Chapter 113 The second clinical phase of the hepatocyte activator clinical trial ends! (Big update for the Ring Empire!)
Zhang Yang looked around, and within two seconds, his expression suddenly became a little strange.
How could he not know about this "LivClearX"... This is the lowest 50% version of the "hepatocellular activator"!
He said calmly with a sullen face:
“What’s wrong?”
“It’s nothing!”
“Although this drug is mainly promoted to treat fatty liver, one of its therapeutic effects is to ‘prevent the progression of cirrhosis’. Therefore, we have several patients here who did not participate in the trial. I want to buy it and try it.”
“I just thought that if you know about this medicine, you can tell me about it. If a patient asks me about it, I can give you some advice.”
“Now I think this drug from Novartis is about to finish its third phase of clinical trials, and it is estimated that it will be on the market in less than two months. There are several drugs. The patients are even looking for someone to go to the United States to purchase on their behalf..."
Zhang Yang was slightly taken aback when he heard this, but he still understood these patients and their families.
First of all, the "hepatocyte activator" was not very effective before and there were few clinical places. It is normal for patients to be anxious.
Secondly, if the elderly or children are really sick, everyone will want to buy and try some good medicine when they hear about it. This is human nature.
However.
At this time, he really felt like laughing but didn't dare to laugh.
My drug with 70% efficacy is already advancing to the second clinical phase. After two or three more modifications, it will reach 100% efficacy in the third clinical phase.
I don't expect my own medicine, so I went far away to buy the younger version of the "hepatocellular activator"... Isn't this exporting to domestic sales?
Fortunately, 50% of "LivClearX" is somewhat effective, at least it can stabilize liver cirrhosis and prevent it from getting worse.
The most important thing is that this is our own product, so we can't persuade others not to buy it...
"Hey, Director Chen, please persuade me, we'll promote liver cell activation. The effect of the medicine is definitely better than this.”
“But those who can purchase it are not ordinary people. If you really want to buy it, don’t stop me. This medicine is still somewhat effective.”
Chen Wen was stunned for a moment, then nodded.
"Okay, then I will do as you say!"
......
The "liver cell regeneration activator" finally showed results after long-term use The news inspired the entire Tsingshan Pharmaceutical R&D team.
Zhang Yang has also basically figured out the treatment cycle and effect of this drug on human liver cirrhosis.
On November 7, under the guidance of Zhang Yang, the effective activator ingredients of "Hepatocyte Activator" were improved again, and the therapeutic effect was increased from 70% to 75%.
On December 7,
the three-month clinical phase II of the "hepatocyte activator" ended, and all patients received comprehensive clinical data for the first time.
A total of 94 people were recruited for the second clinical phase, of which 54 were in the experimental group and 40 were in the control group.
Among the 54-person test group, only three patients had poor response to the activator, and the effective response rate to the drug reached 94.4%.
The results of transaminase, alpha-fetoprotein, liver elasticity, and B-ultrasound of the remaining 51 people who responded improved, among which the transaminase, alpha-fetoprotein, and bilirubin indicators returned to normal.
Imaging B-ultrasound, liver ejection, and CT have improved slightly, but still need to be observed.
The indicators of the 40 people in the control group had no significant changes compared with three months ago, and three of them even developed hepatic ascites and gastrointestinal bleeding during hospitalization.
The obviously different clinical results quickly spread among the patients. Now everyone can see it. After taking Qingshan Pharmaceutical's "hepatocyte activator" for three months, it actually has a positive effect on the liver. Hardening works!
The news that "Liver Activator" is effective immediately spread to all major liver cirrhosis patient groups, inspiring countless patients!
Suddenly, the patient group started a heated discussion!
"Old Wang, are you telling the truth? Can Tsingshan Pharmaceutical's new drug really reverse liver cirrhosis?"
