Chapter 142: Overseas pricing of kidney toxin clearing dialysis needle (please subscribe)
What Zhang Yang prepared was a two-pronged move.
First, find out as quickly as possible whether the combined use of BI's "Toxin Catalyst" and "Shendu Qing" has any effect. This is the most important thing for Zhang Yang and the most important part of this plan.
After all, the "BI-toxin catalyst" is already a ready-made semi-finished product, and it is most likely to be quickly applied clinically.
Second, Tsingshan Pharmaceutical has begun to develop a similar "macromolecule toxin decomposition catalyst", but this is only an alternative.
These two tasks are not strange tasks for Fang Hanliang. Even the first imitation of BI Company's "Toxin Catalyst" is not uncommon in the medical field.
In fact, in the field of pharmaceutical research and development, many pharmaceutical companies competing for the same target will imitate and study each other's drugs during the research and development process, thereby gaining some inspiration and competitors' research and development ideas.
More recently, Novartis was preparing to act as an agent for a "hepatocyte activator". After receiving samples from Qingshan Pharmaceutical, it first conducted component analysis in the laboratory to ensure a certain treatment. Apply for clinical trials only after the results are confirmed.
In short,
all drug patents are public. As long as the patented drugs are not publicly used for commercial activities, no one can secretly copy them to understand the effects of the drugs or use them to gain inspiration. I can manage it.
Of course, Tsingshan Pharmaceutical can also imitate drugs with similar effects through the crystal form patent of "BI-Toxin Catalyst", thereby gaining a deeper understanding of "Toxin Catalyst".
Fang Hanliang quickly clarified his next work tasks, but just as he was about to leave, Zhang Yang suddenly stopped him.
"By the way, Fang Bo, you were building a R&D team some time ago. Have you selected all the people?"
"Are there still people missing?"
Fang Hanliang stopped. Looking back:
"It's almost done, what's wrong?"
A smile appeared on Zhang Yang's face.
He thought of Zhou Xiaomei whom Ren Xiaomin mentioned before.
Last month he met Zhou Xiaomei several times at the drug research and development center, and it turned out to be exactly what Ren Xiaomin said.
Not only is her appearance much prettier than in high school, but her figure has also completely grown, becoming slim and curvy.
It was just that considering that Zhou Xiaomei had just graduated from college and was not yet able to take on the work of the R&D team, she was asked to work as a "handyman" in the drug R&D center. She would help any R&D team who needed help and get familiar with the basic work as soon as possible.
Seeing that a month or two has passed, we can arrange for Zhou Xiaomei to join Fang Bo's new team. She will start from the bottom "experimental assistant" in a serious and systematic way, and seriously study the entire process of drug development. process.
This will be of huge benefit to Zhou Xiaomei’s development and growth.
Thinking of this, he said:
"That's it, I want to introduce someone to your R&D team."
"She is a newly graduated undergraduate student with no work experience. Of course, you don't need to assign any key tasks to her. Just let her start from the lowest level as an 'experimental assistant'."
Fang Hanliang He was slightly startled.
To be honest, in the field of biopharmaceuticals, undergraduates cannot catch his eye.
But since Zhang Yang had spoken in person, he agreed after a little thought.
"Okay Mr. Zhang, what's your name? I'll go back and look at her information."
"Called..."
As soon as Zhang Yang said the words, he then thought:
"Forget it, I'll go to the R&D center with you. I haven't seen her for a long time."
"Okay."
The drug research and development center was about 150 meters away from the office building. Five minutes later, the two entered the door of the research and development center.
The R&D center has a total of four floors. There is a large conference room on the first floor. On both sides of the conference room are several medium-sized office areas of about 200 square meters, which are used for the office space of each project team.
Project team leaders like Fang Hanliang have their own independent offices, which are also located at the very back of the first floor.
The second and third floors are various large, medium and small laboratories, including about 20 basic chemistry laboratories, biology laboratories, animal laboratories, pharmacology laboratories, etc.
The top floor is where test supplies are stacked and some experimental data are stored.
Zhang Yang asked Fang Hanliang to go to the office first, and then he went to the second floor to look for Zhou Xiaomei.
After asking two colleagues along the way, I finally found Zhou Xiaomei who was cleaning experimental utensils in an empty "chemistry laboratory" on the second floor.
He was not surprised. What Zhou Xiaomei did was something that every "biology major" graduate had to experience.
Even he started out as an "experimental assistant", doing the most basic tasks of cleaning vessels, recording data, and cleaning the laboratory.
"Zhou Xiaomei."
The quiet laboratory was suddenly broken by a deep voice. Zhou Xiaomei turned her head, and when she saw clearly that the person calling her was Zhang Yang, her face was filled with surprise.
"Mr. Zhang?!"
Seeing that Zhou Xiaomei was a little flustered and even had nowhere to put her hands and feet, Zhang Yang couldn't help but smile.
