistant professor for me? ?”
“Assistant professors basically have their own projects, or are working in other project groups, so there is no spare time for you.”
“Except for Sam, I really can’t. There is no one available. If you are unlucky, you can only use him. After all, he is an assistant professor, and his academic ability is very good. I would not worry if he was replaced by someone with average academic ability. And I will take him with me. He has worshiped God.”
"Worship God?" Professor Shi was stunned again, wondering what kind of trick this was!
"Every walk of life has a patron saint. For example, those who raise silkworms worship Leizu, those who do business worship Zhao Gongming, those who make paper worship Cai Lun, those who make pens worship Mengtian, those who make wine worship Dukang, and those who make wine worship Zao Zao Wang, the fishermen worship Mazu, the craftsmen worship Lu Ban, the tea fryers worship Lu Yu, the actors worship Li Longji, the cross talkers worship Dongfang Shuo, and the duet singers worship senior brother..."
"Wait a moment, take care of you. For this statement, should we worship Darwin, Newton, or Einstein? If we are young, should we worship Archimedes and Aristotle?”
“I asked Sam to worship him. Mr. Guan."
" Mr. Guan? Isn't he still in charge of scientific research?
"The main reason is that you can't find statues of other gods in the second-hand markets in the United States. Besides, Guan Erye's righteousness and Bo Yuntian are all the fault of others, so why should he help his brother!"
"Support my brother? Isn't this still a favor?" Professor Shi muttered in a low voice, and then continued to ask: "Also, I hear what you mean, the follow-up scientific research ideas are already in place? Do we need additional funds?< br>
If you want to add more funds, it’s not impossible. You have to wait until this paper is published and the results are obtained, and I can legitimately report to the school.”
“Before I come back! "There shouldn't be any need for additional funds. The money you gave me before has not been used up yet. It is enough for several experiments." Zhang Wei paused and then started to introduce the follow-up research on IPS cells.
At this stage, Mr. Zhang Wei found the genome, induced IPS cells, and proved the potential totipotency of IPS cells through immunodeficient mice.
However, if you want to perfectly replace embryonic stem cells, you need to verify other abilities of IPS cells, which requires a series of follow-up experiments.
In addition, there is still a lot that can be studied regarding the generation of IPS cells. For example, Zhang Wei is currently using viruses as gene vectors to inject into host cells. In the future, he can study not using viral vectors, and the safety of IPS cells will be greatly improved.
For another example, in the genome used by Zhang Wei, c-Myc is an oncogene. If other genes can be used to replace c-Myc, or nucleoside modification methods can be used to edit c-Myc, it will lose its carcinogenicity. , can also improve the safety of IPS cells.
This is only the development and research of IPS cells themselves. There are countless ways to use IPS cells for medical research to treat various diseases.
After listening to Zhang Wei’s introduction, Professor Shi fell into a brief silence. After a while, he slowly digested what Zhang Wei said, and then he said:
"Listen to what you said, you are planning to play a big game! If I finish studying what you said, your team will not be enough. I will have to add more people to you. But my population here is also a bit stretched, you It’s really going to be a problem for me!”
“Don’t worry, wait until I come back from China! The potential of IPS cells is huge, and the research on IPS cells cannot be completed in a day or two.
For scientific research, take it step by step and take your time! I’m not Nagasaki, so I can’t become fat in one sitting!” Zhang Wei said.
"Nagasaki? Eat fat?"
Professor Shi repeated it and understood what Zhang Wei was talking about.
What a metaphor! Just for eating fat in Nagasaki, I have to give you a thumbs up!
......
Zhang Wei moved the statue of Brother Guan to Sam's office.
"Sir Zhang, I have prepared food and drinks to welcome the gods!"
"Food? Drinks?" Zhang Wei's heart suddenly tightened, and he felt that this was not a person. A very reliable description.
Sure enough, when I arrived at Sam's office, I saw a table full of food and drinks on his desk.
“I prepared cheesecake, biscuits, cookies, blueberry tarts, apple pie, chocolate cake, as well as cheese sandwiches and appetizer salads.
As for fruits, I prepared apples, Oranges and grapes, this orange tastes great, I eat one every afternoon. As for nuts, there are pecans, almonds, macadamia nuts and black walnuts, as well as dried cranberries and dried cherries.
Drinks include coffee, black tea and green tea. I also prepared a bottle of 1999 red wine and authentic Kentucky corn whiskey! I originally wanted to buy a few bottles of beer..."
