Chapter 453: Give him an injection
“Okay, let’s talk about the business.”
Frederick stood up with a smirk, licked his lips, and slowly walked towards Maria .
Maria blushed and glared at him, and just as she was about to kick him over, there was a heavy knock on the office door.
"I won't disturb you anymore!" Maria immediately stood up, straightened her hair and clothes in front of the mirror behind the door, and then opened the door and went out.
Outside the door was Christian, the Minister of Foreign Affairs. He had no intention of entering. He handed a red-covered letter to Maria and said, "I will leave right away. I am just here to deliver an urgent message from the Kingdom of Gaul."
Maria Leah glared at him hard and said expressionlessly: "My business is done, you can go in."
Christian was surprised: "So fast?!"
Frederick in the office said with a black line: "If you keep talking nonsense, I will let you go on a business trip to the forest south of the inland sea!"
Christian's face immediately changed and he looked serious.
Weissenburg University has a branch in the south. Many people went there to teach out of curiosity, but most of them couldn't stand it and ran back.
Frederick took the letter and asked: "The Kingdom of Gaul has begun to attack?"
Now the Kingdom of Gaul continues to gather troops in the south, domestic food prices have risen, and the wheat harvested in the summer will not only repay the friendship There is no export outside the bond part, and everyone knows that it will start after the summer harvest.
Christian replied: "His Majesty Old Louis has been in poor health since he was injured last year. Now he is diagnosed with sepsis and is dying."
"His Majesty Little Louis wrote a letter asking us if we have any Methods of treatment.”
Frederick took out the letter and read it. Old Louis was injured in a competition in November last year and his wound was seriously infected. He later contracted septicemia. He relied on natural materials and treasures to hang himself until now, and it seemed that he could not hang anymore.
Christian continued: "According to the information we have learned, His Majesty Old Louis held that knightly contest in order to show his prowess in front of women."
Frederick was speechless. .
Septicemia is an ancient disease that has recently been re-recognized. It was once considered a curse like other incurable diseases. Frederick was able to determine that bacteria had infected the blood after taking out bacterial cultures and microscopy.
Now the disease can only be treated with herbs and hard work. Little Louis has no hope. The letter said that it can be cured no matter how much it costs, but it cannot be ignored.
Frederick had nothing to do about this. Antibiotics such as penicillin were still far away, and the only one available at present was allicin.
"The only thing we can do is try that one." He stood up, "Maybe we will make history again."
Christian's eyes lit up, and he became excited.
Frederick moved people very quickly, and after two hours the heads of several departments gathered in the office.
Medical Minister Frank read Little Louis’ letter and briefly told everyone about Old Louis’ condition.
"The poisoner who is not doing his job" Friedrich has made a lot of money by saving people with medicine in recent years. He has three gold necklaces and a gauze mask hanging around his neck at the same time. After listening, he frowned and said: " The treatment of sepsis is very troublesome. The most recent case was a soldier in the Wesson Army. He relied on taking a lot of allicin and being in good health. It took three months."
Frank also said: "The cases in the hospital are similar, and the treatment time is long. We are betting on whether the patient's life or the recovery time will be longer."
One of the advantages of the government of the Principality of Wesson is that experts govern the country. When it comes to technical issues, officials can take a professional perspective Look at the problem.
If we were to replace officials in other places, many of them would make decisions based on patting their heads.
Frederick stood in front of the blackboard and said: "I have an idea to try. Inject allicin into the blood to directly kill the bacteria in the blood."
Many people present thought it was impossible, but Frederick had too many glorious precedents to object to.
Frederich said: "You can try this method."
"Some poisons act through the blood and work quickly."
"But There is a problem. This kind of poison can often be eaten. If there are no wounds in the mouth and stomach, it will not be poisoned. If you see blood, it will kill you."
His meaning is very clear. There is no problem in eating allicin, but. It is not necessarily a problem whether there is a problem with the injection into the blood vessel.
Frederick said: "Let's try it on pigs first."
After he finished speaking, he began to draw needles, syringes, infusion lines and other injection items on the blackboard, and explained how to inject IV drips. Frank said: "There are needles in hospitals now, which are mainly used to drain pus, fluid and remove cataracts."
