Chapter 136 The price of Clobazam is announced (please subscribe!)
Ren Xiaomin’s teasing brought the two people’s “walk after dinner” project to an end soon.
Ren Xiaomin was getting older and came to the lounge to take a nap, while Zhang Yang returned to the office and started processing some documents.
At present, Qingshan Pharmaceutical has several drug projects in its hands, among which "Clobazam" is one that is nearing completion.
The production qualifications have been obtained, and the original drug can be produced stably. The next step is to establish a special circulation agreement with the hospital. After all, this is a controlled drug.
In addition, the price of clobazam has also been determined.
The price of clobazam has been discussed by Zhang Yang, Ren Xiaomin and Wei Tian before. The purchase price of generic drugs in India is 350 yuan, without reimbursement;
The purchase price of overseas original drugs is 700 yuan, also without reimbursement. .
Considering that the production cost is not high and there are no patent fees, the only production materials are sent by Novartis, but there are certain expenses for approval and storage.
Zhang Yang will eventually set the retail price It costs 350 yuan per box, which is the same as the generic drugs produced in India.
However,
after being included in the medical insurance, the medical insurance will reimburse 60%, totaling 210 yuan;
the individual will bear 40%, which only costs 140 yuan.
140 yuan.
For domestic patients, the emergence of "Qingshan Clobazam" not only solves the problem of being unable to buy medicines in China, but also reduces the price and allows them to eat things that they could not even imagine before. Original research "Clobazam"!
Of course,
Zhang Yang has no intention of expecting "Clobazam" to make money. There are only 12,000 patients in total. How much money can it make?
The price of 350 yuan per box can cover the cost or make a slight loss, so he can continue to produce.
Soon, his eyes fell on the "Kidney Toxin Clearing Dialysis Needle".
Just two to three months after the "Clobazam" incident, the previous "Nephrotoxic Clear Dialysis Replacement Injection" clinical phase one and two trials in the United States and India have also come to an end.
What Zhang Yang didn't expect was that 60% of the "Kidney Clear Dialysis Replacement Injections" did not cause any trouble in the United States. On the contrary, everything went smoothly.
According to the Phase I clinical data provided by Novartis, the "dialysis" patients participating in the trial are in good condition, and no one has suffered serious abnormal reactions.
GlaxoSmithKline in India is conducting the first and second phases of clinical trials simultaneously.
The data provided are more and more comprehensive. Although there are also no deaths, in only Even with a toxin clearance rate of 60%, a dozen patients still developed obvious symptoms of heart failure. The toxins entered the body and affected the organs.
This is also the reason why Zhang Yang is entangled and worried about testing in the country.
Fortunately, the most difficult stage was over. According to the scheduled plan, Zhang Yang immediately ordered Wei Tian to provide Novartis and GlaxoSmithKline with the ingredients of the "Kenduqing Replacement Injection" that had been improved half a month ago and had an effective clearance rate of 70%. .
Whether it is the FDA or the Indian market, a new round of clinical trials will be carried out next, and it is time to provide 70% of the improved drugs.
Novartis and GlaxoSmithKline quickly received samples. At the same time, FDA Novartis's clinical phase II began, and GlaxoSmithKline's clinical phase III in India also kicked off.
……
USA, Mayo Hospital.
To be precise, it should be called the Mayo Clinic.
Among the Chinese middle class, there is a widely circulated saying that if Huaxi and Xiehe cannot save you, then try Mayo.
If Mayo can't do anything, then he can only wait to die.
Mayo Hospital is somewhat unfamiliar to more than 1 billion ordinary people in China, but it is indeed a globally recognized top hospital and the world's number one.
Especially in the treatment of gastrointestinal diseases, kidney disease treatment, and endocrine disease treatment, it is definitely the world leader.
Stephen made an appointment with William, a well-known nephrologist in the United States, half a month ago. After waiting for about ten minutes, he was allowed to enter the clinic.
"Stephen, I haven't seen you for a long time. How are you? Are you feeling well lately?"
Stephen is a uremic dialysis patient and a professor of semiconductors at the University of Minnesota.
