Chapter 169 Feng Gang: I was stabbed in vain!
The impact of "Strong Oral Liquid" is still fermenting on the Internet, but Zhang Yang has gradually withdrawn from the whirlpool of public opinion.
A few days later, he learned from Dean Zhou that Director Feng Gang and Director Feng had completed the pulmonary nodule surgery.
After thinking about it, Zhang Yang bought some fruits and flowers the next afternoon and went to the hospital in person to visit Feng Gang, who had just undergone surgery.
Respiratory Medicine Inpatient Department, Chenggong Third People's Hospital.
As a hospital employee and also a middle-level leader of the hospital, Feng Gang was placed in a double room ward with relatively good conditions. His wife, Sister Xu, was taking care of him.
"Sister-in-law, thank you for your hard work. I don't know what Director Feng can eat after the operation, so I just bought some fruit."
As soon as he entered the door, Zhang Yang put the fruit in his hand He handed it to Feng Gang's wife, Sister Xu.
"Mr. Zhang, you are so polite. We are very grateful if you come to see Feng Gang!"
"Sit down, please sit down quickly."
Sister Xu warmly greeted Zhang Yang to sit down, and Feng Gang, who was lying on the hospital bed next to him, was also quite moved.
"Zhang Yang, it's just a minor operation, you don't need to make it so grand... I will be discharged from the hospital in two days!"
Zhang Yang smiled and said nothing.
What Feng Gang said is true. Nowadays, medicine has become more and more advanced. Ten years ago, a pulmonary nodule operation still required a thoracotomy.
But now most pulmonary nodule surgeries only need to find the location of the pulmonary nodules through CT-guided positioning and three-dimensional virtual positioning before surgery, and then use minimally invasive surgery.
Apart from anything else, at least the patient's trauma is much less, and they can usually be discharged from the hospital in three to five days without complications.
"It's okay, Director, I have nothing to do this afternoon... I just stopped by to see you."
"Well, thank you, Zhang Yang."
The two chatted. After a few words, the topic gradually shifted to Feng Gang’s ground glass nodule.
"By the way, director, have your pathology results come out? Have you finally confirmed that it is carcinoma in situ?"
It's okay not to say this. When he heard this, Feng Gang's expression suddenly changed slightly, and a trace of helplessness flashed in his eyes:
"The major pathology results haven't come out yet, but..."
"The pathological examination during the operation showed that my ground glass nodule was not carcinoma in situ, but a benign hyperplasia."
"Huh?!"
Zhang Yang was also stunned.
When performing tumor surgery, doctors will immediately send the cut "pulmonary nodules" and other suspected tumor tissues to the laboratory for "slice testing" during the operation.
The purpose is to get the best results Quickly know the type of tumor and the stage of cancer it has reached, allowing the surgeon to promptly determine whether to expand the scope of surgical resection.
Of course,
Due to the very tight time limit, intraoperative pathology may not be able to fully evaluate the "tumor tissue" and can only determine a rough estimate;
So in addition to intraoperative pathology Detection, there is also a most accurate major pathology.
Major pathology results are generally available 5-7 days after surgery, and this result is the absolute gold standard.
But...
Intraoperative pathology tests like Feng Gang’s showed benign hyperplasia, and 99% of major pathologies are also benign!
Thinking of this, Zhang Yang was shocked!
If the pulmonary nodules are benign hyperplasia, then there is no need for Director Feng to perform surgery at all!
In other words...
Feng Gang was stabbed in vain!
"Director Feng, how could such an oolong happen? Didn't you see a doctor before the operation? Why did it turn out to be benign hyperplasia?"
Feng Gang couldn't help but sigh. :
“Not only did I see a doctor, but I also specifically saw Director Liu and Deputy Director Zhang from the Department of Respiratory Medicine in our hospital.”
"Do you remember that my surgery was postponed for a few days? At that time, it was because the two directors had differences. Director Liu thought it was carcinoma in situ, and Deputy Director Zhang thought it might be benign hyperplasia. I thought about it for several days and decided to have the surgery! ”
“After all, my ground glass nodule was already 8mm at that time. If left unchecked, it would probably develop from carcinoma in situ to 'microinvasive adenocarcinoma', which would be troublesome."
"I didn't expect that it would turn out to be a benign hyperplasia."
Zhang Yang. He didn't expect that there was such a story behind Feng Gang's surgery, but he soon felt like he had seen it before.
