Chapter 250: Promote Mien, fight against Mien.
Rongcheng Third People's Hospital, Department of Hematology.
Director Hu had just finished the rounds in the ordinary ward and returned to the office. After two minutes, a crisp knock on the door sounded.
"Please come in."
After the words, a middle-aged woman dressed in jewels walked in.
Director Hu looked up and frowned, with some eyes.
"Hello, Director..."
The middle-aged woman with jewels showed a hint of embarrassing but flattering smile on her face, and at the same time, she closed the office door with her backhand so that only a thin slit is left: br>
"Director, I am Huang Xiaoyun's family in bed 21. My son participated in the second phase clinical trial of Qingshan Pharmaceutical's 'Yibaichunbacter'. Uh... it's the double-blind test."
"By the way, do you still remember me? We were introduced by Director Duan of the Endocrinology Department before. My wife is Director Duan's classmate. Director Duan also called you personally..."
"Oh?"
Director Hu looked at the middle-aged woman in front of him again and had some impression in his mind.
In fact, as the director of a department in the top ten hematology departments in the country, it is inevitable that they will receive some patients who say hello.
If you have the hope of giving priority to medical treatment, you also have the hope of arranging a bed.
Generally speaking, as long as the regulations are not violated, he will try his best to satisfy himself, which is also human nature.
The family of the middle-aged woman in front of her seemed to have indeed been introduced by Director Duan to join the clinical trial of "Yibaizumab"...
Thinking of this, a smile appeared on his face and said: br>
"Oh, I remember!"
"Sit down first, what's wrong? Did you encounter something?"
"Isn't it happened to me? Now! ”
The middle-aged woman saw Director Hu remembering this relationship and her smile on her face became more attentive: "Director, I heard many people say yesterday that what combination treatment plan is the latest launched by Qingshan Pharmaceutical is very good ;
It is said that those subjects have achieved the lowest treatment effect after use, and the best ones cannot even detect leukemia cells! It is even more effective than magical medicine! "
"So Director, can you please help us, so that our Xiaoyun can also use this latest combination treatment plan as soon as possible?"
Director Hu instantly understood the purpose of the middle-aged woman in front of him.
Patients participating in the first and second phase double-blind tests of clinical trials were also treated alone with the initial "Ibaimab". At this time, patients who heard that the combined treatment effect of independent medication was significant, who was not moved?
Who is not jealous?
But...
After a moment, he shook his head and said, "This family member, this matter is not something I can decide; clinical phase one and two phases Qingshan Pharmaceutical is fully responsible for what treatment plan to use for double-blind test patients, and I am powerless."
"Besides, you also know that this experiment was conducted with a double-blind test. Even if Qingshan Pharmaceutical really uses a combination treatment plan in the first and second phase clinical phases, your son may not be able to use it as soon as possible."
"So, don't worry, take your time!"
Director Hu originally thought that such a remark was enough to dispel the middle-aged woman's idea, but he didn't expect that the middle-aged woman suddenly blinked her eyes and said mysteriously. :
"Director, I can be sure that my son must be in the 'test group'!"
"To be honest, I have secretly read my son's inspection report in the past month. Many core indicators are better than before we participated in clinical trials, and this is definitely the effect of 'Yibaizumab'! ”
"So..."
As he said, the middle-aged woman paused slightly, and a diligent smile appeared on her face again:
"So, can you please help me, you gave Qingshan Medicine The industry reported that they should hurry up and perform joint treatment in the double-blind experimental group. "
After listening, Director Hu's expression was still normal.
Generally speaking, double-blind tests follow the "double-blind rules" of patients, the person in charge of developing clinical trial plans, and the reviewers who are the trial group and who are the placebo group.
But there are always some patients with great powers who can judge whether they belong to the experimental group through various methods.
At this moment, he also turned on the examination results of Huang Xiaoyun, a patient on the computer. As expected, he said similar to what the middle-aged woman said. The recent treatment effect is quite good, and it is indeed very likely that she was assigned. Test group.
After thinking for a while, Director Hu did not intend to continue talking about this topic, and said in a deep voice: "Okay, I won't discuss the issues of the experimental group for now."
< br>"I understand your feelings, but what you don't understand is that this combination treatment plan actually has a great risk of side effects. Those severely ill patients who use combination treatment have signed a disclaimer agreement."
"Side effects?"
The middle-aged woman finally looked stunned, but soon she shook her head and said: "Director, I think they have used it for a week, but there are no side effects. Ah! ”
Director Hu was a little amused and crying. This woman was really a little difficult to deal with.