Dr. William is his attending doctor, and the two have a pretty good relationship in private.
"Doctor William, I haven't seen you for a long time."
"However, I don't feel very good."
"The quality of dialysis in the past month has been a bit bad. I checked the key indicators a week ago and the blood potassium level was very high. I think I need to solve this problem. .”
William has seen the blood report Stephen made a week ago on the computer. It does not mean that patients with uremia will be fine after undergoing dialysis. On the contrary, dialysis will also bring many adverse reactions and complications.
High blood potassium concentration is a very common symptom. If not controlled, high blood potassium concentration will affect the heart and digestive system.
However, before he could speak, Stephen said:
"Besides this matter, I also want to ask, how long do I have to wait for a kidney source?"
Dr. William was originally attending I was quickly entering medication information on the computer, but suddenly stopped when I heard these words. Come down:
“Professor Stephen, I don’t know this either.”
“Too many people in the United States are waiting for kidneys. Donated kidneys are simply not enough, unless... you have Special channel of kidney sources ”
Hearing this, Professor Stephen looked bitter.
Although he is a university professor, he is not a powerful person with good hands and eyes. It is almost impossible to buy a kidney source through special channels.
Seeing this, Dr. William continued:
“Furthermore, you had a kidney transplant a year ago, but just six months later, the transplanted kidney suffered from severe excretion. In the end, surgery will have to be performed to remove it. "
"So, in your case, I suggest you give up transplantation for a short time and just go for dialysis. Dialysis technology is now very mature, and patients who have been on dialysis for more than 20 years can do it. A lot too.”
Professor Stephen sighed slightly. Kidney transplant surgery is currently the best way to treat uremia patients.
He originally thought that he would be able to live a normal life after the kidney transplant, but unfortunately his body suffered from serious rejection.
To put it simply, the immune cells in the body constantly attack the transplanted kidney, eventually causing problems with the transplanted kidney and forcing it to be surgically removed.
He knew that Dr. William said dialysis was the best way, but...
"Dr. William, I have been on dialysis for more than half a year. I am really fed up with this kind of life."
"When I was a normal person, I would watch an NBA game every week, swim and play basketball!"
"But now! The doctor told me not to drink too much water and not to eat too much. Too much, and I can’t do strenuous exercise!”
“My time is tied to the dialysis center and the dialysis machine. I haven’t been to a football game or traveled for more than half a year!”
“I even forgot what it feels like to urinate. I feel like I’m about to become a robot.”
William. The doctor fully understood Stephen's complaints, shrugged, then opened the drawer and took out a beautifully crafted promotional material.
"Professor Stephen, I introduced you last time. This is the 'Kidney Toxin Replacement Injection' from Huaxia Qingshan Pharmaceutical. You can try it. Not only can you feel the feeling of urinating again, but you can also Go to watch a football match, or even do a little exercise.”
Professor Stephen’s eyes fell on the promotional materials, and soon. Shaking his head:
“You introduced it to me last time, but the 60% toxin clearance rate will inevitably affect human organs, and I don’t want to take the risk.”
“And, I am Medicines from China are not trusted.”
“oh”
Dr. William spread his hands helplessly:
"Professor Stephen, I understand that you are biased against Huaxia Pharmaceuticals, because I was also biased against Huaxia Pharmaceuticals before, but... Qingshan Pharmaceuticals and other Huaxia Pharmaceuticals It’s not different.”
“By the way, I forgot to tell you, this drug is now in the second phase of clinical trials. Test,"
"Qingshan Pharmaceutical has improved the previous 60% effect to 70%! Compared with the 85% of the hemodialysis machine, it is only one step away."
"And, This is a medicine that can be removed instantly, and the toxins left in the body are not even as much as the dialysis machine!”
"70%!"
Professor Stephen's eyes were stunned, and his face was full of surprise. In just three months, has the effect improved by 10%? !
......
I stayed up late to update, I owe -1 chapter, and there is 1 chapter left. Currently there are 400 monthly tickets, 4 more tickets are added, and a total of 5 chapters are owed
(End of this chapter)