When Ren Xiaomin was asked to screen for pulmonary nodules among employees of Tsingshan Pharmaceutical, didn’t there also appear to be such divergent cases among several colleagues?
It seems that the judgment of benign and malignant pulmonary nodules is just as Ren Xiaomin said at the beginning, there are many misdiagnoses.
Zhang Yang couldn't help but feel a little helpless for Feng Gang's experience, but he could also completely understand Feng Gang's choice.
The pathology of lung cancer is roughly divided into three stages:
The first stage is carcinoma in situ.
To put it simply, a malignant tumor suddenly grows on the lung tissue, but the tumor is still very small at this time and has not yet broken through the basement membrane and entered the lung tissue.
The solution is also very simple. Just surgically cut off the tissue around the lung nodule, and the treatment effect can be 100% cured.
This is early stage lung cancer, stage 0.
The second stage is: minimally invasive adenocarcinoma.
Literally means "micro-infiltration". At this time, the cancer cells have broken through the basement membrane and entered the lung tissue, but the scope of diffusion is not large, only within a few mm of tissue surrounding the malignant tumor.
Micro-invasive adenocarcinoma requires larger lung tissue removal than carcinoma in situ, but this is still early-stage lung cancer, stage 1 or 2.
The third stage is invasive adenocarcinoma.
As the name suggests, it has begun to invade the lung tissue, and with the invasion, it is also accompanied by lymph node metastasis.
At this stage, the prognosis is relatively poor, and surgical resection is no longer curable. The metastasis of cancer cells requires chemotherapy, radiotherapy, targeted drugs and other methods to extend life span.
So, the earlier lung cancer is discovered and the more attention is paid to it, the less threatening it is.
At this moment, Feng Gang interrupted Zhang Yang’s thoughts and continued:
"This man, when I was worried that it was carcinoma in situ, I kept thinking about having it removed quickly to prevent it from metastasizing."
"But now after the surgical removal, it was found to be a benign hyperplasia and I regretted it. I want to show you I don’t know, this time my lung nodule is very deep in the lower lobe of the left lung, so a lot of lung tissue must have been cut.”
“The lung tissue can’t be regenerated, so it was cut. Some will definitely affect lung function, and now I’m starting to worry about my lung function again..."
"Many people don’t know, but I know very well that postoperative symptoms such as coughing, chest tightness, and suffocation are very likely to occur. , even taking two steps up the stairs makes me breathless.”
At this point, Feng Gang suddenly coughed several times and couldn’t help but sigh:
"Hey, Zhang Yang, do you still remember what I said to you before?"
"At the beginning, I also suggested that you develop a targeted drug to treat pulmonary nodules. Now it seems that it is still It is better to develop a drug that can identify whether pulmonary nodules are benign or malignant, so as to reduce the number of unnecessary surgeries!"
Zhang Yang couldn't help but smile. Ren Xiaomin seems to have mentioned this request once before, but it's not that simple!
But he still said comfortingly:
"Okay, okay, director, your suggestion is very good. I have written it down. When I get back to the company, I will discuss the feasibility with the R&D team."
Of course Feng Gang is not naive enough to think that this matter has been settled. The two then discussed work matters for a while. After about fifteen minutes, Zhang Yang felt that the time was almost up, so he stood up and left.
Feng Gang's wife, Sister Xu, personally sent Zhang Yang downstairs. As he was on his way back to the company, Zhang Yang started to think about the suggestion Feng just mentioned in his mind while driving.
First of all, from a commercial perspective, the market prospect of developing a drug that can identify whether pulmonary nodules are benign or malignant is bound to be broad.
If nothing else, who the hell wants to get stabbed without any certainty?
Just like Feng Gang, if it could be judged that it was benign hyperplasia before surgery, surgery would not be necessary at all. Not only would the money be at a loss, but so would the people.
“But what method should be used to distinguish whether the nodules on the lungs are benign or malignant?”
“Take medicine?”
“Medicine can do the trick. Rapidly reaching lung tissue, malignant tumors also have some 'tumor markers' that are different from benign tumors , but in the end, even if the drug recognizes these 'tumor markers', how should they manifest themselves? "
"Moreover, many patients have more than one lung nodule. How to clearly judge one or several lungs? Are the nodules benign and the others malignant? ”
"In other words, the 'tumor marker' method does not work, and it is impossible to accurately determine which pulmonary nodules are problematic!"
Zhang Yang thought about it while driving, but the more he thought about it, the more he felt that this matter was fundamental. It's not something that one drug can solve.
