Chapter 154 The experiment was successful!
The autistic man was making love to the girl in the yellow down jacket under the big tree.
The three bad friends were stunned not far behind!
"Damn, I read that right, they are holding hands! They are holding hands!"
"Is this a relationship? Chen Ming is autistic! Autistic Are you in love?”
"He's just autistic, and it's not that he doesn't like girls, so why can't he fall in love!"
"No, he's autistic, so he has to have some love when he's in love! When a girl talks to him, he Look at the ceiling, what kind of love is this?"
"Is it possible that that woman is just Brother Shiran's half-sister?"
"That's what you said, come to Qingdao University? Is it to find a female classmate to be your boss?”
“If a girl wants to fall in love with Brother Haotian, it’s because he’s sunny and handsome; if she’s looking for Viagra, it’s because you have academic achievements and can write novels. ;If you come to me, it can be said that I have money.
Looking for Brother Ben to fall in love, what are you trying to do? Brother Specimen looks thin and small, and is far inferior to Brother Haotian in terms of appearance. In terms of ability, although he can enter the laboratory, he is far inferior to Viagra. And he has no money!
The conditions of the three of us are better than Brother Specimens by any calculation. Why, it was Brother Specimens who found a girlfriend first and fell in love, and the three of us were still single! Who can I ask to explain this? "The pretender looked unbalanced.
"You two are single, so don't get involved with me. I do have a girl who likes me. "Ye Haotian said immediately.
Zhang Weishen nodded in agreement: "That's right. Let's not talk about the female Bodhisattvas in the school who want to eat Tang Monk's meat. Look at Xiong Xinxin, she chased Ye Haotian to the Qing Dynasty. Big is coming. So if you want to say that you are single, your brother Haotian definitely doesn’t count, and of course, neither do I! "
"What? Viagra? Are you also in love? "The pretender showed a surprised expression.
"No, although no girls like me, there are professors who like me! Several department heads in our school are eager to recruit me as their son-in-law!
I can at least get a class here. My father-in-law is chasing me! If you have a father-in-law, you also have a girlfriend in your class! So strictly speaking, you are the only one who is truly single." Zhang Wei said with a smile.
“It can still be calculated like this!” The pretender looked unconvinced, and then said: “If that’s the case, I still have money! If I have money, I can find a lot of girlfriends! I'm not single!"
Zhang Wei patted the pretender on the shoulder and said earnestly: "Xiao Lu, I kindly remind you that it is illegal to spend money on this kind of thing! Let’s talk about love!”
“Brother, you are double standard! You recognize your father-in-law everywhere and you don’t even ask if your daughter agrees. How can you talk about love?”
"The parents order the matchmaker to respect the tradition! How dare you not ask your parents for their opinions when you marry a wife in the future?" Zhang Wei explained with a smile.
"What about Brother Haotian! He relies on his good looks to attract bees and butterflies. He is betraying his appearance!"
"Xiao Lu, there is a problem with your idea. , It’s someone else who wants my body, I’m completely passive, how can this be considered betraying my lust?” Ye Haotian said immediately.
“I understand, the richer you are, the more vulnerable you are!” the pretender grunted.
……
In the dormitory, the three-chamber trial began!
The autistic man sat in the middle of the dormitory with an innocent expression like a little white rabbit.
"Don't pretend to be pitiful. Who is that female classmate in the yellow down jacket? Hurry up and recruit her!" Zhang Wei snorted coldly.
"Her name is Xin Xiaoxuan." The autistic person answered.
"Which department? How old are you?"
"Law department, freshman."
"Beasts, even freshman girls can kill them!" Ye Haotian snorted coldly.
"Stand aside, Xiong Xinxin is also a freshman, you have no say in this aspect!" Zhang Wei said.
"It sounds like you have the right to speak!" Ye Haotian curled his lips.
"I definitely have the right to speak. Don't forget, I'm also a freshman." Zhang Wei said proudly.
"You repeater!" Ye Haotian sneered, and then went on to interrogate Chen Ming: "How did you two adulterers and adulterers get together? Hurry up and tell the truth. If you resist, you will be lenient, but if you confess, you will be stern!"
The autistic man was stunned, wondering if I should resist, but he still answered: "We have a common hobby!"
"She also likes quantum physics?" Zhang Wei was surprised asked.
“She also likes to drink beer!” the autistic man replied.
“According to this standard, at night these food stalls in Zhongguancun will be filled with your girlfriends!” Zhang Wei said with a smile.
Ye Haotian asked: "How did you and Xin Xiaoxuan meet?"
"One day, after doing the experiment, I ran behind the tree to drink beer secretly. She saw it and asked me for it, and we Got it." The autistic man replied.
"I also know that to pick up girls, you have to invite her to drink! Brother specimen, you can do it!" Lu Yunxiang said.
“She asked for it from me, but I didn’t give it to her!” the autistic person added.
"All the girls want it from you! You don't give it to me! Is this playing hard to get? Brother specimen, I don't see it. You have some tricks to chase girls!" Lu Yunxiang said.
"Xiao Lu, you are overthinking. This guy is just stingy." Zhang Wei continued to interrogate: "What happened later, how did you get together?"
