Chapter 448 Animal Experiment Base
Hermes was hospitalized again, and his leg was saved. After three to four weeks of rehabilitation training, the external fixator can be removed, and the entire treatment is over.
Huang Jiacai received Yang Ping's entrustment and began to strategize. He already had a mature plan in mind.
First, a development company was established in the name of Yang Ping, which was actually an investment company focusing on investment in the pharmaceutical industry. Then he planned to use this investment company to control Ruixing and control more companies in the future.
In this company, Yang Ping occupies 90% of the shares and Xiao Su occupies 10% of the shares. The registered capital is 100 million. Huang Jiacai serves as CEO and legal representative and becomes Yang Ping's agent to help Yang Ping handle business matters. things.
Huang Jiacai is ambitious. He has a grand blueprint in his mind and then implements it step by step.
After Li Baosheng's surgery, Yang Ping did not need to do other surgeries for the time being. Song Zimo and Xu Zhiliang could complete them.
Xu Zhiliang cannot perform difficult surgeries now, but it is perfectly fine for an independent surgeon to perform general surgeries, and the surgery can be done beautifully.
In this way, Song Zimo's burden can be reduced a lot, and he can concentrate on performing difficult surgeries.
When he had free time, Yang Ping took the time to go to Guilin, Guangxi to inspect Xiehe's laboratory in Guilin.
For the Guilin laboratory, Yang Ping must have detailed information before he can design an animal experiment plan based on the laboratory conditions.
It is very convenient to go from Nandu to Guilin, Guangxi. The high-speed train only takes three hours, which is not much different from flying. Not to mention that you can enter the system space laboratory to read books and do experiments on the way.
After arriving in Guilin, Director He from the laboratory drove a Haval H9 with his driver to pick up Yang Ping.
The laboratory is located in Yanshan District, Guilin, where there is a breeding base for experimental monkeys. In order to facilitate the acquisition of experimental monkeys, Xiehe established the laboratory here.
"Professor Liang called me a few days ago and repeatedly told me that I must do a good job in reception."
Director He was very enthusiastic. When he received Yang Ping at the high-speed rail station, he shook hands and grabbed his backpack.
Lao He is the director of the laboratory. He used to work in the Animal Department of Guangxi Medical University. After the establishment of this laboratory, he applied to work here. This laboratory has no establishment, but the salary is much higher, and the work is interesting, which is very suitable for the laboratory. Ho's life expectations.
Before changing jobs, he also learned that this laboratory was established by Xiehe and had long-term plans, so he quit his original job and joined this laboratory.
Director He was a graduate of veterinary medicine. He loves animals and often studies them. He is an expert in experimental animals. He is familiar with the procurement, breeding and care of experimental animals, and is also familiar with the production of most current medical models.
In addition to Director He, there are more than a dozen permanent staff members in the laboratory. Together with rotating researchers, the laboratory usually has twenty or thirty people working there. On rotation, some come from Union Medical College, some from Hong Kong, and occasionally foreign scientific researchers come over. They usually stay no more than three months.
Along the way, Lao He introduced the situation of the laboratory. The Haval car did not know how long it had been walking before it stopped in the yard in front of several small buildings. There was a shed in the open-air parking lot. At least ten cars could be parked under the shed at the same time. The parking spaces are all standard parking spaces that have been drawn.
Lao He opened the door and Yang Ping got out of the car.
These small buildings are very beautifully built. They are all three stories. They have large yards and tall trees inside.
"The front building is the office and dormitory, the second building is the laboratory, and the last building is the breeding farm for experimental animals." Director He pointed into the distance.
Because the third building is farther away, it is located on an artificial island. A wide and deep trench has been dug around it. There is a bridge to cross, and an iron gate on the bridge is locked.
"I have prepared the baby monkey you want, as well as the scoliosis model. Now it is difficult to find a monkey. My classmate is in charge of the supply company. I told them, no matter what, we We need to ensure supply here, and they are not complaining. It is true that the supply of experimental monkeys is currently in short supply. Last time, an American company asked for 1,500 monkeys, but they refused and could not deliver the goods. "Director He told several large-scale experiments in Guangxi. Animal farms are all familiar.
Darwin said that humans evolved from monkeys, so monkeys are highly similar to humans in terms of genes, anatomy, immunity, physiology and metabolism. Therefore, monkeys are very suitable for medical and biological research experiments.
Especially in the pharmaceutical industry, the dependence on monkeys is even more obvious. Every drug has side effects. What are they? Carcinogenic, disease-causing, teratogenic, toxic, mutagenic, disabling, or even fatal? The best way to obtain data before applying it to humans is to obtain data from monkey experiments.
But not all monkeys are suitable for experiments. If you want to become an experimental monkey, you need to meet many conditions. Currently, the commonly used monkeys are rhesus monkeys and cynomolgus monkeys. These two monkeys are relatively close to humans in anatomy and physiology, and are currently the most popular monkeys. The most popular medical laboratory animal.
In Europe, it costs about 5,000 euros to raise a marmoset, and 20,000 euros for a relatively large macaque. However, in China, it only costs 8,000 yuan to raise a macaque that can be used for medical experiments.
The low cost of Chinese experimental monkeys determines that the price will be even lower, which is a huge temptation for foreign research institutions and pharmaceutical companies.
This kind of monkey, which costs 8,000 yuan, can be sold on the market for 12,000 yuan, with a gross profit of 50%.
With such huge profits, it is natural that some people are willing to make money from monkeys, and many "monkey breeding" bases have emerged in the country.
