Chapter 627 A Blank Paper
Yang Ping's strong self-confidence is like a unique label that Tang Shun can recognize at a glance.
The same was true in Tokyo at that time. This self-confidence made all Japanese people feel as if they were dehydrated. To this day, stories about Yang Ping are still circulating among medical students at the University of Tokyo, and there is also a comic about him.
Following Yang Ping were Song Zimo and Xu Zhiliang, whom Tang Shun was also familiar with.
When he was in Japan, Tang Shun worked as their personal translator for a few days and became friends with them.
There are two foreigners following behind. If the guess is correct, the young one with the red nose is Robert, and the slightly older one is August.
Before returning to China, Gao Qiao and Tang Shun introduced these two world-famous figures who studied under Yang Ping.
Of course, it was Takahashi's idea to come to Sanbo. Takahashi said that joining Yang Ping's team has a bright future.
Even Takahashi knows this, but I, Teacher Tang, don't know it.
It’s just that in the eyes of my teacher, Mr. Tang, a career must achieve two functions before it can be called a career. One is to realize one’s ideals, and the other is to earn money. If one of these is missing, it will be incomplete.
"Hello, Dr. Tang!" Yang Ping stretched out his hand.
Holding Yang Ping's hand, Tang Shun, who had always been confident, was a little panicked. He didn't expect that the person who came to greet him would be Yang Ping himself. How could a man who could make Takahashi and all the proud people in Tokyo bow to him, run away by himself? Come down and greet.
However, Tang Shun's nervousness was unnecessary. Apart from the confidence in his body, Yang Ping did not give him any sense of oppression. Instead, he felt relaxed and at ease.
"This..." Yang Ping did not dare to casually determine the identity of the girl next to Tang Shun. After all, the relationship between the characters was complicated.
"This is my girlfriend, you can call her Qianxia." Tang Shun introduced generously.
Chinatsu Suzuki, a first-year undergraduate at the University of Tokyo, bowed shyly: "Please take care of me."
——
The office of General Surgery Yang Ping.
Everyone sat down, Yang Ping made friends with tea, and the aroma of Longjing floated in the office.
Tang Shun's Japanese girlfriend was accompanied by Tang Fei and took her to visit the hospital.
This little girl from the University of Tokyo said goodbye to Tang Shun in a sweet voice and followed Tang Fei to visit Sanbo Hospital.
After a few pleasantries, Yang Ping got straight to the point.
"Dr. Tang, we are currently launching a new project - stem cell cultivation of muscles. We want to use this research to open up a new world in the field of organ cloning. We intend to invite Dr. Tang to join us."
Song Zimo had already chatted with him many times on WeChat, so there was no need for any preparation.
"I would like to know Professor Yang's views on this topic?"
Tang Shun picked up the tea and tasted it slowly.
Robert and August blew into the cups for a few times. After the tea cooled down, they swallowed it in one gulp. Then they stared at the empty cups in a daze, waiting for Xu Zhiliang to add tea.
"This is part of the information on our project. You can take a look at it first." Yang Ping said, and Song Zimo handed the information to Tang Shun.
Tang Shun flipped through page after page: "Taking two technical routes at the same time requires huge human and financial support? It's unrealistic."
Yang Ping shook his head: "The last thing we need to worry about is money. There is a special foundation to provide funds for our research. Now the funds on the book have exceeded one billion. This is just the beginning. You are familiar with the Anning Group, the Guo Family in Southeast Asia, etc. , are all our funding providers.”
Tang Shun was a little shocked that a hospital laboratory actually had so much scientific research funds, but he calmed down immediately. Anning Group is an emerging consortium. Guo Group has no tradition of funding medical research before, so continued funding may be a problem.
Tang Shun has seen too many things that start before the end and end at the end. He initially talked about how much money to provide, but after the first tranche of funds was received, there was no further progress. Either the fund donors stopped paying attention to the matter, or the company itself was in financial difficulty or even closed down.
in the country, enterprises fund scientific research institutions and lack tradition, so it is difficult to have sustainability.
"I'm worried about the durability of the project funding?" Tang Shun said clearly.
Academicians are all straight men. They go straight to the point, saving time and improving communication efficiency.
"I understand your concerns, what do you think of the Duke's Fund?"
The Duke's Fund?
Europe's low-key and secretive aristocratic fund has funded many projects, among which Nobel Prize winner Mr. Maninstein received funding from this fund.
