Chapter 700 Three-dimensional skin graft forming technology
On the first day after surgery, Yang Ping led everyone in the general surgical ward for ward rounds.
Teacher Sun's entire body was wrapped in bandages except for his eyes and mouth. Of course, the excretory terminal was also wrapped.
Moreover, these bandages do not need to be replaced and remain wrapped for 12 days before being removed. Within 12 days, Teacher Sun could only urinate through a urinary tube; defecate on the bed and rely on a bedpan; eat by feeding, and if necessary, a gastric tube may be used to grind and pulp the food into a semi-liquid form, which can be passed directly from the stomach. The tube is injected into the stomach. In short, eating, drinking, and diarrhea can only be done in bed. This is the so-called "absolute bed rest."
Absolute bed rest means lying in bed every second. Even if you get out of bed once, it is not considered absolute bed rest.
It takes 10-12 days for the transplanted skin graft to establish a blood supply relationship with the base. Within 10-12 days, pressure is needed to maintain the nutritional supply of the skin graft. After 10-12 days, new blood vessels between the base and the skin graft are established. Even if The skin graft can still survive without external pressure, so the pressure dressing can be removed at this time.
After these 12 days, Teacher Sun can emerge from the cocoon and become a butterfly.
In the ward, Teacher Sun's students are very enthusiastic. They take turns taking care of Teacher Sun, feeding her porridge and water, carrying feces and urine, and sharing their studies or work stories with Teacher Sun in their spare time.
"Teacher Sun, how are you? Does it hurt?" Yang Ping asked with concern.
Teacher Sun could only move his lips in a small range, and said a little vaguely: "I was peeled off a layer of skin, why didn't I feel any pain?"
Unexpectedly, Teacher Sun was quite humorous with this metaphorical image of being peeled off, and his words caused a burst of laughter.
"Didn't you see that we are a pain-free ward with a sign on the wall? If you cry out in pain, wouldn't you smash our sign?" Yang Ping joked along with his words.
Teacher Sun immediately said: "Is the matter so serious? In this case, even if it hurts, I will bear it. I will not ask the doctors and nurses to give painkillers. I will never do anything to damage your brand."
The teacher's eloquence is so good that he can still joke with the doctor after turning into a mummy.
"You are wrong again. If you are in pain and ask the nurse to give you an analgesic injection, it means that our analgesic plan has failed. An excellent analgesic plan is not to give drugs on demand, but to give drugs at regular intervals. It does not require you to be in pain before giving painkillers. Instead, administer the medicine in advance to prevent you from experiencing pain." Yang Ping took the opportunity to educate him on the concept of pain relief.
Regarding pain, we didn’t pay much attention to it before, but now we attach great importance to it. Body temperature, heart rate, pulse, and respiratory rate are the four major vital signs. Pain is now listed as the fifth major vital sign.
Therefore, many places now promote pain-free wards and implement new analgesic concepts and plans. However, most pain-free wards still pretend to be fake and do not really do the job. This is the same as the packaging advertisement of beef noodles. The pictures are only for reference.
"Thank you all, thank you Professor Yang, thank you Dr. Ivan!" Teacher Sun said gratefully.
He was lying on the bed, feeling very excited. He hoped that these 12 days would pass quickly. He wanted to see his whole body changed, his new self.
Teacher Sun knew that if it weren't for Yang Ping's reputation, how could this world-class plastic surgery master have performed an operation on himself? I heard that he charges millions of dollars for one operation.
"You have a good rest. Dr. Ivan will change your scalp, transplant hair, do double eyelids, and transplant eyelashes for your next operation. I want to ask you now. Regarding your hair, you can choose - thick, sparse, bald. , or other desired hairstyles? ”
"Can the hairstyle be customized?"
“It’s considered custom-made.”
"There's no need to pick, it's just dense. You're welcome even if it comes."
"Okay! We have already helped you grow a scalp with hair and eyelid skin with eyelashes in the laboratory. They will be almost ready for use when you have surgery."
After chatting with Teacher Sun for a while, and after checking the room, Yang Ping and everyone went to the laboratory to see the new skin graft cultivation in progress.
