Chapter 162 The simulation laboratory automatically hangs up!
In the next few days, with Zhang Yang’s help, the first project team’s research and development on the “sAC cyclase activity generator” made rapid progress.
More than a dozen "lead compounds" that are effective at the target have been "accidentally" discovered and then quickly assigned to scientific researchers for the next step of re-screening.
Of course,
Although Zhang Yang knows which of the most effective "compounds" is, he cannot directly tell the R&D personnel the correct answer among more than a dozen "lead compounds" .
But in the following days, he would come to the first project team every few days to understand the progress of the research and development, and by the way put forward some "valuable opinions" to quickly help the research and development team narrow down the scope.
It is no exaggeration to say that his opinions reduced the development time of the first project team by at least 1-2 years!
While helping the first project team to develop the "sAC cyclase activity generator", Zhang Yang was not idle.
After learning that the "Simulation Laboratory" development time rate was as high as 1:10, he excitedly prepared to start another infertility drug in the "Simulation Laboratory", which was to treat "abnormal sperm" disease” drug development.
Because this drug involves a variety of male hormones and covers multiple organs such as the pituitary gland and testicles, its pathological mechanism is complex and its research and development is very difficult.
Therefore, even the Qingshan Pharmaceutical R&D Center had no project team willing to take over.
Now that it's fine, he simply put it in the "simulation laboratory" for research and development, starting from scratch, starting from finding drug targets.
One day, two days, three days.
Zhang Yang is immersed in the simulator every night, intensely searching for drug targets for "teratozoospermia".
But on the fourth day, he began to feel that the intensity was too great, especially after eight hours of high-intensity simulation one night. His brain did not get a rest, and he was very depressed the next day.
He has realized that if he were just a simple drug developer, the 1:10 time speed in the simulation laboratory would undoubtedly make him even more powerful, and the various new drug projects at hand would be successfully developed at an unexpected speed.
But.
After all, I am the boss of Qingshan Pharmaceutical. I have to deal with the affairs of Qingshan Pharmaceutical during the day, and I always have to rest at night.
“It seems that this function is still a bit useless. It would be great if I could hang up the research and development.”
“Set the research and development direction and experimental content yourself, and then the simulation laboratory will follow your own ideas and Conduct data experiments in the direction and finally obtain experimental data.”
"For example, in reality, I only need to arrange it, and the R&D team will give me the final test results according to its own ideas!"
"Unfortunately, this simulator is still slightly inferior, and I still have to do it myself. ”
The sigh echoed in the simulation laboratory, but the words just The system sound suddenly sounded:
"Dear host, this simulation laboratory has activated the automatic hosting R&D function."
"You only need to set the R&D direction and Test content, the simulation laboratory will simulate according to your ideas. ”
Zhang Yang was stunned, and then he was pleasantly surprised!
Is this really possible? !
In this case, doesn’t it mean that you only need to provide the research and development direction, and the process can be left to the simulation laboratory to slowly simulate it?
This is so easy!
Careful! How thoughtful!
However, he soon realized that if he wanted to simulate the research and development of automatic AFK in the laboratory, he would probably need to pay energy points.
"Do you need energy value?"
"Yes, the host. The simulation laboratory can host research and development for up to 10 hours a day, and you need to pay 1 energy value per hour."
< br>"The simulation efficiency is equivalent to that of your own test."
Sure enough.
Zhang Yang couldn't help but shake his head, there really is no such thing as a free lunch.
This is equivalent to spending 10 energy points to hire a "self" to conduct a ten-hour experiment...
However, even if the joy in my heart is diluted a little, it must not be I can’t help but lament that the “Simulation Laboratory” function is too comprehensive.
Compared with the previous one-time payment of 50 points or 100 points, the "lottery-style" breakthrough simulation is completely led by the system. Although this method takes longer,
But as long as your research and development direction is correct, the energy value should be much less.
Of course, the premise is that the research and development direction must be correct.
Thinking of this, Zhang Yang immediately paid 10 energy points, and then set his direction for finding the target of the "teratozoospermia" drug.
Soon a prompt sound came from the system.
"Congratulations to the host for successful payment. The simulation laboratory will immediately carry out simulations according to the research and development direction required by the host."
"This consumption consumes 10 energy points. Please check this time after ten hours. Simulation test results.”