He had met Zhou Xiaomei a few times in the past few days, but he only nodded from a distance. This was the first time he stood so close and chatted alone like today.
"You put the test tube away first and wash it when you come back later. You accompany me to the office first."
"Oh."
Although Zhou Xiaomei was surprised, she quickly turned her head, washed the test tube in her hand quickly, and then put it aside to dry.
"Okay, Mr. Zhang."
"Yeah."
The two walked out of the laboratory quickly. Looking at the familiar yet somewhat unfamiliar Zhou Xiaomei, Zhang Yang couldn't help but speak. Said:
“Little sister, it’s been almost two months since I came to the company, right? How is it going? Are you still used to it?”
"Well, I'm quite used to it." Zhou Xiaomei whispered.
Zhang Yang could feel that Zhou Xiaomei was a little afraid of him, but he did not say it out loud, and continued:
"That's good, I heard Brother Ren say before that you were preparing to take the master's degree exam. Are you ready? If you have any difficulties, you can come to me directly.”
“Well, thank you Mr. Zhang and Mr. Ren for your concern. I’m preparing. I’m fine at the moment. There’s no problem.”
"Okay."
Zhang Yang nodded slightly, looked at Zhou Xiaomei, and slowed down:
"I came to you today mainly because I have never arranged a job for you before."
"Now the company is setting up a The new research and development team on kidney drugs, I am going to recommend you to Fang Doctor, you can follow Dr. Fang to learn the research and development process comprehensively and systematically."
"This will be of great help to your future development."
Zhou Xiaomei's eyes. There was a flash of surprise, and of course she knew that Dr. Fang was forming a research and development team.
However, Dr. Fang has a very high vision. Not only does the R&D center only select seniors with sufficient R&D experience, but also external recruitment only requires industry backbones with more than ten years of experience in R&D of "kidney drugs."
She never thought that she would be able to join Dr. Fang's R&D team.
After a while, she looked up at Zhang Yang, then lowered her head and whispered:
"Thank you, Mr. Zhang."
Zhang Yang did not have Zhou Xiaomei Such delicate thoughts.
"Stop calling me Mr. Zhang all the time, just call me Zhang Yang."
As he said that, he also sighed:
"Unconsciously, you have graduated from high school and are working. "
"Speaking of which, I have watched you grow up..." Zhou Xiaomei lowered her head and listened quietly to Zhang Yang's words. Soon the two of them came to Fang Hanliang's office.
Zhang Yang did not write any ink and introduced:
"Fang Bo, this is the person I recommend to you. Her name is Zhou Xiaomei."
After saying that, he looked at Zhou Xiaomei:
< br>“Little sister, from now on you will be in Fang Bo’s team "Fang Bo is a well-known expert in the entire industry. You can learn a lot from him. Of course, I also told Fang Bo to let you learn from it." Experimental Assistant 'Start and study hard. ”
"Well, okay."
Zhou Xiaomei looked up at Fang Hanliang, her eyes no longer showing the shyness and embarrassment she had when facing Zhang Yang.
Although she was still a little nervous, she said generously and authentically:
"Dr. Fang, I will trouble you in the future. If you have any questions, please feel free to give me orders, and feel free to correct me if I do something wrong! ”
“Okay, okay, no trouble.”
After a brief introduction, Zhou Xiaomei was ready to leave.
She looked at Dr. Fang, and finally her eyes rested on Zhang Yang.
"Dr. Fang, Mr. Zhang, you guys chat, I'll go out first."
"Okay."
Zhou Xiaomei opened the office door and walked out, waiting for the door to open again When it closed, she finally let out a heavy breath.
Suddenly, the corners of her mouth couldn't help but raise happily, and her face was filled with a sweet smile, as if everything in front of her became so beautiful at this moment.
"Thank you, brother."
......
After arranging the imitation of BI's "Toxin Catalyst", Zhang Yang handed over everything to Fang Hanliang.
Fang Hanliang originally worked at BI Company. Although he did not participate in the research and development of "BI-Toxin Catalyst", he has more than ten years of work experience and knows some details and inside stories that outsiders do not know.
In addition, after Zhang Yang simply asked Lucas from GlaxoSmithKline to help get some samples of BI's "toxin catalyst" that was undergoing phase II clinical trials, the understanding of the "toxin catalyst" progressed extremely smoothly.
One month, two months,
While Fang Hanliang was collecting real data on the "toxin catalyst" at night, GlaxoSmithKline and Novartis were the first to send the news.
GlaxoSmithKline’s clinical trial of “Shenduqing” in India has been approved by the British regulatory authority and is allowed to be produced and marketed.
Novartis is basically the same. Although the progress is slower, it can also start to set the agency price of "Shenduqing".
Both Lucas and Friedman flew to Qingshan Pharmaceutical in person, and also brought the basic costs of dialysis in their respective countries.