When Teacher Sun performed the skin grafting operation, he had already removed some remaining hair follicles from his head. These precious hair follicles were saved like seeds and then implanted into the skin graft in the laboratory. Skin grafts are expanded and eyelashes are cultured using the same method.
If Teacher Sun's surgery was not supported by in vitro skin amplification technology, it would be impossible to obtain so many skin sources, nor would it be possible to obtain such high-quality skin sources, let alone obtain skin grafts with hair.
After checking the room, everyone came to the laboratory again.
Fatty Liang was helping out in the laboratory as Tang Shun's assistant, just doing odd jobs.
Tang Shun was doing it himself, putting a small piece of skin into the incubator. When he saw Yang Ping and everyone coming in, he immediately ended what he was doing. "How is it?" Yang Ping asked him.
Tang Shun nodded with satisfaction: "I implanted hair follicles into skin grafts according to the experimental plan. Nine hair follicles were implanted at a time. The spacing is very close. According to our technology, it can be replicated according to the density I have prefabricated."
With this first experience, Tang Shun now has no doubt that the experiment will be successful.
"With this new doubling technology, is the expanded skin a continuous copy of the raw material? It has no hair, and the expanded large-area skin graft has no hair either; if it has hair or hair follicles, the expanded skin also has no hair. Will it have hair or hair follicles and be of the same density as the source skin?" Ivan asked after listening to their conversation.
Tang Shun answered with certainty: "Yes, that's it, magical, right? This principle is completely different from Professor Mannstein's technology. To be precise, he is amplifying, and we are doubling."
Ivan took a deep breath and thought about the word "copy" repeatedly in his mind.
This is true replication, and this technology is very innovative.
"So, as long as there is one hair follicle, you can copy a hair follicle?" Ivan broke the casserole and asked.
Tang Shun knew that Yang Ping had no hidden intentions, so he told the truth: "Correct."
"How do you control the density of a hair follicle? Multiple hair follicles already have density. To multiply, you only need to copy the original density. If a hair follicle doesn't have density, how can you copy the density?" Ivan didn't understand the trick.
"It's very simple. There are only hair follicles. There is no reference for the reproduction of density. It is random. We let it multiply. The hairs in the multiplied skin patches may be sparse or dense. We can cut off the skin patches according to the density requirements. Hold this The skin slices are used as skin sources to be cultivated again," Tang Shun explained clearly.
"Ingenious!"
Ivan had to admire their ideas for solving problems, which were very sparkling.
"What is here?"
Ivan noticed that the shape of the medium used for skin graft attachment during this culture period was not flat, but spherical. If you look carefully, it is the shape of the head. If you look more carefully, the attachment medium is shaped like a head. This is Teacher Sun’s head model.
"Why is this?" Ivan pointed to the medium of the head model.
Tang Shun knew that this new technology was a mystery to Ivan, so he had to explain: "Aren't you going to have a scalp transplant in your next surgery? With such an attachment medium, the skin graft will crawl and grow along the model, and finally It forms a hood-like shape. During the operation, you only need to put the hood over your head, make holes evenly, pull the mesh slightly, and then use VSD negative pressure suction. Isn’t it a perfect scalp transplant? ”
"Great! And it looks very comfortable." Ivan gave a thumbs up after hearing the explanation.
The harvest from this trip to China is really great, much greater than expected.
"So? This prefabricated skin grafting method can be used for skin grafting on complex-shaped parts such as hands and feet?" Ivan was very excited.
In the past, he often used 3D printing technology to assist in plastic surgery, such as rhinoplasty surgery. He used 3D printing technology to print out the cartilage he wanted, and then implanted it into the patient's body to achieve the desired effect.
However, skin grafting cannot do this. For some three-dimensional parts, splicing can only be used to shape the three-dimensional shape of the package.
As for the face being shaped in one go, that’s because the face is generally relatively flat.
If it's the head, it's spherical and cannot be formed in one go.
This principle is like not using cutting and splicing technology. You can cut out a facial mask from a piece of paper, but you cannot cut out a pair of gloves.
This skin flap shaping technology is the real three-dimensional shaping technology.
We are discussing technology here.
On the other side, Song Zimo, Xu Zhiliang, August and Robert surrounded Fatty Liang to learn about his recent learning experience from Tang Shun.
(End of chapter)