"You still have 190 energy points left."
"Another 10 points have been consumed..."
Looking at 10 energy points consumed again, Zhang Yang is painful and happy, the energy value So useful!
He immediately thought of the system prompt yesterday and wanted to obtain energy values:
The first is to complete the "plot simulation";
The second is to complete the research and development tasks released by the "Simulation Laboratory";
The third is to provide the "Simulation Laboratory" with complete drug data patented by the host.
Currently, there are no new plots and tasks in the first and second methods. The only way to obtain energy points is in the third method.
For example, "ITG human myelopoietin" itself is provided by the simulator, and it is naturally impossible to share it with the simulator.
Independently developed by Qingshan Pharmaceutical...
There are only "Macromolecular Toxin Catalyst" that was bought out from BI Company and "sAC Male Contraceptive Pill" that was just independently developed.
According to the requirements of the simulator, Zhang Yang quickly uploaded the compound patents, crystal form patents, animal experiment data and other information of the two drugs.
About five seconds later, a crisp prompt sounded:
"'Macromolecule Toxin Catalyst' was shared successfully and has been entered into the 'Simulation Laboratory Drug Database'!"
"This drug is determined to be a Class C auxiliary treatment drug. It is mainly used as an auxiliary drug for renal dialysis. The reward energy value is 400 points. (Initial value 300 points + floating value 100 points.)"
"'sAC male contraceptive pill' has been shared successfully and has been entered into the 'simulation laboratory database'!"
"This drug is determined to be a C-level auxiliary drug, mainly used for male contraception, and rewards 300 energy points."< br>
"You currently have 890 energy points left."
Both drugs are actually only C-level drugs...
And!
The energy value of this reward is too small. The total of the two drugs is only 700 points. You must know that the previous breakthrough in the development of "sAC cyclase activator" in the simulator cost 800 points for 50% of the semi-finished product!
“That’s all, this energy value reward should be that the rarer the drug, the better the effect, and the higher the level, the more valuable it is!”
“Waiting for Qingshan Pharmaceutical R&D Center to develop drugs such as cancer later. After taking targeted drugs, the energy value of the reward should be more!" After discovering the automatic hang-up function of the simulation laboratory, Zhang Yang's efficiency increased significantly instantly.
Every morning he paid 10 energy points on time to start the simulation, and then waited until the next morning to check the previous day's research and development results.
During the R&D process, while checking the test results, he was also adjusting his R&D ideas based on the test data, just like real-life R&D.
Of course, he can also use the simulation laboratory to pay 50 energy points at a time for "quick target exploration",
But Zhang Yang has already asked the system, the more complex the disease, For example, diseases such as "teratozoospermia" and "azoospermia" whose pathological mechanisms are not yet clear, require more and more simulation data.
The target is often found not once, twice, or ten times.
Unless it is the European Emperor.
There was no rush for the "teratozoospermia" project, and Zhang Yang didn't want to give it a try, so he simply conducted drug research and development in the traditional way.
Unknowingly, ten days passed quietly, and Zhang Yang had paid 100 energy points for this.
Ten days means 100 hours, which is already 1,000 hours when converted into real time.
Based on an 8-hour working day, Zhang Yang has spent 125 working days, or 4 months, on research and development, and the research and development data he obtained is indeed roughly the same as the actual progress of 4 months.
Although the exact target of the "teratozoospermia" disease has not yet been discovered, there are already some clear ideas.
While Zhang Yang was exploring targets for "teratozoospermia", he also continued to follow up on the development of "sAC cyclase" for the treatment of asthenozoospermia at the Qingshan Pharmaceutical Drug Research and Development Center.
The progress of "sAC cyclase activator" has been reduced and only a few "lead compounds" need to be screened. The next step is to "optimize the molecular structure of the compound" and then start animal experiments.
While Zhang Yang was busy at both ends, Liu Qiang and Xu Min also experienced an unforgettable month.
To be precise, the two of them couldn't wait to call Dr. Feng Yan's expert number again on the 28th day before a month had passed.
When they arrived at the Reproductive Technology Department of the Third People's Hospital of Chengdu again, their moods were completely different from a month ago.
In the past month, they have learned more about infertility from the Internet, and the more they read, the more worried they become!