"That's not true, but everyone I know who entered the trial group The patients’ alpha-fetoprotein, transaminases, and bilirubin have all dropped, and no one has suffered from liver ascites or internal bleeding in the past three months!”
"Holy crap! I know that several patients with advanced liver cirrhosis participated in the trial? I looked like I was about to die when I was enrolled in the group. Is it really okay? Even hepatic ascites didn't appear?!"
"I can still lie to you! Come to the hospital to see it yourself, everyone is clamoring to participate in the third phase of clinical trials!" The evaluation of the subjects was relatively subjective,
Three days later, Tsingshan Pharmaceutical released the complete clinical phase II data into the clinical trial data of the State Drug Administration. All pharmaceutical companies and individuals can view the public clinical data!
At the same time that Zhang Yang announced the data, on the other side of the ocean, "LivClearX" represented by Novartis also completed its Phase III clinical trial.
The clinical phase III data of LivClearX for fatty liver is still excellent. On Twitter and Titok, the praise and expectations for this fatty liver drug are getting louder and louder.
However.
Novartis was not happy because of the praising public opinion on the Internet. Gradually, even President Green felt that the public opinion seemed to be gradually going astray.
In the office, President Green is sitting on a large and soft leather sofa. Opposite the coffee table are two vice presidents, Klein and Friedman.
Friedman is in charge of marketing and sales. This time he is also fully responsible for the promotion and promotion of new drugs in "LivClearX".
Green put down the coffee cup in his hand and frowned.
"Friedman, you must have seen a lot of comments about our new drug 'LivClearX' on the Internet. Now both netizens and the media are assuming that 'LivClearX' was developed by us. I feel this Very bad.”
"Now that we have passed the third phase of clinical trials and are about to go on sale, I think we should stand up and clarify this matter."
Friedman couldn't dodge Green's gaze.
He noticed this three months ago, but it is obvious that online public opinion is very effective in promoting Novartis and "LivClearX".
He delayed it for three months, but now he can no longer delay it.
"Mr. President, I agree with your point of view."
"But I think the public opinion on the Internet is of great help to us, and we have never publicly promoted that 'LivClearX' was developed by us. This impression is just the media and netizens themselves."
"Besides, no pharmaceutical company will take the initiative to promote the name of its partner, such as Johnson & Johnson's well-selling asthma drug Mepu." ran, he will also tell consumers that the drug comes from Japan's Otsuka Pharmaceutical."
"There is nothing wrong with what we do, so we don't need to clarify."
Green's attitude is very firm. , shook his head:
"Friedman, I understand your emphasis on LivClearX, but Japan is different!"
"This drug comes from China. As you know, the information about Qingshan Pharmaceutical can be found in the FDA filing materials. Once it is announced by other pharmaceutical companies on the Internet, it will undoubtedly have a very bad impact on us."
< br>“So, we must clarify this matter as soon as possible, and we cannot continue to ferment it.”
Friedman stared at Green for several seconds, and finally lost.
A trace of disappointment flashed in his eyes:
"Okay, President, I will follow your arrangement, but I hope it will take a little longer!"
"Our 'LivClearX' is about to be launched. We can wait until it is launched and everyone has used it and experienced the effect before making it public. This way we can minimize the company's losses. What do you think?"
Green Originally he wanted to refuse, but after seeing the look in Friedman's eyes, he hesitated for a few seconds and nodded.
“Okay, let’s do what you said.”
As he spoke, Green picked up the coffee cup again and took a sip. He did not end the conversation, but changed the subject.
“Okay, next we will focus on discussing the selling price of ‘LivClearX’!”
"One is the selling price in our market, and the other is the purchase price we gave to Qingshan Pharmaceutical."
"Before, we only signed a priority agency contract with them. Now that the three clinical phases have been approved, It’s time to talk about this.”
“Friedman, tell me what you think!”
……
ps: Chapter 1 added today, type. There are 2 more chapters left for the reward.
(End of this chapter)