In other words, there is no way to solve this problem with current medical technology!
Twenty minutes later, he returned to Qingshan Pharmaceutical and immediately called Wei Tian and a group of technical backbones for a meeting to discuss the feasibility of this matter.
After some discussion, everyone basically agreed. With the current development of medicine, it is almost impossible to distinguish between benign and malignant pulmonary nodules by relying on one drug alone.
In desperation, Zhang Yang had to give up the idea temporarily.
In the next few days, he returned the focus of his work to the clinical trials of "Qiangjing Oral Liquid".
With the influence of the proposal, the clinical trial of "Qiangjing Oral Liquid" is going smoothly, and some people in the group are even starting to queue up for the third phase of clinical trials.
Zhang Yang finally felt relieved.
Looking at the weekend, he even rarely asked his little sister last week to watch a movie and have hot pot together. When he returned home with a bulging belly, he suddenly found an exciting voice coming from his mind. .
"Dear host, the new simulation plot node has been activated. Please enter the simulator as soon as possible to check it out!"
Zhang Yang's eyes lit up and he quickly entered the simulator!
You know, the simulation story mode in the simulator has not been activated for more than a year!
The most important thing is that although the simulator has been updated to version 2.0 with more powerful functions, all functions of version 2.0 require energy!
In the plot mode, you can not only get the top drug patents provided by the system for free, but you can also earn a lot of energy!
Entering the simulator excitedly, he called out the light blue light screen, and saw an eye-catching task prompt displayed on the light screen:
[Current simulation node: Phase 1 - Biological Laboratory. 】
As a veteran who has experienced many simulation plots, Zhang Yang entered the simulation plot directly without any hesitation!
【Start simulation! 】
After a period of darkness, the scene gradually became brighter. With the experience of several previous simulations, Zhang Yang did not move for the first time, but took the lead in looking around to determine where he was.
Soon, the familiar scene in front of him surprised him.
Several experimenters wearing white lab coats (white coats) are busy working with various test tubes and reagents on the operating table, while two others are recording on the computer.
The familiar white lab coat, the familiar biological operating table, the familiar test tubes and instruments!
Here it is!
A biological laboratory!
And I...
Seems to be a biological researcher?
"Could it be that this time the model is to develop a drug as a biological researcher?"
Zhang Yang's imagination suddenly opened up, but after several simulation experiences, he did not Anxious to make sure, he continued to observe the situation in the laboratory, and soon noticed some differences.
Same as in the last copy of "The Destiny of a Generation", there are about four or five people in the biology laboratory, and these experimenters are all foreigners!
"Is this a foreign biological laboratory?"
Two huge questions emerged in Zhang Yang's mind. What he needs to do now is to first determine his identity and where this is!
After looking around, he immediately walked to the nearest white experimenter who was taking notes.
"Hi, man, I have lost my memory. Where is this place? What time is it now? What are we doing?!"
The white experimenter was stunned for a moment, then turned back and rolled his eyes at Zhang Yang .
"Mr. Zhang, I know you are usually very humorous, but I don't think this is funny at all;
Don't think that you don't have to work because you are pretending to have amnesia. Let me tell you, you will definitely have to work before you finish your work today. "Be left behind."
Zhang Yang knew this was a simulated plot and was too lazy to do so. He couldn't be more verbose, and suddenly grabbed the collar of the white man in front of him, and said with a fierce expression: "Fuck, I'm not kidding you! Tell me what time it is, where we are here, and what we are doing!" "
" Damn it! "
Zhang Yang's loud voice caused several experimenters present to look over, and the white man who was caught couldn't help but spit out the fragrance.
However, under Zhang Yang's strong coercion, he quickly replied:
"Zhang, I think you have not lost your memory, you are crazy!"
"Today It’s August 9, 2018. This is Adlev Biolab in Norway, and we are all assistants to Dr. Eric!”
“We are currently conducting data analysis on small cell lung cancer in lung cancer. ! ”
"You are responsible for collecting and summarizing the disease data of the Nordic population, and I am responsible for collecting and summarizing the disease data of the Asian race!"
"Do you have any more questions?"
< br>Collecting racial prevalence data for small cell lung cancer?
Zhang Yang was slightly startled, there was indeed such collection work in the biology laboratory.
After a moment, he let go of the white experimenter in his hand, with a smile on his face.
"Okay, last question, what's your name?"
"Evans."
(End of this chapter)