Especially when they saw on the Internet a patient with almost the same "asthenozoospermia" + "severely abnormal sperm" as Liu Qiang, who could not even get pregnant successfully through in vitro fertilization, they were completely panicked.
What should I do if I can’t get pregnant even with IVF?
Don’t want children for the rest of your life?
Standing at the door of the Reproductive Technology Department, Xu Min looked at the nervous Liu Qiang and comforted:
"Husband, don't worry too much. We have been recovering for a month, and things should get better."
"Yes."
Liu Qiang breathed a sigh of relief, and after a while, the two of them Meet Dr. Feng Yan.
The same process as last time, first take the sperm for testing, and the results will come out an hour later.
In the outpatient clinic, doctor Feng Yan looked at the examination results in front of her and called up the comparison results from a month ago on the computer, frowning slightly.
"Liu Qiang, the results of your examination last month: only 2 of the 286 sperm were of normal shape, and the remaining 284 were all deformed; moreover, the rate of all sperm moving forward in a straight line was 0."
" This time, not only the sperm's ability to move straight forward It is still less than 1%, and the rate of abnormal sperm has not improved. There are only two normal sperms out of three hundred sperm."
"This situation..."
Feng said. Yan's eyes first glanced at Xu Min, and finally fell on Liu Qiang.
“If you want to have a child in this situation, you can only consider in vitro fertilization.”
Test tube baby!
When these four words came out of the doctor's mouth, even though they were somewhat prepared, Liu Qiang and even Xu Min couldn't help but tremble, and an indescribable sadness surged through them. Come to mind.
Especially Liu Qiang,
He lowered his head slightly, his eyes dropped to his chin, his face full of sadness.
In the past month, he has been exercising every day, running and sitting for a while every day, and going to bed at 9 o'clock in the evening. He is looking forward to getting better after this examination and giving him some hope.
Unexpectedly, there was no improvement at all!
After being silent for thirty seconds, Liu Qiang sighed heavily:
"Doctor, I understand, I also saw on the Internet that my problem is more serious."
"However, I still can't accept direct in vitro fertilization. Many people on the Internet say that we can try 'artificial insemination' first. I think..."
"You want to try artificial insemination first?" ”
Liu Qiang nodded.
First of all, he still hopes to have a normal pregnancy.
Secondly, he has learned about the cost of artificial insemination, which is about 7,000 yuan per time, while in vitro fertilization is much more expensive.
However, doctor Feng Yan shook her head and refused:
“You should have understood what artificial insemination is, right?”
"It means that the male semen is screened out with qualified sperm through professional instruments, and the viable sperm are concentrated;
Then these viable sperm are transported into the female uterine cavity through the 'insemination catheter' , allowing it to combine with the egg.”
< br>"Generally speaking, if the sperm activity is low and the deformity rate is not too high, we will consider allowing the patient to undergo 'artificial insemination'."
"But in your case..."
< br>Feng Yan paused and breathed out gently:
"Let me tell the truth, artificial insemination is not suitable for you. Although you have sperm of normal shape, the activity is too low and the number is too small!"
"In this case, you can only do second-generation IVF, or even , the second generation test tube baby may not be able to conceive!”
Doctor Feng Yan’s words completely shattered the last trace of their illusions.
Xu Min, who had been silent for a long time, looked anxious, obviously unable to suppress panic:
"Doctor, we want children, and we are willing to do in vitro fertilization."
< br>
"If we do in vitro fertilization, what is the success rate in a situation like ours?"
Feng Yan's expression also softened and she explained:
"IVF has now reached the third stage. Generation.”
“The first generation of in vitro fertilization can be understood as combining male sperm and female sperm. The normal fertilization of eggs means that they are naturally fertilized in an in vitro culture dish. "
"The second-generation test-tube baby has severe asthenozoospermia like yours, accompanied by severe teratozoospermia. , our medical staff precisely injects the sperm into the egg’s cytoplasm.”
"The third generation of test-tube babies is mainly used for couples with genetic diseases, such as albinism, etc... You don't consider this!"
"However, you must be mentally prepared. Even if your situation is the first The success rate of second-generation test tubes is not high, and The cost is relatively high!”
Xu Min hesitated for a moment and looked at Feng Yan sadly:
“Doctor, how much is it?”< br>
(End of this chapter)