Tang Shun was surprised that the Duke's Fund would also provide him with funds.
"One billion euros will arrive soon. You can talk to Mr. August in detail about the Duke Fund later." Yang Ping said calmly.
Tang Shun's heart has begun to stir. There is one billion yuan in his account, and one billion euros to follow. This kind of financial resources can fully support this huge project.
I never imagined that a hospital laboratory could have such fund-raising capabilities.
Tang Shun thought that only laboratories at the University of Tokyo or prestigious American universities had such fundraising capabilities.
"If Dr. Tang is still worried about funding, I can also tell you that in the future, our laboratory will be backed by the largest supporters in the world, no one can compare." Yang Ping was lying.
"What do you mean?" Tang Shun didn't understand.
"Our country! I don't like to talk about feelings, but I will talk about feelings with Dr. Tang today. If the conditions are equal, I hope Dr. Tang will choose us. Although this is only a hospital-level laboratory, we can do it in the future To build it into a national-level laboratory, the world's top laboratory, with our country's economic strength and emphasis on science and technology, coupled with our strength, I think this is not difficult. ”
"Our first topic - a new technology for spinal external fixation. We cooperated with Peking Union Medical College and Nandu Medical University and successfully completed the experiment within a few months. Now we are launching three-phase clinical trials in Europe, the United States and Japan. It is no exaggeration to say that this It is a world-class topic. In this field, we deserve to be ahead of Europe, America and Japan.”
When Yang Ping should be proud, he will not be uselessly modest.
Tang Shun naturally knew about the new technology of spinal external fixation. What the Japanese only dreamed of doing, Yang Ping did it.
Tang Shun has carefully studied Yang Ping's spinal external fixator. The technology content is very high and there are many medical and engineering problems that need to be overcome.
It took many years and a team of hundreds of people to develop a spinal orthopedic device jointly produced by the Biomechanics Laboratory of Dongda University and the Affiliated Hospital of Dongda University, but there was still no progress.
Presumably Yang Ping's team will also spend a long time, but I was quite surprised when I just heard that it took a few months.
Tang Shun wanted to know how many people's team spent several months to achieve results.
"Professor Yang, I would like to know how many people are involved in the spinal external fixation research team?"
Tang Shun feels that the core team already has more than a hundred people, and trial and error alone is a huge project. This kind of project should be completed by the collaboration of several universities and hospitals. "Actually, this technology is just a small work of ours, and the core team is just three of us!"
Yang Ping said slowly.
Tang Shun now felt huge waves in his heart.
Spinal external fixator, a world-class technology, has only three core members?
Only Yang Ping, Song Zimo and Xu Zhiliang?
Tang Shun believed this, because people like Yang Ping didn't need to brag, let alone brag to themselves.
Tang Shun has always admired Musk. He has read his autobiography "Iron Man of Silicon Valley" and still remembers Musk's rocket team. Dozens of unorganized guys in slippers actually developed advanced rockets.
Now that I see Yang Ping, I can't help but think of Musk, and then feel a sense of admiration.
"Can I visit your laboratory?" Tang Shun was a little excited.
"Of course, our laboratory is upstairs, which is very convenient." Yang Ping knew that he was already moved.
Everyone took the elevator to the laboratory. The stem cell laboratory occupied an entire floor. Some graduate students were busy in the laboratory, some were playing table tennis in another recreation room, and some were drinking coffee and reading magazines.
The members of the laboratory are also very casually dressed, many wearing T-shirts and shorts, looking very relaxed.
This scene once again gave Tang Shun a very familiar feeling, that is, a photo: behind is an assembled rocket, with a dozen people taking a group photo of themselves relaxed and comfortable, wearing T-shirts, jeans, and slippers.
This rocket team, which has the spirit of the Internet in Silicon Valley, has the courage to explore, keep trying and making mistakes, is not afraid of failure, and finally completes the research and development of new rockets.
"There is a recreation room here. You can listen to music, exercise, drink tea or coffee here at any time. No one will supervise you, and no one will ask you to work. You can arrange your own work freely -" Yang Ping introduced how to work in the future.
Tang Shun nodded. He just liked this kind of relaxed and tolerant working atmosphere. He didn't like the ascetic and hateful atmosphere of the University of Tokyo laboratory.
"In terms of equipment, we are short of a cryo-electron microscope and need to borrow equipment from Nandu Medical University. However, we plan to buy a cryo-electron microscope, which can save experimental time."