Frederick didn't know much about these. In fact, needles have a long history. In the past, sharpened quills were even used as needles.
Omet was wondering at first what he should do to cure the disease, but now he understands that he must organize the production of these things.
Although I am no longer the Minister of Industry, I am very familiar with the factory and know who can do what. I just go to them directly.
He said: "These instruments are not difficult to process. They can be cleaned and disinfected after processing. I can arrange for people to do it."
Frederick once again felt that there was an industry in the territory The system is really good, and he reminded: "The materials used must be acid and alkali resistant. At least they will not be damaged when placed in a pressure cooker for high-temperature sterilization."
"At the same time, there must be a volume scale on the syringe, which can be used as a measuring cylinder. .”
Omet immediately wrote it down in his notebook.
At this time Friedrich raised a new question: "Principal, there is a question about blood."
"I have observed it under a microscope. The red blood cells in the blood will absorb water, grow in size and eventually burst in distilled water. "
Frederick nodded and said: "This problem is the biggest problem that plagues artificial insemination, and it can be solved now."
"Use the purest salt and distilled water to prepare 0.9%. Saline is used to dilute the allicin and then inject it into the blood vessels."
After writing it down in his notebook, Friedrich said, "I'll try it first."
In the professional field, he didn't believe it immediately just because it was Frederick who said it. He had to do experiments.
Frederick said: "These drugs are to be injected into the blood vessels and must be kept pure and sterile so as not to introduce new pathogens into the blood."
Frederich After thinking for a while, he said: "That's no problem. The allicin and salt water can be filtered through multiple talc powder and activated carbon, and finally the solid impurities are removed through filter paper and a centrifuge. Finally, Manuai is caught and sterilized."
Frederick was used to them capturing Manuel, the vice-president of Weissenburg University and the world-famous necromancy magician, to use as a disinfectant.
He thought for a while and said: "I think it would be better to prepare a sterile place for processing."
He didn't expect to have a sterile laboratory like his hometown, just try to keep it as clean as possible.
Frederick immediately said: "I have such a laboratory there, which is used to prepare some perishable medicines."
After his explanation, Frederick understood. There is a type of medicinal berry whose skin cracks when ripe, and the juice is easily fermented, using the smell of wine to attract specific animals to eat. This requires processing in a laboratory where there are no natural yeasts in the air.
Frederick couldn't figure out what was going on with those berries, it would be great if there was such a laboratory.
The task was quickly arranged. After everyone left, Frederick leaned on the chair and took a deep breath.
He doesn’t know whether injecting allicin can quickly cure septicemia, or whether the patient will be allergic, but once the cure is extremely profitable, it will be a dead horse.
At least order the infusion. In the future, infusion of normal saline can also treat dehydration and massive blood loss caused by diarrhea, which is not bad.
Then he thought about glucose.
Frederick remembers that when consuming glucose, it is like boiling starch paste with sulfuric acid for about four hours to hydrolyze it, until it does not change color when dripping iodine and there is no white precipitate when dripping anhydrous alcohol. After the first filter, add lime milk. To remove sulfuric acid, carbon dioxide gas can be passed through to remove excess lime milk. After the second filtration, activated carbon is added repeatedly to decolorize and filter until the sugar solution is clear, and finally the sugar is crystallized.
The biggest problem in making injection-grade glucose is filtration. Proteins, heavy metals and other components in plant starch raw materials can precipitate at different pH levels. It may be acidified and hydrolyzed with hydrochloric acid, and gradually neutralized with sodium carbonate. The effect is better.
Frederick tried his best to recall the contents of making glucose, then wrote it down on a piece of paper, and then named it "Sugar of Life" for Frederick and others to study slowly.
The fastest mover was Friedrich. His laboratory was next to Weisenberg University. As soon as he returned to the laboratory, he immediately prepared different concentrations from 0.7 to 1.2% according to Friedrich's instructions. saline and observe the effect on the blood under a microscope.
At the same time, he arranged for his men to prepare piglets and wait for the syringes to come to test the side effects and lethal dose of allicin injection.
Then a problem arises: Allicin is difficult to dissolve in water.
(End of this chapter)