But when I think of it as a friend introduced by Director Duan, I could only explain patiently:
"You said it only took one week. What side effects can a week of this? You still need to continue to observe."
"You still need to observe?"
The middle-aged woman was suddenly excited. Get up: "Director Hu, then when will we use it? We are not afraid of side effects, so please help me report it to Qingshan Pharmaceutical." Director Hu sighed helplessly After breathing a sigh of relief, he didn't want to explain anymore, so he had to say perfunctorily:
"Okay, I'll give Qingshan Pharmaceutical some advice."
...
Mid-aged woman was the first to come to see Director Hu, but not the last one.
In the next two or three days, many patients who participated in the first and second phase double-blind tests of clinical trials have found Director Hu, hoping that he can help him report it to Qingshan Pharmaceutical so that everyone can use it as soon as possible Combination treatment options.
Director Hu explained patiently at first, but in the end he was asked too much, he was a little impatient. He originally thought that this matter would slowly silence, but he didn't expect that in a few days, some unfriendly things would be a little unfriendly. The sound gradually came from the patient's family.
In the ward of the hematologic department. "Hey, I don't know if Director Hu didn't report this to Qingshan Pharmaceutical, or if Qingshan Pharmaceutical doesn't care about our thoughts at all. It's been so many days since Qingshan Pharmaceutical still hasn't taken action!"
"Hmph, it must be Qingshan Pharmaceutical. Director Hu said everything. He couldn't make the decision on this matter, and it was up to Qingshan Pharmaceutical to decide."
"Well, right? , I also think Qingshan Pharmaceutical doesn't want to adjust it, it's said...ah, I also heard that Qingshan Pharmaceutical attaches great importance to this 'Yibaichunbacter' and is preparing to make a big profit on this drug. As for one transaction, so... now I can't bear to give us a combination of medicines, so I just waited for the drug to be launched before we bought it. They made a lot of money! "
"Ah? No way? Qingshan Pharmaceutical The industry has never been like this! ”
"That's right, I may still believe other companies, but Qingshan Pharmaceutical lacks the money we have? Besides, whoever pharmaceutical company wants to do clinical trials to have good treatment results. The better the effect, the easier it is to pass."
"Hmph, if you don't believe it, then why do you think the combination treatment plan is so effective now? Qingshan Pharmaceutical just doesn't use it for us? Don't talk about any side effects, why didn't I see those patients appear? Side effects? They are all lively and look better than us! " "Also, the drug you mentioned has been successfully launched. Aren't those patients who use independent drugs the best data? Are they afraid that they can't go to the market?"
"So, Qingshan Pharmaceutical just doesn't care about us at all, and is even afraid that our condition will be well controlled and will affect their sales at that time!"
"It's simply nonsense. ! ”
It has to be said that these rumors are simply not logical, and anyone with a little bit of common sense in medical research and development knows that this is nonsense.
But most patients and their families are ordinary people, and they have no knowledge about drug development.
In addition, in everyone's eyes, Qingshan Pharmaceutical does not provide the "best" treatment plan, and this conspiracy theory has a market share among the patient population!
For a time, a large number of rumors and slander spread among the patient's family!
Director Hu was so angry that his teeth were itchy, but Zhang Yang was busy with another thing.
Just the day after the effect of the combination of "Ibaimab" was announced, Friedman, who had not seen for a long time, appeared in his office.
"Zhang, long time no see! I saw the latest news about your 'Yibaizumab' from the news, crazy!"
"You are going to make a big profit again!"
"You are going to make a fortune again!" "Haha, Friedman, I'll lend you auspicious words!"
No mistakes, one song, one content, one book, one book, one bar, one reading!
Zhang Yang was not surprised by Friedman's arrival, and he had even been waiting for a long time.
You should know that GlaxoSmithKline's Lucas signed a cooperation letter for "Ibaimumab" with Qingshan Pharmaceutical two weeks ago. Novartis' reaction this time was so slow, but it was a bit abnormal. .
However, what surprised Zhang Yang even more was that Friedman brought a new face this time.
A beautiful woman who looks very delicate and conforms to the oriental aesthetic.
"Zhang, let me introduce you to Miss Minako and the latest vice president of our Novartis China headquarters. Next, we will be responsible for the cooperation and contact with your company."
"Or to be precise, Miss Minako will serve you specifically."
Specially serve me?