The team moved in the corridor, and Yang Ping introduced the laboratory equipment.
The lack of dedicated cryo-EM is normal. Even at the University of Tokyo, cryo-EM is not privately owned by a certain research team, but is shared by everyone, and everyone takes turns using it.
"If I take the 3D printing route, I wonder where Professor Yang should start?"
Tang Shun was already very excited, he found this place to his liking.
"Both routes are actually very difficult. The 3D printing route is easier to control. For example, stem cells cultivate muscles. The cultivation method may not be able to obtain the fine structure you want. For example, a designated part needs a thicker artery to communicate with the recipient. Area connection. 3D printing can easily achieve this kind of customization, but 3D printing requires a very detailed study of the anatomy of the target organ. To complete real 3D printing, the collected anatomical data is massive, and it is estimated that supercomputing will be needed. To complete this level of calculation and printing, the total length of a muscle's nerves, arteries, veins and lymphatic vessels can circle the earth without any problem. This is the reason why 3D printing cannot complete simple cartilage printing and cannot be copied. Fine anatomy is just like a model of an airplane, but the internal engine cannot be copied, and of course it cannot fly into the sky.”
"The 3D printing route is much simpler than the cultivation technology at the biological stage. It only needs to cultivate a large number of various living cells, and then use these living cells as raw materials to complete the printing of organs. There is no need to decipher the various human body controls in the organ formation process. , and the whole project of the cultivation route is larger. It completes the construction of organs at the biological level from beginning to end, and invests more in research on human gene expression and regulation. Which one is better is still unknown. I used to think that cultivation is better, but later I thought that 3D Printing is better, and then there is no difference between the two. Which of the two routes will make a breakthrough first?" Yang Ping briefly expressed his understanding.
This is the case with scientific research. Sometimes when multiple routes advance in parallel, the one who makes the breakthrough first will naturally gain an advantage.
Tang Shun agreed with Yang Ping's understanding.
An organ is more complex than imagined, which is why an apple can be easily grown on a tree, but humans cannot copy an apple.
The two routes solve the problem in different ways. One is to figure out the information contained in the seeds, and the other is to figure out the information contained in the apples.
Tang Shun admires first principles, that is, reducing things to their essential essence.
If stem cells are to truly succeed in cultivating muscles, they must start from scratch. We can only learn from other scientific research results, and we must not conduct research based on other results.
If you want to print muscles, you must conduct the most thorough and complete study of the muscle's anatomy.
Lay the foundation again and build the house again.
"My laboratory cooperates with Nandu Medical University and Nandu University of Technology, borrowing the cryo-electron microscope of Nandu Medical University and the supercomputer of Nandu University of Technology, and plans to slice single-layer cells of the muscle, and then use the electron microscope to scan the entire muscle to conduct a fine three-dimensional composition to obtain The subtle anatomy of muscles." Yang Ping said the plan.
Scanning the slices of a single layer of muscle cells is a huge and complicated task, and the data is massive.
Tang Shun stopped. This was the first time he heard that someone had to do such a massive amount of work.
The professional division of labor has made everyone "very lazy", and they always like to use it for non-professional matters. They always use it directly without knowing whether it is suitable.
Therefore, those engaged in stem cell research will never really study the anatomy of the target organ, and those who study anatomy will not study the structure of the organ from the perspective of stem cell cultured organs.
Yang Ping wanted to start from multiple disciplines and conduct the most basic research again, which coincided with his own ideas.
But can the human and financial resources support it?
It would be too forward-thinking to think about this anymore. It seems that this career has already met my first requirement.
What about the second requirement?
treatment?
Tang Shun is a person who is very sensitive to money. He does not want to engage in scientific research with a meager salary, or worry about life while doing scientific research.
"I would like to know how I would be treated if I stayed?"
Tang Shun is very direct.
Yang Ping didn't speak, and no one in his entourage spoke. Tang Shun smiled: "Am I too direct?"
"No! You are very frank. As for the treatment, I don't think we need to talk about it. We are ready, Song Zimo?" Yang Ping also smiled.
Song Zimo presented a document board with only a blank piece of paper and a pen on it.
A blank piece of paper, what does that mean?
Tang Shun didn't understand.
Yang Ping said easily: "Write down your treatment and all your requirements on this piece of paper, and I will do it!"
(End of chapter)