" I asked you to prepare a tribute, and you made me a table of afternoon tea?" Zhang Wei interrupted Sam's introduction.
Sam looked at his watch: "Yeah, it's afternoon now, it's time for afternoon tea!"
Zhang Wei was speechless for a moment: "Okay, since you have prepared so much, don't waste it. , take it to the lounge later, let's eat together!"
"Isn't it for the gods?"
"The gods can't eat so much, so I'll give it to you." Zhang Wei was helpless. He shook his head and then asked: "Where should I put the statue of Mr. Guan?"
"It's on the cabinet over there. I have specially cleaned a space." Sam pointed. a location.
Zhang Wei turned around and saw a garland placed on the cabinet!
"This..." Zhang Wei hesitated for a few seconds before placing the statue of Mr. Guan up.
Sam, with a pious look on his face, picked up the garland and put it directly around Mr. Guan’s neck.
“I guessed that this wreath was used like this!” Zhang Wei complained in his heart.
There is something in the West called Christmas wreaths. According to traditional Western customs, wreaths are hung on the doors at Christmas to ward off evil spirits, just like the Chinese door gods.
In many religious ceremonies, garlands are also used. For example, in churches, garlands are often seen as decorations.
At this moment, Sam has obviously moved Western religious rituals here.
However, what Zhang Wei didn't expect was that wearing a garland was only the first step. Sam didn't know where he came from, and took out a metal goblet, and placed it next to the statue of Guan Erye.
"What is this? Does it serve wine?" Zhang Wei asked subconsciously.
"This is the Holy Grail!" Sam replied with a serious face. "Holy Grail?" Zhang Wei suddenly stood on the spot.
You might as well put a copy of "Spring and Autumn" in front of Mr. Guan!
Sam showed a triumphant expression and said: "How is it? I am well prepared!"
......
Arrange things in the United States. After that, Zhang Wei flew back to China to prepare for the 2005 college entrance examination.
But before that, Zhang Wei went back to Tsingta University and reported to Principal Gu the situation in the United States.
"You mean, you have found a substitute for embryonic stem cells in such a short period of time?" Principal Gu looked surprised.
Although Principal Gu does not study biology, he still has basic biological knowledge. He knows very well what the replacement of embryonic stem cells means.
Zhang Wei continued: "I obtained this kind of cells through gene induction, so I named them induced pluripotent stem cells, or IPS cells for short."
"Can it completely replace embryonic stem cells?" Principal Gu asked.
"In terms of biological characteristics and protein expression, it can replace embryonic stem cells. As for other genetic modifications, it still needs to be verified, but I think there should be no problem."
"Oh, what a pity!" Gu The principal suddenly showed a regretful expression and continued: "Such good scientific research results should be done at Tsinghua University! Princeton University is cheaper!
In this case, the intellectual property rights of IPS cells are all in Princeton University. If we want to use IPS cells for scientific research, we might be blocked by the Americans.”
“Principal, don’t worry, there is not only one way to induce IPS cells!” Zhang Weiyi! He said with a calm face.
Principal Gu’s eyes suddenly lit up: “Have you thought of other methods?”
"In scientific research, there will never be only one way! Principal, don't worry, I will definitely leave a better way to the Chinese people for our own use, and of course it will not be in vain for the Americans."
"Seeing that you are so confident, I feel relieved." Principal Gu breathed a sigh of relief, and then asked: "By the way, before you left, you said you wanted Professor Shi to return to Tsinghua University. How was the discussion? ?”
“Professor Shi’s contract with Princeton University will not end until 2008, so he will not be able to come back until 2008.”
“That’s three years away. Quickly, with a snap of a finger." Principal Gu nodded. As long as Professor Shi can come back, Tsinghua University can afford to wait for three years.
Zhang Wei continued: "Principal, my thesis this time will be published as soon as June. This is the first bargaining chip we have bet on. You must make good use of this bargaining chip by then. Ah!”
"Don't worry, I have made arrangements with the Publicity Department. As soon as your paper is published, we will immediately put a big satellite in the media!"
"Then I have no problem. , I took the evening flight back to Qinhai, the college entrance examination is in a week, and I have to review quickly." Zhang Wei continued.
"College Entrance Examination? Why else are you taking the college entrance examination! Restoring your student status is not a matter of a word from me. Aren't you just looking for trouble for yourself in your idleness?" Principal Gu couldn't help but complain.
"Principal, am I not safeguarding the fairness of our college entrance examination? If I become famous later, people will check again and find that Zhang Wei is a well-connected person. He got into Tsinghua University through the principal's relationship. Then my personal If not, it will collapse!”