The United Kingdom is an old capitalist country with a solid foundation. In 1948, before the empire of the sun never set completely declined, it launched a universal free medical system. This was also the first universal free medical system in the world.
According to data provided by Lucas, the annual cost of dialysis in the UK is approximately £25,000, which is equivalent to £175 per session.
These costs will be fully borne by the British NHS (medical insurance).
Zhang Yang positions the "Kidney Toxin Clearing Dialysis Needle" as a substitute for dialysis, so the price cannot be much higher than the cost of dialysis.
After discussing with Lucas, he decided to set the price in the UK at 192 pounds, which is 15% more expensive than the traditional dialysis mode.
Of course, considering that GlaxoSmithKline’s agents also need to make money, Qingshan Pharmaceutical’s agent shipping price is 135 pounds, equivalent to RMB 1,300 per shot.
As for the cost of dialysis in other parts of the EU, it is similar to that in the UK. The price in the entire EU is basically around 200-250 pounds per shot.
After taking care of Britain, the situation in the United States will be much more complicated.
The United States does not have universal free medical insurance. If you have insurance, such as participating in federal medical insurance, after deducting the deductible of US$150, the patient will pay 20% of the excess cost.
Of course, many patients have commercial insurance to cover this part of the cost.
For patients without insurance,
the cost of one dialysis session will reach US$400. If calculated as three times a week, twelve times a month, and 144 times a year, the annual cost for dialysis patients in the United States It will be close to $60,000.
The most terrifying thing is that if it is unplanned and emergency dialysis, the cost will be thousands of dollars!
"Zhang, you heard me right, just sell it at the price of 500 US dollars per injection. I am confident that we can get the 'Federal Medical Insurance' and 'Commercial Insurance' and let them dialyze our kidney poison Needle' covered by insurance! ”
"Don't worry, I will make it popular in the United States!"
Under Friedman's persuasion, Zhang Yang set the price in the United States at US$500 per shot, while the agent price for Novartis was US$300. One shot is equivalent to RMB 2,100.
After determining the selling price in their respective markets, the two immediately flew back to China to start publicity. At the same time, they also began to promote the inclusion of "Shenduqing" into their respective medical insurance systems.
After all, "Kidney Toxin Clearing Dialysis Injection" is not like other drugs. If it really wants to be promoted, it must be bound to medical insurance.
Just when GlaxoSmithKline and Novartis began to vigorously promote the upcoming launch of "Kenduqing" in the United Kingdom and the United States, the domestic medical insurance bureau also noticed that the "Kenduqing dialysis needle" passed clinical trials. information.
Beijing, China Medical Insurance Bureau Building.
A discussion on Tsingshan Pharmaceutical’s “Kidney Toxic Clearing Dialysis Needle” is coming to an end, and Liu Weiguo, director of the purchasing department, is making his final concluding remarks.
“Everyone has worked hard this afternoon, but the good news is that we finally discussed the minimum price of Qingshan Pharmaceutical’s ‘Kidney Toxin Clearing Dialysis Injection’.”
“I will not discuss the confidentiality regulations. I repeat, no one can divulge today’s discussion before completing negotiations with Qingshan Pharmaceutical, okay?”
“Understood”
"Okay, let's adjourn the meeting."
More than a dozen comrades participating in the discussion exhaled heavily.
Every time Tsingshan Pharmaceutical launches a new drug, the General Administration will discuss the price of the new drug included in medical insurance some time in advance.
There is no way, every time Qingshan Pharmaceutical’s new drugs have unparalleled therapeutic effects, they are urgently needed by patients.
It is too expensive and medical insurance cannot afford it. If it were cheaper, Qingshan Pharmaceutical would definitely not be willing to join the medical insurance, so this is a difficult job to do.
Fortunately, this time Qingshan Pharmaceutical's "Kidney Toxin Clearing Dialysis Injection" is not unique. At least there is a reference, so the discussion went smoothly.
Liu Weiguo also rubbed his temples and exhaled in his heart.
He returned to the office with the information, but before he could sit down, the office phone rang.
"Wei Guo, come to my office."
"Okay, Bureau Wei."
Liu Weiguo quickly put down the information and came to Wei Ming Bureau's office. He had vaguely guessed the reason why Bureau Wei was looking for him.
Sure enough.
"Wei Guo, I heard that you were discussing the medical insurance price of Qingshan Pharmaceutical's 'Kidney Toxin Clearing Dialysis Injection' this afternoon? Is the discussion over?"
Liu Weiguo nodded and reported to Director Wei Naturally, work is not a leak.
"Yes, Director Wei, we already have a preliminary psychological price. It depends on when Qingshan Pharmaceutical proposes to negotiate with us."
"Well, the result of your discussion...what is our psychological price?"
...
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(End of this chapter)