"She invited me to drink beer." The autistic man spoke.
“A typical woman with breasts is a mother!” Ye Haotian said.
The autistic man shook his head decisively and said categorically: "This is a common hobby! We got together because of our common hobby!" "You are sure, it's not because you are greedy or greedy for other girls. Beer?" Ye Haotian asked with a smile.
"No! Later I also invited her to drink beer!" the autistic man said.
“No wonder the beer I gave you was half missing the next day. It was all given to Xin Xiaoxuan, right?” Ye Haotian showed a crime-solving expression, and then joked: “Since you are not a greedy person, He must be greedy for his beer.”
This time, the autistic man didn’t answer, but his expression seemed to acquiesce.
The remaining three people showed surprised expressions at the same time.
“Here, brother Haotian, did you see that Chen Ming is starting to be interested in girls’ bodies!”
"Could it be that Asperger's syndrome can be cured by finding a wife?"
"Brothers, aren't you worried? With Brother Ben's brain circuitry, will he spend money? To satisfy your own interests? That’s illegal!”
“Xiao Lu, I think as long as you don’t remind me, you shouldn’t think that you can still spend money on this kind of thing!”
"It's okay. Your brother specimen is poor and stingy. If you ask him to spend money to solve the problem, he can't afford it." Ye Haotian said.
"Brother Haotian? How do you know the price? Have you spent money to find it?" The pretender's mouth became more and more derogatory.
"Have you never eaten pork? Haven't you ever seen a pig running? My house is next door to Dongguan!" Ye Haotian said.
Zhang Wei then said: "Xiao Lu, for the sake of safety, if your brother Zijin borrows money from you in the future, it is better not to borrow money from you! In case he makes a mistake."
"Brother. "Don't worry, don't talk about Brother Shen. If you two ask me to borrow money, I won't borrow it!" he said in a cowardly manner.
……
A new round of experiments, the results are finally out.
Liu Xuetai took the experimental results and reported: "The first set of pseudouracil modification experiments, five experimental samples, the immune system works normally!
The second set of pseudouracil modification experiments, five experiments In three of the samples, the immune system was functioning normally! In the other two samples, the nucleoside-modified mRNA successfully entered the target cells. "It was finally successful!" Zhang Wei suddenly became excited when he heard the result. .
Even if only one sample of nucleoside-modified mRNA can enter the target cell, it means that Zhang Wei's experiment has been successful!
Now two experimental samples have been successful, which directly proves the repeatability of this experiment.
So Zhang Wei immediately asked: "The second set of experiments is a quarter of the original dose, right?"
"It's a quarter." Liu Xuetai nodded.
“According to a quarter of the drug dose, two of the five experimental samples were successful, which means that if the drug dose is reduced, the probability of success will be greater!”
Thought Here, Zhang Wei immediately asked: "The third group should be one-eighth of the dose, right? How is the situation?"
"The third group of pseudouracil modification experiments, five experimental samples, Only one immune system worked normally! In the other four samples, the nucleoside-modified mRNA successfully entered the target cells.”
"Give me the lab report!" Zhang Wei couldn't wait to take the lab report and confirm the results again.
The mRNA modified with nucleosides is all labeled with fluorescent dyes. If it enters the target cell, the result will be clear at a glance.
“Have all the experimental records been saved?” Zhang Wei then asked.
"Saved." Liu Xuetai nodded.
"That's good!" Zhang Wei hesitated for a moment, still feeling a little uneasy, so he continued: "Repeat the experiment again according to the dosage of the third set of experiments! Remember to videotape the entire experiment! ”
"Okay." Liu Xuetai nodded, and then went to work.
Obviously, he, who was still in his second year as a graduate student, did not realize that they had already made a major achievement.
Zhang Wei was happy. With the experimental data, he could publish a paper directly!
Zhang Wei was not surprised by Liu Xuetai's cold behavior.
At that time, the research results of nucleoside-modified mRNA, let alone a few graduate students, even many top professors in biology departments could not see any great significance.
Historically, this result was first published in the journal "Immunology", and after the results were published, there was no enthusiasm at all.
The two Nobel Prize-winning experts who studied this project later published several articles related to it, but still no one paid attention to it.
Mainly because, according to the understanding of the academic circles at that time, there was still a huge distance between this technology and its practical application. Humans can synthesize and edit mRNA at will, and then produce the desired proteins to overcome most diseases. It may take hundreds or even hundreds of years to achieve this.
Who will pay attention to a research that will only be applicable hundreds of years later?
This is like measuring the thrust vector of a rocket engine in Newton's time. What's the use?
However, the two Nobel Prize-winning experts who researched this result are also really convinced, and they may have really run out of funds. They can't wait to commercialize this technology, and even established a company in 2006. , selling patents in this area and seeking financing.
The result was that the patent could not be sold and there was no financing, and the company quickly went bankrupt!
This is the basic core technology for developing mRNA vaccines!
More than ten years later, this technology has made all vaccine companies salivate, and it has even created a vaccine giant with a market value of 100 billion!
Do you dare to imagine that in 2006, this kind of technology, which can bring huge economic benefits, was completely ignored, and the company that sold this technology even went bankrupt!
(End of this chapter)