Guangxi, Hainan and other places are places with relatively concentrated monkey breeding bases. The raising of experimental monkeys also requires professional knowledge. As a monkey for scientific research, it not only needs to be physically healthy, but also mentally healthy, so their feeding conditions are very good.
"Now our laboratory is profitable, not only to meet our own experimental needs, but also to make money. In our free time, we rent out part of the laboratory to some biomedical research and development institutions to conduct drug properties and toxicity experiments. We charge on a daily basis, and a project charge can range from as little as Hundreds of thousands, even millions." Director He was obviously very happy.
"I will eat in the canteen at noon. There is a pig farm nearby. The boss is very familiar with me. I asked him to help me go to the slaughterhouse to buy some fresh meat and pig offal. I will be there later and cook as soon as the ingredients arrive."
According to Lao He's introduction, there are usually dozens of people eating in this laboratory, and the chef in the cafeteria is his wife.
Later, Lao He took Yang Ping to visit the laboratory. The equipment of this laboratory is not only complete, but also very advanced. There is an operating room with very sophisticated surgical anesthesia equipment, including extracorporeal circulation equipment, which means that it can simulate Heart surgery.
"When the demand for scoliosis models is urgent, they usually remove the erector spinae muscles to make scoliosis models. Professor Liang said that the model made by this method is not suitable for your experiment, so we selected For the experimental monkeys, all this category will be eliminated, and the monkeys prepared will have scoliosis caused by drug-induced teratology during the embryonic period, so that the soft tissue structure of the entire spine will be preserved. "Director He is very professional in this matter. People who are interested in their work and have a sense of professional honor will definitely be able to do a good job.
"Our suppliers have mature technology for making other disease models, such as Parkinson's disease models, diabetes models, obesity models, middle cerebral artery occlusion models, hypertension monkey models, and renal failure models. They all do a good job. They also There are experimental monkeys carrying specific genes to create special models such as AIDS. However, they are not very skilled in making scoliosis models. I have to participate in the guidance every time. My method of making scoliosis models is. "Professor Liang taught me." Lao He talked eloquently, and when he talked about experimental animals, he was very happy.
The business of experimental animals is also very professional. For example, the production of these models requires special breeding or drug injection to make monkeys suffer from the same diseases as humans, so that they can be used to study related drugs to treat diseases.
The specific method has a high technical content. Using drugs to create models is very particular about when to use drugs, what drugs to use, and how much drugs to use. It is also not easy to make a high-quality disease model.
After visiting the laboratory, Lao He took Yang Ping for a walk around the laboratory. This place could be used as a tourist attraction with a little development.
The laboratory probably invested a lot of money at that time. The animal island alone was built artificially, and the surrounding isolation river and animal resting area were all very well done.
The animal resting area has swings, slides, seesaws, wooden houses, etc. for these monkeys to play.
Around lunch time, Lao He received a call. Fresh ingredients had arrived. He asked the owner of the pig farm to get them, so he asked the driver to drive to pick them up. He told the driver not to delay, put the ingredients in the cockpit, turn on the air conditioner, and get the ingredients. Hand it over to the kitchen immediately when you come back. It doesn't matter the other ingredients. The offal must be fresh to make it delicious.
The driver drove the Haval out again. In fact, the transportation was very convenient. The roads were all made of cement. Compared with the cement roads in rural areas, they were much wider and still had two lanes.
Yang Ping was very reassured by the conditions of this kind of laboratory. If he hadn't come here in person, he wouldn't know the details. After inquiring about it like this, he had a clear idea. Many animal experiments could be done by them in the future.
In terms of technology, there is no need to worry, Lao He and these staff are very professional.
Those who are specifically engaged in research work are graduate students from Peking University, so there is no problem.
Several young people came back in a pickup truck. Lao He said: "These are Ph.D.s from Concorde. They know how to play. After work, they often go fishing. I heard you were coming today, so I asked them to catch a few fish." , I don’t know what the harvest will be like.”
The young man parked the car. There was a large bucket in the bed of the pickup truck. Two people climbed up and lifted it down.
"Let me see, it's good."
Lao He took Yang Ping over. There were several big fish in the bucket, causing water to splash everywhere.
"Send it to the kitchen." Lao He ordered.
"This is Dr. Yang!" Lao He thought of introducing him.
Several young people immediately greeted him respectfully. They may be familiar with Yang Ping's situation and were recommended by Professor Liang personally, so they seemed a little more restrained.
"Have you bought all the drinks? Beer, no less beer."
Old He yelled, and it was obvious that he usually got along well with these young people.
"This car is so dirty, go wash it." Lao He felt sorry for the car.
The young man drove the car aside, picked up the faucet, and started washing the car.
"Look, if you need anything else for the experiment then, just tell me."
Lao He took Yang Ping to read it and asked Yang Ping.
Each experimental project has its own specific requirements, and Lao He needs to prepare in advance.
"If monkeys are used for spinal surgery, is there a spinal surgery positioning frame to fix the monkey?"
Yang Ping just took inventory, and this was the only thing missing.
"Yes! There are several of them, in the warehouse."
Lao He knows the equipment well.
"That's good. Our spinal external fixator experimental product has not left the factory yet. Once it leaves the factory, I will contact you and courier it. We will do the external fixation insertion surgery. You have to help with daily adjustments." Yang Ping said simply. Talk about division of labor.
Lao He said: "Well, in the afternoon, I have arranged a time for you to give lectures to everyone. At that time, the Ph.D.s from Union Medical College will be responsible for your project."
In the kitchen, Lao He's wife sent a message asking for Lao He's help.
"You go and do your work, I'll go around by myself."
Yang Ping looked around the laboratory yard by himself, and several doctors came to strike up a conversation.
(End of chapter)