Chapter 20 National Innovative Drug Support Center!
“Excessive, really too much!”
“1800 subjects, what kind of new drug requires so much clinical data?!”
“ Are we treating diabetes? 1,800 clinical samples!”
In the office, even the always good-tempered Ren Xiaomin couldn’t help but curse after seeing the trial plan.
In fact, with the exception of some drugs for specific diseases, the State Pharmaceutical Administration has only one basic requirement for the number of people in phase III clinical trials of most drugs, that is, the number of people in the clinical trials should not be less than 300.
In actual application, the approximate range is controlled at 300-2200 people.
For example, drugs for the treatment of diabetes require a longer period of time and more subjects to fully evaluate the efficacy and safety of the drug because individual patients vary greatly and are chronic drugs taken for a long time.
Another example is psychiatric drugs. Because the efficacy evaluation is more complex, more subjects are needed to ensure the reliability of the results.
But,
Drugs like "Avatrombopag Qingshan" are specifically designed to increase platelets. Because the treatment is highly targeted and the efficacy is easy to evaluate, the number of samples required does not need to be too many!
I didn’t expect that...
“No, I have to go to the review center and ask how they got the data of 1,800 people!”
“1,800 people. , let alone find 1,800 people who meet the enrollment requirements, I’m afraid it’s not easy to even find 1,800 patients with blood diseases!”
“I must go, I will go now!”
As he spoke, Ren Xiaomin was really angry and was about to walk out with the clinical trial documents in hand.
Zhang Yang calmed down at this time, and even couldn't help but sigh when he saw Ren Xiaomin's angry look.
"Brother Ren, they are really going too far to force your good temper to this point."
"However, it is useless for you to find an explanation for this matter, the judges The center complied with the laws and regulations, and there was no fault at all.”
“What’s more, someone must have been instigating this matter, otherwise it would have been impossible to set this number!”< br>
"Huh?"
Ren Xiaomin was stunned for a moment, and suddenly thought of a series of recent price reductions by pharmaceutical companies.
After a while, his face turned slightly pale, and his eyes showed a hint of disbelief.
“Are you saying...or is Ding Jian Ding always causing trouble behind the scenes?”
“Did he influence the judging center?”
The words fell, and before Zhang Yang could answer, he already had the answer in his heart.
Based on his understanding of Mr. Ding Jian, he does have this ability.
Suddenly, his face darkened, and most of the anger in his heart was extinguished in an instant.
If it is Mr. Ding who uses the relationship, then this matter will be difficult.
“Yes, I estimate that Ding Jian is the one behind it in all likelihood.”
Zhang Yang also nodded slightly to confirm.
After a moment, he took a deep breath and sighed:
“I originally thought that he would hit us seven inches when he released the news about our financial constraints, but I didn’t expect that he would There is a chain plan.”
“18. 00 subjects, 1,800 samples. In this way, even if we cancel the enrollment subsidy, the cost of these people’s examinations alone will drag us to death!”
“I still underestimated him, Now we are riding a tiger and it’s hard to stop.”
Ren Xiaomin now fully understood the impact behind this incident, and his expression became a little depressed.
For 1,800 people, the inspection cost is at least 25-30 million yuan, which is definitely not something they can afford now.
More importantly, 1800 subjects, how much time does this take to complete!
Five years?
Seven years?
The atmosphere in the office became sour as both men realized the seriousness of the problem.
The tens of millions of inspection fees are just a drop in the bucket for other pharmaceutical companies, and the time of a few years is non-existent and completely affordable. "Zhang Yang..."
After being silent for a long time, Ren Xiaomin breathed out gently. No matter how difficult the matter is, he must find a way to face it.
Zhang Yang nodded in response, he knew what Ren Xiaomin wanted to say.
At this moment,
A clear ringtone suddenly rang in the office. When I saw the call, it turned out to be He Youcai from Beifeng Pharmaceutical!
A trace of surprise flashed in Zhang Yang's eyes. At this time, He Youcai from Beifeng Pharmaceutical suddenly called?
What is this going to do? !
Taking advantage of the situation? !
After hesitating for a moment, he picked up.
He Youcai's voice came from the other end of the phone.
“Mr. Zhang, I haven’t contacted you for a long time.”
“After I was scolded by you last time I met you, I was enlightened and realized it. The company's 'Aoyama Awa' has made more changes Detailed evaluation. ”
“Finally, now we have fully understood the value of your company, Qingshan Afa, and after the resolution of Mr. Ding and the board of directors, we have decided to re-quote 75 million!”
"I hope to acquire your company's 'Qingshan Afa' at a price of 75 million!"
75 million!
Hearing the end, Zhang Yang was very surprised. He didn’t expect Beifeng Pharmaceutical to be so generous this time.
But as soon as I thought about it, I couldn't help but feel a chill in my heart.
This Ding Jian is really not simple!
Not to mention the ability to bend and stretch, all the strategies are linked together,
And the timing of this quotation is really good!
I just learned that the number of patients in the third phase of clinical trials has been increased to 1,800, so I must be extremely worried!
At this time, he took the initiative to contact me, and his attitude was so low, and he even raised the price to 5 million higher than Hengrui before!
Price of 75 million,
Asking himself, the moment he heard the price, he was also moved!
What a skill!
But he soon returned to normal.
Zhang Yang knows very well that
the current difficulties he is facing are all due to Ding Jian. Now that he is making a hypocritical offer, can he still let them succeed?
impossible!
However.
This time Zhang Yang was not in a hurry and said in a low voice:
"Mr. He, I need to think about it."
"Okay, no problem!"< br>
"However, you have to hurry up, Mr. Zhang, the price of 75 million is high enough."
Hang up the phone, Zhang Yang exhaled heavily.
Sell, he will definitely not sell it to Beifeng Pharmaceutical!
But!
If you don’t sell to Beifeng Pharmaceutical, you will have to sell it to other pharmaceutical companies after all!
There is no way, he has no funds to continue to advance.
Besides, he can’t afford to delay it.
What was also obtained from the simulator was the patent for "ITG Human Recombinant Generating Hormone". If the problem of "Qingshan Avatrombopag Tablets" is not solved, and if it is stuck here, then all the following problems will be solved. Things get stuck!
This is not what he wants!
Then sell it!
The office fell into silence again.
Ren Xiaomin looked at Zhang Yang and could feel his unwillingness and empathize with him.
After five minutes, he seemed to have made a huge and difficult decision, and said slowly:
"Zhang Yang, if you are really unwilling and don't want to sell, I will still give you the chance. There is a last way.”
“Do you know the ‘National Innovative Drug Support Center’?”
……
PS: Thank you Hand2016 for your monthly vote.
Thank you Lingkong & Maozi for the 2 monthly passes.
Crab crab.
(End of this chapter)