“You scored 750 in the college entrance examination and returned it twice. Who has ever seen a relationship with a score of 750? I want as many as you want!”
……
It’s the college entrance examination again. This is the third time Zhang Wei has taken the college entrance examination. But this time, Zhang Wei took the liberal arts exam.
When the arts and sciences were divided into subjects, the reason why Zhang Wei chose science was actually not because he was poor in liberal arts. On the contrary, his grades in liberal arts were quite good, especially geography and history. He worked hard and could score more than 90 points. Politics was a bit poor, just above the passing mark.
In terms of science, Zhang Wei's grades in the three subjects of physics, chemistry and biology are all good. His biology test score is over 90, and physics and chemistry is also above 80, with no shortcomings. It was also because of his good grades in biology that he chose the sinkhole major of bioengineering.
Such results, placed in other provinces, would definitely put him at the top of the list of academics. However, in the four provinces of Shanhe, where the college entrance examination is extremely difficult, he only scored 250 points in science and comprehensive studies, which is at the second level. It is difficult to stand up. A line.
Especially in the easternmost province, the undergraduate score line may not be the highest, but the number of candidates with high scores is the most.
This is extremely unfriendly to candidates with high scores. There are only a few good schools and good majors. If your score is higher, the competition will become more intense. If you are not careful, you will fall into the adjustment and choose a major that you do not want. .
On the contrary, candidates with lower grades can enter good majors even though their schools are worse.
How did Mr. Zhang Xuefeng choose between the Tiankeng major in a good school and the trump major in an ordinary school?
Out of the examination room, Zhang Wei went to the drugstore as usual and saw the aunt selling medicine again.
"Auntie, do you still remember me?"
"You are Kaiselu!" The aunt selling medicine recognized Zhang Wei at a glance.
"Auntie, you are still so incapable of speaking!" Zhang Wei sighed helplessly.
The aunt showed an excited expression, as if she had met her childhood best friend, and said in surprise: "Are you constipated again? Are you taking the college entrance examination again? Did you fail the entrance examination again last year?"
"Isn't that right, Auntie, I remember you said last year that if I take the exam again this year, you will send me a Kaisailu!"
"Give it! I'll give it to you! Even though you have passed the exam for the third year, aunt has to give it to you. Oh, this poor kid!"
The aunt muttered and took out a few bottles of Kaiserlu from the counter. , placed it in front of Zhang Wei, then hesitated, took another bottle of fish oil, and placed it on the counter.
"Auntie, this bottle is golden, or a small capsule. It doesn't seem to be Kaiserlu, right?"
"Young man, this bottle is fish oil. Auntie gave it to you too. This is fish oil. , can replenish your brain.”
“Do I look like I’m not very smart?”
"You've been taking the exam for three years! You still think you're smart!" The aunt's mouth was still rude. She continued: "Young man, if you don't listen to my advice, stop taking the exam and go to a technical school to learn a skill. , and you can support yourself.
Didn’t it say in the advertisement, which company has the best excavator technology? Where is the best place to learn to be a chef and pastry chef? Come to New Oriental Cooking School! >
"Auntie, you know the slogan so well, it seems you are a loyal viewer of Shandong Satellite TV."
As Zhang Wei said, he picked up the bottle of fish oil, looked at it, and then said: "This bottle of fish oil must be quite expensive. How much does it cost? How about I give you the money?"
"No need to pay, I said it would be given to you!" the aunt said grandly.
"When we open our doors for business, we can't let you do business at a loss! I took the kaiselu for nothing, and I have to pay for the fish oil."
"It's really not necessary. The fish oil is about to expire anyway. You can take it." Just eat it!”
“Is it about to expire?” Zhang Wei looked at the date and saw that it expired on June 18th, and there were still ten days left.
“This aunt is really good at giving favors.” Zhang Wei complained in his heart.
The aunt then said: "Actually, it's okay if it's a little expired. My Doudou eats expired fish oil."
"It's best not to eat things that have exceeded their shelf life, as they may be harmful to your health." Zhang Wei advised.
"It's okay, my Doudou has been eating expired fish oil. After eating it, not only did the hair stop falling, but the hair became shinier and brighter!"
"Shedding ?”
“Short-haired dogs usually lose hair twice a year for six months.”
Zhang Wei read it! Looking at the bottle of fish oil in my hand, I can see that my auntie is giving me a lot of dog food!
(End of this chapter)