Chapter 21 Grain Seedling Project


Chapter 21 Grain Seedling Project

National Innovative Drug Support Center?

Zhang Yang raised his head and looked at Ren Xiaomin. This name was a bit niche and he was really not familiar with it.

Ren Xiaomin exhaled softly and explained:

“This is a new department established under the leadership of the Ministry of Science and Technology last year. You usually focus on drug research, so it’s normal that you haven’t heard of it.”< br>


"Simply put, its purpose is to support the research and development of domestic innovative drugs."

"As you know, the development of domestic innovative drugs is currently slow. Compared with developed countries abroad, we are almost at the bottom. Level."

Zhang Yang nodded slightly, Ren Xiaomin was talking about the reality of the domestic pharmaceutical industry.

On the one hand, domestic research on basic life disciplines is weak, with obvious gaps in technology and theory.

On the other hand, compared with the huge investment in research and development of innovative drugs, long cycle time, and extremely high risks, the domestic production of generic drugs and proprietary Chinese medicines not only has high profits, a short cycle, but also almost no risks.

Therefore, except for a few large pharmaceutical companies such as Hengrui and Baekje, almost no one is willing to do such a thankless task.

This has also resulted in the current slow development of the domestic innovative drug industry, which has become the biggest shortcoming in the country.

Ren Xiaomin continued:

"The country has also noticed this, established an innovative drug support center, and launched an incubation program called the 'Grain Seedling Plan'."

"Grain Seedling Project?"

"Yeah."

"To put it simply, all domestic pharmaceutical companies' innovative drug projects can apply to participate in this program. As long as they pass the approval of the expert group of the support center, they can get a considerable amount of incubation funds. It is enough for the new drug to complete clinical trials. "

"And no matter whether the new drug can be clinically launched or not, this money does not need to be repaid."

Zhang Yang looked slightly stern, but did not speak. Waiting for Ren Xiaomin to continue talking.

“Of course, for this reason, the review of the ‘Grain Seedling Project’ is very strict. For more than a year, the pass rate of the published data is only 9.8%.”

"Furthermore, the 'Grain Miao Plan' also has a mandatory requirement, which is that once you join the 'Grain Miao Plan', if a new drug is successfully marketed in the future, the Medical Insurance Bureau has the right to unilaterally include this innovative drug in the centralized purchasing list,< br>
And the purchase price will not be higher than 30% of the retail price, or the purchase price will not be higher than 200% of the production cost. "

"In other words, if our 'Qingshan Avatrombopag Tablets' are launched in the future, if the retail price is 1,000 yuan, then the Medical Insurance Bureau has the right to purchase it at the lowest price of 300 yuan. ”

“The term of this agreement is 10 years.”

Zhang Yang completely understood, and there was no obvious fluctuation on his face.

To put it simply, this is a gambling agreement.

The support center can select the innovative drugs they see for investment. If they fail to pass clinical trials, then the money will be considered a loss for the company, and the pharmaceutical company can at least accumulate some experience from it.

If you are lucky enough to pass the third phase of listing, you can recover some of the initial costs from later drug purchases.

This method is quite fair. It doesn’t matter who loses or gains. It can even be considered a win-win situation.

However, the situation of "Aoyama Avatropopa" is slightly different.

Zhang Yang is very confident that with the therapeutic effect of "Qingshan Ava", it is only a matter of time before it completes the third phase of clinical trials and goes on sale.

Once you join the "Grain Seedling Project", it is obvious that there will be a certain impact on profits and pricing of new drugs after they are launched in the future.

Ren Xiaomin on the side also saw Zhang Yang’s thoughts:

“So Zhang Yang, you have to weigh the gains and losses carefully.”

“And, I must remind you, Although we all think that the clinical phase II data of 'Qingshan Ava' has a high probability of passing the 'Grain Miao Project', but if we submit the application and it is not approved in the end,"

"Then we will really be riding a tiger in the future."

Zhang Yang nodded heavily and began to think seriously. After a few minutes, he, who had been immersed in thought, moved his body slightly and seemed to have made a choice.

"Brother Ren, I have decided to apply to join the 'Grain Seedling Project'. I think as long as the people in the support center are not blind, they will not reject our application."< br>
“Although they will take advantage of them, at least the Medical Insurance Bureau also serves the common people. It is better for us to give profits to the common people than to let those pharmaceutical companies take advantage!”

"Okay, then I will prepare the materials now, and I should be able to submit the application tomorrow."

Ren Xiaomin agreed immediately.

......

Just when Zhang Yang and Ren Xiaomin made their decision, other pharmaceutical companies also noticed the discrepancies in the approval document for the Phase III clinical trial of "Qingshan Avatrombopag Tablets" Clues.

Every pharmaceutical company was surprised and delighted. With a trial number of 1,800 people, everyone knew that Qingshan Pharmaceutical was forced to a dead end and it was impossible to continue to promote the third phase of clinical trials.

There was an undercurrent surging for a while, and everyone wanted to take advantage of it.

What everyone expected was that Zhang Yang was not in a hurry and seemed not to be affected by the Phase III clinical approval at all.

While everyone was puzzled, two days later, a press release about the application of "Avatropopa Green Mountain" to join the "Grain Seedling Project" suddenly appeared on the Internet.

Many pharmaceutical companies now understand that Qingshan Pharmaceutical originally tried to obtain funds through the "National Innovative Drug Support Center", but everyone is still not optimistic about it.

Everyone knows that it is very difficult for the "Grain Miao Project" to get approval, and very few can actually get support funds. Although the clinical data of "Qingshan Avatrombopag" is good, the final result is still unknown.

In the office of Beifeng Pharmaceutical, Ding Jian also learned the news.

“It’s true that I can’t shed tears until I see the coffin!”

“I thought I was driving you to a dead end, but I didn’t expect that you would resort to this trick!”

“ You really would rather lose the next ten years of profits than sell the patent to me! What a two-eyed wolf!"

In the office, Ding Jian said coldly, and everyone could hear the meaning in his words. Very unhappy.

Not only Ding Jian, but also He Youcai on the side could not help but sigh heavily, full of disappointment.

Recalling that last night when the number of people in the Phase III clinical trial had just come out, he immediately called Zhang Yang. Zhang Yang’s attitude originally made him think that the matter should be done, but he didn’t expect...

Hey , something unexpected happened again in the blink of an eye!

But now is not the time to sigh. The most important thing right now is what to do next?

“Boss? Do you think we should contact Zhang Yang again?”

"Their clinical phase II data of 'Qingshan Avatrombopag Tablets' is very good. I said what if...

What if they really pass the 'Grain Miao Project' and really get incubation from the support center Funds, then all our efforts will be in vain, and there will really be no hope for this matter!"

Ding Jian's face became even more gloomy.

It took a full two minutes before he slowly shook his head and said in a deep voice:

"Don't worry, the more critical the moment, the less likely we are to reveal our flaws! You have to know, they are already here The final struggle!”

As he said that, a fierce look flashed in his eyes:

"Besides, do you think I only have people in the judging center?"

He Youcai was shocked.

……

(End of this chapter)

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