Zhang Yang was slightly stunned, but before he could think about it, Minako, who was beside him, suddenly showed a sweet smile, stretched out his right hand generously, and said: "Mr. President, my name is Minako, I'm very happy to know you."
"I'm a mixed Chinese and Japanese race. I also have a Chinese name. You can also call me Lin Yue."
"Just as President Friedman said, I will stay at the headquarters in China for a long time, mainly responsible for all cooperation with your company, and I will also ask you for advice."
Zhang Yang then slowed down It’s no wonder that Minako in front of her looks so pleasing to the eye. She turns out to be a mixed-race of Chinese and Japanese.
He subconsciously looked at Minako's eyes again, then stretched out his right hand and gently held it, as soft as boneless, delicate and smooth, which made his heart slightly sway.
Zhang Yang couldn't guess at the moment Friedman specifically introduced Minako to himself, but he was too lazy to think too much at this time. He knew that the most important purpose of Friedman's trip must be with Qingshan Pharmaceutical. The industry signed a letter of intent for agency cooperation of "Yibaichunbacter".
Sure enough, Feridman then mentioned the agency of "Iberumab" in the United States.
Zhang Yang didn't talk much. At this moment, his focus was on monitoring the side effects of the combined treatment of "Yibaizumab", and he didn't want to waste more time on this matter.
In addition, I have worked with Novartis many times before, and soon both parties have reached a preliminary intention cooperation agreement.
Friedman seemed to notice that Zhang Yang was not very interested. After signing the contract, he chatted for a few words and prepared to leave.
Before saying goodbye, Minako took the initiative to hand Zhang Yang a card.
"President Zhang Yang, this is my business card."
"I have my private phone number on my business card, and I welcome you to call me at any time."
"If you need it, I can fly over from the demon city at any time."
Zhang Yang took it The business card handed over by Minako with both hands suddenly understood after a simple glance.
He smiled indifferently:
"Okay, I will call you if there is any cooperation."
…
Friedman and Minako come and go quickly, and just when Friedman came to Qingshan Pharmaceutical to sign the "Ibaimab" intention cooperation agreement, another world-class company Pharmaceutical company Pfizer also noticed the amazing effect of Qingshan Pharmaceutical's combined treatment of "Yibaizumab".
Pfizer, USA.
Pfizer was originally developing a drug about acute leukemia.
Pfizer was so acidic when Qingshan Pharmaceutical's "Yibaimab" first started to conduct clinical trials. At this time, he saw Qingshan Pharmaceutical use of "aliomeric T cells" + "Yibaimab" combined with "Yibaimab". After the treatment achieved even more amazing treatment results, all the sour teeth fell off.
However...
Pfizer is also worthy of being the world's top pharmaceutical company.
As a new immune drug for tumor treatment, Pfizer's senior technicians quickly noticed the possible problems in Qingshan Pharmaceutical's combined treatment plan!
That's right!
That is the side effects brought by "alloy T cells"!
President Daniel's office.
"Mike, are you saying that the combination treatment plan in Qingshan Pharmaceutical's clinical trial is very risky? Is it very likely to cause the patient's organ failure?!"
"No Wrong, President Daniel. "
The answer was Mike, the director of the technical research and development department. After seeing the clinical trial plan and results released by Qingshan Pharmaceutical, he was also shocked at the first time.
Shocked Qingshan Pharmaceutical to achieve such stable and efficient therapeutic effects.
But soon, he discovered "alloy T cells" and discovered possible side effects in this combination therapy regimen.
"President Daniel, our team has a lot of knowledge about 'allotype T cells', and I can confirm that the use of 'allotype T cells' drugs will bring many side effects."
"Especially for use In patients with leukemia, this side effect may be exponentially amplified, and long-term use is very likely to cause abnormal or even failure of the originally normal bone marrow hematopoietic stem cells! "
"I don't know if Qingshan Pharmaceutical is aware of this point No, but I think this must be a huge hidden danger..."
"It's so huge that if they don't have a good solution, the launch of this 'Yibaizumab' may be affected!"
"Will the ethics committee member let such serious side effects be launched on the market!"
President Daniel was slightly stunned, and then a strange light flashed in his eyes.
Qingshan Pharmaceutical has been in the limelight in recent years!
Especially, some time ago, he "snatched" the Saudi royal "order" of hemophilia from Pfizer! "Haha, no matter whether they know the possible side effects, it will cause them some trouble."
PS: Thank you for your monthly tickets. Today I went home after traveling to the home, and I will start to make an update tomorrow!
Thank you for your support!
(This chapter ends)